System, method and computer program product for physiological monitoring

• US 10,226,217 B2
• Filed: 10/24/2016
• Issued: 03/12/2019
• Est. Priority Date: 10/22/2015
• Status: Active Grant

• Current Assignee: Tyto Care, Ltd.
• Original Assignee: Tyto Care, Ltd.
• Inventors: Dubin, Uri, Lachmanovich, Elad, Danon, Dov, Bychkov, Eyal
• Primary Examiner(s): Shin, Soo
• Application Number:
  US15/332,090
• Publication Number:
  US 20170112439A1
• Time in Patent Office: 869 Days
• Field of Search: None
• CPC Class Codes: A61B 2576/00 Medical imaging apparatus involving image processing or analysis A61B1/00009, A61B6/52 and A61B8/52 take precedence; image processing per se G06T; details of algorithms for analysing medical images G06T7/0012
• CPC Class Codes: A61B 5/0013 Medical image data A61B1/00011, A61B6/56, A61B8/56 take precedence
• CPC Class Codes: A61B 5/0077 Devices for viewing the surface of the body, e.g. camera, magnifying lens
• CPC Class Codes: A61B 5/026 Measuring blood flow A61B3/1233, A61B3/1241 take precedence
• CPC Class Codes: A61B 5/061 Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body A61B1/00158 takes precedence
• CPC Class Codes: A61B 5/684 Indicating the position of the sensor on the body
• CPC Class Codes: A61B 5/7285 for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal A61B6/5205, A61B6/541, A61B8/5207, A61B8/543 take precedence
• CPC Class Codes: A61B 5/743 Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: A61B 7/003 Detecting lung or respiration noise
• CPC Class Codes: A61B 7/04 Electric stethoscopes microphones, acoustic transducers therefor H04R
• CPC Class Codes: A61B 8/14 Echo-tomography
• CPC Class Codes: A61B 8/4416 related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions
• CPC Class Codes: A61B 8/4427 Device being portable or laptop-like
• CPC Class Codes: G16H 30/20 for handling medical images, e.g. DICOM, HL7 or PACS
• CPC Class Codes: G16H 30/40 for processing medical images, e.g. editing
• CPC Class Codes: G16H 40/63 for local operation

Abstract

A system for measuring physiological parameters, including: a portable measurement system, operable to acquire physiological measurement from an examined body location; an external camera operable to capture visible light, oriented toward the examined body location; a synchronization module, operable to receive a triggering indication, and in response to the triggering indication to associate to the physiological measurement a positioning image captured by the camera, the positioning image including at least a part of the portable measurement system adjacent to the examined body location; and a communication module operable to obtain the physiological measurement and the positioning image, and to transmit to a remote system: a physiological measurement record based on the physiological measurement, an orientation image based on the positioning image, and including at least a part of the portable measurement system adjacent to the examined body location, and association data associating the orientation image and the physiological measurement record.

Claims

1. A system for measuring physiological parameters of a patient, the system comprising:

a portable measurement system, operable to acquire physiological measurement from an examined body location of the patient;

an external camera, external to the portable measurement system, movable irrespective of the portable measurement system, and operable to capture visible light, oriented toward the examined body location;

a synchronization module, operable to receive a triggering indication, and in response to the triggering indication to associate to the physiological measurement a positioning image captured by the external camera, the positioning image comprising at least a part of the portable measurement system adjacent to the examined body location; and

a communication module operable to obtain the physiological measurement and the positioning image, and to transmit to a remote system;

a physiological measurement record which is based on the physiological measurement,

an orientation image which is based on the positioning image, the orientation image comprising at least a part of the portable measurement system adjacent to the examined body location, and

association data associating the orientation image and the physiological measurement record.

2. The system according to claim 1, wherein the synchronization module is operable to trigger the measurement of the physiological measurement by the portable measurement system, and to control a creation of the positioning image.

3. The system according to claim 1, wherein the physiological measurement is a location sensitive physiological measurement whose medical interpretation necessitate information of location of measurement.

4. The system according to claim 1, wherein the portable measurement system comprises a microphone, operable to acquire the physiological measurement which comprises internal sounds of a body of the patient.

5. The system according to claim 1, wherein the portable measurement system comprises an ultrasonic transducer which is operable to acquire the physiological measurement which comprises ultrasonic sound waves reflected from a body of the patient.

