Diagnostic measuring device

• US 10,226,190 B2
• Filed: 03/05/2010
• Issued: 03/12/2019
• Est. Priority Date: 03/05/2009
• Status: Active Grant

• Current Assignee: Ingo Flore
• Original Assignee: Ingo Flore
• Inventors: Kim, Yoon Ok, Cho, Ok Kyung
• Primary Examiner(s): Pehlke, Carolyn
• Application Number:
  US13/138,555
• Publication Number:
  US 20120016210A1
• Time in Patent Office: 3,294 Days
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/0008 Temperature signals
• CPC Class Codes: A61B 5/0017 transmitting optical signals transmission by light H04B10/00
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6838 Clamps or clips
• CPC Class Codes: A61B 5/6843 Monitoring or controlling sensor contact pressure

Abstract

The invention relates to a diagnostic measuring device for non-invasively collecting at least one physiological parameter of body tissue by way of an optical measuring unit (100), comprising at least one source of radiation (4) for irradiating the body tissue to be examined, and at least one radiation sensor (5) for detecting the radiation scattered and/or transmitted by the body tissue. The invention proposes the arrangement of the at least one source of radiation (4, 702) within a hollow reflector (701).

Claims

1. A diagnostic measuring device for non-invasive determination of at least one physiological parameter, the diagnostic measuring device having an optical measuring unit that comprises:

at least one radiation source for irradiating a body part of a patient,

at least two radiation sensors configured to detect radiation scattered and/or transmitted by the body part and configured to measure optical measurement values in the form of light intensities comprising transmitted intensity I_T and/or intensities I_Rs1 and I_Rs2 that are scattered back from different tissue regions,

at least one hollow reflector, the at least one radiation source being disposed in the at least one hollow reflector, and

a first radiation exit and a second radiation exit connected to the at least one hollow reflector, and

an optic configured to collect and emit radiation,

wherein the at least one radiation source emits radiation in the hollow reflector so that a diffusion level of the radiation in the hollow reflector is increased, so that diffused radiation is produced, and so that the diffused radiation is then conducted via the first radiation exit and via the second radiation exit,

wherein the first radiation exit comprises or is connected to the optic such that the optic is configured to collect the diffused radiation and to emit the diffused radiation as a first radiation beam at a first opening angle,

wherein the second radiation exit is configured to emit the diffused radiation as a second radiation beam differently shaped from the first radiation beam and at a second opening angle,

wherein the first radiation beam and the second radiation beam have different spatial characteristics and are configured to irradiate different volume ranges of the body part, and

wherein the first opening angle is different from the second opening angle.

2. The diagnostic measuring device according to claim 1, further comprising a temperature or heat sensor.

3. The diagnostic measuring device according to claim 2, wherein the at least one radiation source, and the at least one hollow reflector, the first radiation exit, the second radiation exit, and a first element are disposed in a common sensor housing, and

wherein the first element is selected from the group consisting of at least one electrode for EKG measurements, at least one electrode for bioelectrical impedance measurements, and the temperature or heat sensor.

4. The diagnostic measuring device according to claim 1, further comprising at least one electrode configured as a flat foil or sheet.

5. The diagnostic measuring device according to claim 1, further comprising

at least one electrode having at least one recess, and

a temperature or heat sensor,

wherein at least one first element is disposed in said at least one recess, said at least one first element being selected from the group consisting of:

an end of the first radiation exit,

the at least one radiation sensor, and

the temperature or heat sensor.

6. The diagnostic measuring device according to claim 1, further comprising at least one electrode configured to perform an EKG measurement and configured to perform a bioelectrical impedance measurement.

7. The diagnostic measuring device according to claim 1, further comprising a first electrode for bioelectrical impedance measurements and a second electrode for bioelectrical impedance measurements,

wherein a distance between the first electrode and the second electrode is less than 10 cm.

8. The diagnostic measuring device according to claim 1, further comprising at least one feeder electrode for bioelectrical impedance measurements,

wherein the at least one feeder electrode applies alternating current of variable frequency.

9. The diagnostic measuring device according to claim 8, further comprising at least one measuring electrode for bioelectrical impedance measurements,

wherein the at least one feeder electrode and the at least one measuring electrode are configured as contact strips that run parallel to each other.

