Systems, methods, and devices for assessing microbiota of skin
First Claim
1. A device comprising:
- a skin-covering substrate sized to cover at least a portion of an individual'"'"'s face, the skin covering substrate including an inner surface and an outer surface, the inner surface of the skin covering substrate substantially conforming in shape to a topography of a skin surface of the at least a portion of the individual'"'"'s face, the inner surface of the skin covering substrate including attached thereto a plurality of signal-generating complexes, each of the plurality of signal-generating complexes including at least one signal-generating element operably coupled to at least one specific microbe-binding element, wherein each of the plurality of signal-generating complexes is configured to emit one or more signals from the at least one signal-generating element in response to a specific microbe type interacting with the operably coupled at least one specific microbe-binding element.
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Accused Products
Abstract
Devices, systems, and methods for assessing microbiota of skin are described, including: a skin-covering material including an inner surface and an outer surface, the inner surface substantially conforming to a topography of a skin surface of an individual and including a plurality of signal-generating complexes, one or more of the plurality of signal-generating complexes configured to emit one or more signals in response to at least one type of microbe; an image capture device to capture an image of the inner surface of the skin-covering material, the image including one or more signals emitted from the plurality of signal-generating complexes, and to transform the image into a digital output; and a computing device including circuitry configured to receive the digital output, compare the properties of the imaged one or more signals with a database of reference signal-generating complexes, and generate a digital spatial profile of microbes on the skin-covering material.
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Citations
43 Claims
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1. A device comprising:
a skin-covering substrate sized to cover at least a portion of an individual'"'"'s face, the skin covering substrate including an inner surface and an outer surface, the inner surface of the skin covering substrate substantially conforming in shape to a topography of a skin surface of the at least a portion of the individual'"'"'s face, the inner surface of the skin covering substrate including attached thereto a plurality of signal-generating complexes, each of the plurality of signal-generating complexes including at least one signal-generating element operably coupled to at least one specific microbe-binding element, wherein each of the plurality of signal-generating complexes is configured to emit one or more signals from the at least one signal-generating element in response to a specific microbe type interacting with the operably coupled at least one specific microbe-binding element. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A system comprising:
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a skin-covering substrate sized to cover at least a portion of an individual'"'"'s face, the skin-covering substrate including an inner surface and an outer surface, the inner surface of the skin-covering substrate substantially conforming in shape to a topography of a skin surface of the at least a portion of the individual'"'"'s face, the inner surface of the skin-covering substrate including attached thereto a plurality of signal-generating complexes, each of the plurality of signal-generating complexes including at least one signal-generating element operably coupled to at least one specific microbe-binding element configured to specifically recognize and bind at least one specific microbe type, wherein each of the plurality of signal-generating complexes is configured to emit one or more signals from the at least one signal-generating element in response to the at least one specific microbe type interacting with the operably coupled at least one specific microbe-binding element; and an enhancing component configured to enhance binding of the at least one specific microbe type from the skin surface of the individual to the at least one specific microbe-binding element of the signal-generating complex attached to skin-covering substrate. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37)
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38. A system comprising:
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an electromagnetic energy source; a settable liquid or gel configured for application to a skin surface of an individual, the settable liquid or gel configured to undergo a phase change to a solid form in response to an applied stimulus from the electromagnetic energy source; and a plurality of signal-generating complexes, each of the plurality of signal-generating complexes including at least one signal-generating element operably coupled to at least one specific microbe-binding element, the at least one signal-generating element of the signal-generating complex configured to emit a signal in response to at least one specific microbe type interacting with the operably coupled at least one specific microbe-binding element; wherein the plurality of signal-generating complexes are dispersed in the settable liquid or gel. - View Dependent Claims (39, 40, 41, 42, 43)
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Specification