6. The system according to claim 1, wherein the portable measurement system comprises a blood flow sensor, operable to acquire the physiological measurement which is indicative of at least one blood flow parameter.

7. The system according to claim 1, wherein the synchronization module is integrated with the portable measurement system.

8. The system according to claim 1, further comprising a user interface which is operable to transmit to the synchronization module an interaction indication upon identification of a human interaction with the user interface which satisfy at least one predetermined interaction criterion, wherein the synchronization module is operable to trigger the measurement of the physiological measurement by the portable measurement system in response to the interaction indication.

9. The system according to claim 1, further comprising a monitor operable to display to a user positioning instructions indicating a body location for measurement.

10. The system according to claim 1, wherein the portable measurement system is operable to acquire physiological measurements from a plurality of examined body locations of the patient;

wherein the synchronization module is operable to associate to each physiological measurement out of the plurality of physiological measurements a corresponding positioning image captured by the external camera;

wherein the communication module is operable transmit to the remote system;

physiological measurement record corresponding to each physiological measurement out of the plurality measurements, a plurality of orientation images which are based on the positioning images, and association data associating each orientation image and the corresponding physiological measurement record.

11. The system according to claim 1, wherein the synchronization module is operable to receive multiple triggering indications during a continuous physiological examination, and in response to each of the multiple triggering indications to associate a positioning image to the physiological measurement measured during the continuous physiological examination.

12. The system according to claim 1, wherein the positioning image is selected from a sequence of images captured by the external camera comprising a plurality of images.

13. The system according to claim 1, further comprising an image processing module, operable to:

(a) obtain navigation data collected by the portable measurement system, and navigation data indicative of movement of the portable measurement system in time;

(b) process the navigation data and image data captured by the external camera at a first time, to determine an assessed location of the portable measurement at a second time in which the portable measurement system is hidden from the external camera; and

(c) generate an estimated orientation image on which the assessed location is indicated, based on an image captured by the external camera;

wherein the synchronization module is operable to associate to the estimated orientation image the physiological measurement acquired at the second time;

wherein the communication module is operable to transmit to the remote system;

(a) a second physiological measurement record which is based on the physiological measurement acquired at the second time, (b) the estimated orientation image, and (c) association data associating the estimated orientation image and the second physiological measurement record.

14. The system according to claim 1, comprising an image processing module which is operable to process the positioning image to provide the orientation image, wherein the processing comprises anonymizing the orientation image for removing identifiable visual information from the orientation image.

15. The system according to claim 1, comprising an image processing module which is operable to process at least one image acquired by the external camera to determine whether a location of the portable measurement system in the at least one image with respect to a predetermined location fulfils a proximity criterion;

and a processor operable to selectively trigger collection of the physiological measurement measured by the portable measurement system, upon a condition in which the location fulfils the proximity criterion.

16. The system according to claim 1, further comprising an image processing module operable to process the positioning image to identify a location of the portable positioning system within the positioning image, wherein the communication module is operable to transmit to the remote system information indicative of the location of the portable positioning system within the positioning image.

17. A physiological monitoring system, the system comprising:

a communication module operable to receive;

a plurality of physiological measurement records of a plurality of physiological measurements acquired by a portable measurement system at different positions of the portable measurement system with respect to a body of a patient,

a plurality of visible light orientation images, acquired by an external camera, external to the portable measurement system and movable irrespective of the portable measurement system, each of the plurality of visible light orientation images being indicative of a location of a portable measurement system with respect to the body of the patient, and

association data associating each orientation image with a corresponding physiological measurement record out of the plurality of physiological measurement records;

a processor, operable to process the association data and to retrieve from a physiological measurements database, based on results of the processing;

(a) a selected physiological measurement record and (b) at least one matching orientation image; and

a user interface output configured to display the at least one matching orientation image in combination with providing information of the selected physiological measurement record.

18. The physiological monitoring system according to claim 17, wherein the physiological measurements are location sensitive physiological measurements whose medical interpretation necessitate information of location of measurement.

19. The physiological monitoring system according to claim 17, wherein the user interface output is configured to display a plurality of orientation images associated with different physiological measurement records;

wherein the physiological monitoring system further comprises a user interface input for receiving a selection indication, indicative of an orientation image out of the plurality of orientation images;

wherein the processor is operable to retrieve the selected physiological measurement records based on the selection indication.