10. The diagnostic measuring device according to claim 1, further comprising

at least two measuring electrodes for bioelectrical impedance measurements, and

a computer programmed to determine changes of a local impedance measurement signal over time.

11. The diagnostic measuring device according to claim 1, further comprising a sensor housing, measuring and/or feed electrodes, and a fixation device configured to fix the body part of the patient to be examined in place on the sensor housing, the fixation device being selected from the group consisting of:

a finger clamp, and

an inflatable air cushion configured to press the body part against the measuring and/or feed electrodes.

12. The diagnostic measuring device according to claim 1, wherein the at least two radiation sensors are disposed at different distances from the at least one radiation source.

13. The diagnostic measuring device according to claim 1, wherein the hollow reflector comprises a chip housing that accommodates the at least one radiation source and the at least two radiation sensors within itself,

wherein the at least one radiation source and the at least two radiation sensors, in each instance, comprise at least one semiconductor body that:

is connected to conductor tracks that run in the interior of the chip housing and/or

comprises bond wire connections, and

wherein the chip housing has the first radiation exit and the second radiation exit on its top.

14. The diagnostic measuring device according to claim 13, wherein the at least one hollow reflector further comprises a transparent plastic material that fills the chip housing.

15. The diagnostic measuring device according to claim 13, wherein the chip housing has a passage opening on its top configured to receive the radiation scattered and/or transmitted by the body part.

16. The diagnostic measuring device according to claim 1, wherein the optic is configured to produce the first radiation beam as a directed emission.

17. The diagnostic measuring device according to claim 1, further comprising electrodes for EKG measurements.

18. The diagnostic measuring device according to claim 1, further comprising electrodes for bioelectric impedance measurements.

19. The diagnostic measuring device according to claim 1, further comprising

a housing comprising the at least one radiation source, the at least one hollow reflector, the first radiation exit, and the second radiation exit, and

at least one electrode disposed at or on a surface of said housing,

wherein the optical measuring unit is configured to emit the first radiation beam and the second radiation beam to the body part in a first body region or to detect the radiation scattered and/or transmitted from the body part in a first body region, and

wherein said at least one electrode is configured to touch a skin surface in the first body region.

20. The diagnostic measuring device according to claim 1, wherein the at least one hollow reflector comprises an Ulbricht sphere.

21. The diagnostic measuring device according to claim 1, further comprising a computer programmed to determine at least one physiological parameter selected from the group consisting of:

an arterial oxygen saturation,

a venous oxygen saturation,

a capillary oxygen saturation,

a local oxygen consumption,

a local glucose concentration,

a glucose level,

a heart rate,

a fat content of the body tissue, and

a water content of the body tissue.

22. A system comprising:

a diagnostic measuring device for non-invasive determination of at least one physiological parameter, and

a portable device or a portable accessory, the portable device or the portable accessory being connected to the diagnostic measuring device,

wherein the diagnostic measuring device has an optical measuring unit comprising;

at least one radiation source for irradiating a body part of a patient,

at least two radiation sensors configured to detect radiation scattered and/or transmitted by the body part and configured to measure optical measurement values in the form of light intensities comprising transmitted intensity I_T and/or intensities I_Rs1 and I_Rs2 that are scattered back from different tissue regions,

at least one hollow reflector, the at least one radiation source being disposed in the at least one hollow reflector,

a first radiation exit and a second radiation exit connected to the at least one hollow reflector, and

an optic configured to collect and emit radiation,

wherein the at least one radiation source emits radiation in the hollow reflector so that a diffusion level of the radiation in the hollow reflector is increased, so that diffused radiation is produced, and so that the diffused radiation is then conducted via the first radiation exit and via the second radiation exit,

wherein the first radiation exit comprises or is connected to the optic such that the optic is configured to collect the diffused radiation and to emit the diffused radiation as a first radiation beam at a first opening angle,

wherein the second radiation exit is configured to emit the diffused radiation as a second radiation beam differently shaped from the first radiation beam and at a second opening angle,

wherein the first radiation beam and the second radiation beam have different spatial characteristics and are configured to irradiate different volume ranges of the body part, and

wherein the first opening angle is different from the second opening angle.

23. The system according to claim 22, wherein the portable device or the portable accessory is an entertainment device having communications technology and is a notebook, a laptop, a mobile telephone, a palmtop, or a handheld.