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Methods for treating depressive symptoms

  • US 10,231,963 B2
  • Filed: 04/17/2017
  • Issued: 03/19/2019
  • Est. Priority Date: 05/24/2013
  • Status: Active Grant
First Claim
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1. A method of treating a depressive symptom in a subject in need thereof, the method comprising administering to the subject an effective amount of a p opioid receptor agonist that exhibits an Emax of 5% to 45% in a GTPγ

  • S binding assay wherein the depressive symptom is depressed mood, loss of pleasure, loss of appetite, sleep disturbance, psychomotor changes, fatigue, and/or post-partum depression.

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