20. The physiological monitoring system according to claim 17, wherein the user interface output is configured to display identifiers of a plurality of physiological measurement records;

wherein the physiological monitoring system further comprises a user interface input for receiving a selection indication, indicative of physiological measurement record out of the plurality of physiological measurement records;

wherein the processor is operable to retrieve the selected physiological measurement records based on the selection indication.

21. The physiological monitoring system according to claim 17, wherein the user interface output is operable to display a video which comprises the plurality of orientation images, wherein the processor is operable to retrieve from the physiological measurements database the physiological measurement records, and to synchronize providing information of the different physiological measurement records with the displaying of the video, based on the association data.

22. The physiological monitoring system according to claim 17, wherein the communication module receives the plurality of physiological measurement records, the plurality of visible light orientation images and the association data from a remote system which comprises:

a portable measurement system which acquires the physiological measurement and a camera external to the portable measurement system which acquired images of the body of the patient;

wherein the physiological monitoring system further comprises a user interface configured to;

(a) display a reference image of the body of the patient acquired by the camera, and (b) obtain user inputs indicating a plurality of user-selected locations on the reference image;

wherein the communication module is operable to transmit to the remote system information indicative of the user-selected locations;

wherein the plurality of physiological measurements are acquired at different positions which are determined by the remote system based on the user-selected location.

23. A system for measuring physiological parameters of a patient, the system comprising:

a portable measurement system, operable to acquire physiological measurement of the patient;

an external camera, external to the portable measurement system, movable irrespective of the portable measurement system, and operable to capture visible light images of the body of the patient;

a processor, operable to;

process at least one image acquired by the external camera to determine a location of the portable measurement system in the image; and

initiate a change in the physiological measurement of the portable measurement system upon a condition in which the location fulfils a proximity criterion with respect to a predetermined examination location.

24. The system according to claim 23, wherein the processor is operable to cause the portable measurement system to start the physiological measurement, upon the condition in which the location fulfils the proximity criterion.

25. The system according to claim 23, wherein the processor is operable to cause initiation of collection of data of the physiological measurement, upon the condition in which the location fulfils the proximity criterion.

26. The system according to claim 23, wherein the processor is operable to cause the portable measurement system to change a physiological measurement parameter, upon the condition in which the location fulfils the proximity criterion.

27. The system according to claim 23, wherein the processor is operable to cause a user interface to present an instruction to the user to modify the location of the portable measurement system, upon the condition in which the location fulfils the proximity criterion.

28. A system for controlling measuring of physiological parameters of a patient, the system comprising:

a communication interface operable to receive at least one examination location, wherein the at least one examination location is defined with respect to a reference image which comprises at least a part of a body of a patient;

a processor, operable to process the at least one examination location, and to determine positioning parameters for a portable measurement system based on a result of the processing; and

a controller, operable to control execution of a physiological measurement of the patient by the portable measurement system, based on the positioning parameters;

wherein the reference image is a visible light image acquired by an external camera which is external to the portable measurement system and movable irrespective of the portable measurement system.

29. The system according to claim 28, wherein the at least one examination location is marked by a person on the reference image.

30. The system according to claim 28, wherein the controller is operable to control the execution of the physiological measurement based on the positioning parameters and on the reference image.

31. The system according to claim 28, wherein the processor is operable to determine different positioning parameters based on a plurality of examination locations marked on the reference image by at least one person, wherein the controller is operable to control execution of a plurality of physiological measurements of the patient by the portable measurement system based on the different positioning parameters, and to control breaks between the plurality of physiological measurements based on the different positioning parameters.

32. The system according to claim 28, wherein the controller is operable to control initiation of the physiological measurement based on the positioning parameters.

33. The system according to claim 28, wherein the controller is operable to control initiation of collection of data of the physiological measurement based on the positioning parameters.

34. The system according to claim 28, wherein the controller is operable to control changing of a physiological measurement parameter of the portable measurement system.

35. The system according to claim 28, wherein the controller is operable to control presentation of a user interface instruction to the user to modify the location of the portable measurement system.

36. The system according to claim 28, wherein the processor is further operable to process at least one visible light image showing the body of the patient and the portable measurement system which is acquired by the external camera after the determination of the positioning parameters, to determine a location of the portable measurement system in the at least one image;

wherein the controller is operable to control initiation of a new phase of a physiological measurement of the patient by the portable measurement system, upon a condition in which the location fulfils a proximity criterion with respect to a predetermined examination location.

37. A method for measuring physiological parameters of a patient, the method comprising:

associating a positioning image to a physiological measurement acquired from an examined body location of the patient by a portable measurement system;

the positioning image being an image captured by an external visible light camera, external to the portable measurement system and movable irrespective of the portable measurement system, the external visible light camera being oriented toward the examined body location, which comprises at least part of the portable measurement system adjacent to the examined body location; and

transmitting to a remote system;

a physiological measurement record which is based on the physiological measurement, an orientation image which is based on the positioning image and which comprises at least part of the portable measurement system adjacent to the examined body location, and association data associating the orientation image and the physiological measurement record.

38. The method according to claim 37, wherein the physiological measurement is a location sensitive physiological measurement whose medical interpretation necessitate information of location of measurement.

39. The method according to claim 37, further comprising acquiring the physiological measurement from the examined body location by the portable measurement system.

40. The method according to claim 37, wherein the physiological measurement comprises sounds of at least one lung of the patient.

41. The method according to claim 37, wherein the physiological measurement comprises ultrasonic sound waves reflected from a body of the patient.

42. The method according to claim 37, wherein the physiological measurement which is indicative of at least one blood flow parameter.

43. The method according to claim 37, further comprising selectively triggering the measurement of the physiological measurement by the portable measurement system in response to a user input which satisfy at least one predetermined interaction criterion.

44. The method according to claim 37, further comprising providing, via a user interface, positioning instructions indicating a body location for measurement.

45. The method according to claim 37, comprising:

acquiring physiological measurements from a plurality of examined body locations of the patient;

associating to each physiological measurement out of the plurality of physiological measurements a corresponding positioning image captured by the external camera; and

transmitting to the remote system;

(a) physiological measurement record corresponding to each physiological measurement out of the plurality measurements, (b) a plurality of orientation images which are based on the positioning images, and (c) association data associating each orientation image and the corresponding physiological measurement record.

46. The method according to claim 37, comprising selecting the positioning image out of a sequence of images captured by the external camera, the sequence comprising a plurality of images.

47. The method according to claim 37, comprising:

obtaining navigation data collected by the portable measurement system, the navigation data indicative of movement of the portable measurement system in time;

processing the navigation data and image data captured by the external camera at a first time, to determine an assessed location of the portable measurement at a second time in which the portable measurement system is hidden from the external camera;

and transmitting to the remote system an image captured by the external camera on which the assessed location is indicated.

48. The method according to claim 37, wherein the transmitting is preceded by processing the positioning image to provide the orientation image, wherein the processing comprises anonymizing the orientation image for removing identifiable visual information from the orientation image.

49. The method according to claim 37, comprising:

processing at least one image acquired by the external camera to determine whether a location of the portable measurement system in the at least one image with respect to a predetermined location fulfils a proximity criterion; and

selectively triggering a collection of the physiological measurement measured by the portable measurement system, upon a condition in which the location fulfils the proximity criterion.

50. The method according to claim 37, further comprising processing the positioning image to identify a location of the portable positioning system within the positioning image, wherein the transmitting further comprises transmitting to the remote system information indicative of the location of the portable positioning system within the positioning image.

51. A computer-implemented method for physiological monitoring, the method comprising:

receiving;

a plurality of physiological measurement records of a plurality of physiological measurements acquired by a portable measurement system at different positions of the portable measurement system with respect to a body of a patient,

a plurality of visible light orientation images, acquired by an external camera, external to the portable measurement system and movable irrespective of the portable measurement system, each of the plurality of orientation images being indicative of a location of a portable measurement system with respect to the body of the patient, and

association data associating each orientation image with a corresponding physiological measurement record out of the plurality of physiological measurement records;

storing on a tangible memory;

the plurality of physiological measurement records, the plurality of orientation images, and the association data;

based on the association data, retrieving from the tangible memory a selected physiological measurement record and at least one matching orientation image; and

displaying the at least one matching orientation image in combination with providing information of the selected physiological measurement record.

52. The method according to claim 51, comprising displaying a plurality of orientation images associated with different physiological measurement records;

receiving a selection indication indicative of a selection by a user of at least one out of the plurality of orientation images; and

retrieving the selected physiological measurement records based on the selection indication.

53. The method according to claim 51, comprising displaying identifiers of a plurality of physiological measurement records;

receiving a selection indication indicative of selection by a user of a physiological measurement record out of the plurality of physiological measurement records; and

retrieving the selected physiological measurement records based on the selection indication.

54. The method according to claim 51, comprising displaying a video which comprises the plurality of orientation images, retrieving from the tangible memory the physiological measurement records, and synchronizing providing information of the different physiological measurement records with the displaying of the video, based on the association data.

55. The method according to claim 51, wherein the receiving comprises receiving the plurality of physiological measurement records, the plurality of visible light orientation images and the association data from a remote system which comprises a portable measurement system which acquires the physiological measurement and a camera external to the portable measurement system which acquired images of the body of the patient;

wherein the receiving is preceded by;

displaying on a user interface a reference image of the body of the patient acquired by the camera;

obtaining user inputs indicating a plurality of user-selected locations on the reference image;

transmitting to the remote system information indicative of the user-selected locations;

wherein the plurality of physiological measurements are acquired at different positions which are determined by the remote system based on the user-selected location.

56. A computer-implemented method for physiological monitoring, the method comprising:

processing at least one visible light image showing a body of a patient and a portable measurement system to determine a location of the portable measurement system in the at least one image, wherein the visible light image is acquired by an external camera, external to the portable measurement system and movable irrespective of the portable measurement system; and

initiating a new phase of a physiological measurement of the patient by the portable measurement system, upon a condition in which the location fulfils a proximity criterion with respect to a predetermined examination location.

57. The method according to claim 56, wherein the initiating comprises starting the physiological measurement.

58. The method according to claim 56, wherein the initiating comprises initiating collection of data of the physiological measurement.

59. The method according to claim 56, wherein the initiating comprises changing a physiological measurement parameter of the portable measurement system.

60. The method according to claim 56, wherein the initiating comprises initiating presentation of a user interface instruction to the user to modify the location of the portable measurement system.

61. A computer-implemented method for physiological monitoring, the method comprising:

obtaining at least one examination location which is defined with respect to a reference image which comprises at least a part of a body of a patient;

determining positioning parameters for a portable measurement system, based on the at least one examination location; and

controlling execution of a physiological measurement of the patient by the portable measurement system, based on the positioning parameters;

wherein the reference image is a visible light image acquired by an external camera external to the portable measurement system and movable irrespective of the portable measurement system.

62. The method according to claim 61, wherein the at least one examination location is marked by a person on the reference image.

63. The method according to claim 61, wherein the controlling is further based on the reference image.

64. The method according to claim 61, wherein the obtaining comprises obtaining a plurality of examination locations marked by at least one person, wherein the determining comprises determining different positioning parameters based on the different examination locations, wherein the controlling comprises controlling execution of a plurality of physiological measurements of the patient by the portable measurement system, wherein the method further comprises controlling breaks between the plurality of physiological measurements based on the different positioning parameters.

65. The method according to claim 61, wherein the controlling comprises controlling initiation of the physiological measurement.

66. The method according to claim 61, wherein the controlling comprises initiating collection of data of the physiological measurement.

67. The method according to claim 61, wherein the controlling comprises changing a physiological measurement parameter of the portable measurement system.

68. The method according to claim 61, wherein the controlling comprises controlling presentation of a user interface instruction to the user to modify the location of the portable measurement system.

69. The method according to claim 61, wherein the controlling comprises processing at least one visible light image, acquired by the external camera after the determining, the at least one visible image showing the body of the patient and the portable measurement system to determine a location of the portable measurement system in the at least one image;

wherein the controlling comprises initiating a new phase of a physiological measurement of the patient by the portable measurement system, upon a condition in which the location fulfils a proximity criterion with respect to a predetermined examination location.

70. A non-transitory computer-readable medium for physiological monitoring, comprising instructions stored thereon, that when executed on a processor, perform the steps of:

obtaining;

a plurality of physiological measurement records of a plurality of physiological measurements acquired by a portable measurement system at different positions of the portable measurement system with respect to a body of a patient,

a plurality of visible light orientation images, acquired by an external camera, external to the portable measurement system and movable irrespective of the portable measurement system, each of the plurality of orientation images being indicative of a location of a portable measurement system with respect to the body of the patient, and

association data associating each orientation image with a corresponding physiological measurement record out of the plurality of physiological measurement records;

storing on a tangible memory;

the plurality of physiological measurement records, the plurality of orientation images, and the association data;

based on the association data, retrieving from the tangible memory a selected physiological measurement record and at least one matching orientation image; and

displaying the at least one matching orientation image in combination with providing information of the selected physiological measurement record.