Pharmacy formulation production system and pharmacy formulation production method for producing pharmaceutical individual formulations

• US 10,239,030 B2
• Filed: 04/29/2015
• Issued: 03/26/2019
• Est. Priority Date: 04/29/2014
• Status: Active Grant

• Current Assignee: Gako Deutschland GmbH
• Original Assignee: Gako International GmbH
• Inventors: Konietzko, Matthias
• Primary Examiner(s): Soohoo, Tony G
• Application Number:
  US15/307,651
• Publication Number:
  US 20170050157A1
• Time in Patent Office: 1,427 Days
• CPC Class Codes: A61J 3/00 Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
• CPC Class Codes: B01F 2101/22 Mixing of ingredients for pharmaceutical or medical compositions
• CPC Class Codes: B01F 27/805 wherein the stirrers or the receptacles are moved in order to bring them into operative position; Means for fixing the receptacle
• CPC Class Codes: B01F 33/80 Mixing plants; Combinations of mixers
• CPC Class Codes: B01F 33/846 using stored recipes for determining the composition of the mixture to be produced, i.e. for determining the amounts of the basic components to be dispensed from the component receptacles
• CPC Class Codes: B01F 33/848 using data, i.e. barcodes, 3D codes or similar type of tagging information, as instruction or identification codes for controlling the dispensing and mixing operations
• CPC Class Codes: B01F 35/832 Flow control by weighing
• CPC Class Codes: B01F 35/881 by weighing, e.g. with automatic discharge
• CPC Class Codes: G06Q 10/0875 Itemisation or classification of parts, supplies or services, e.g. bill of materials

Abstract

A pharmacy formulation preparation system (2) for preparing individual pharmaceutical formulations such as formulations for ointments, semisolid preparations, eye drops, lotions, pills, capsules or teas in quantities of up to 5 kg, according to the invention comprises: reading means (8); weighing means (12); mixing means (14), in particular a stirrer having a drive and a mixing container; display means (10); a data processing unit (4) adapted to have access to data in a pharmacy-associated stock database area (6); a preparation database (18) comprising composition information; and that for the read-in individual prescription data of an individual prescription, by accessing the preparation database (18), the raw materials required for preparing the individual prescription and the respective quantities thereof as well as the time period, the processing devices and the procedure parameters of the mixing procedure can be determined.

Claims

1. A pharmacy formulation preparation system for preparing pharmaceutical individual formulations such as formulations for ointments, semisolid preparations, eye drops, lotions, pills, capsules or teas in quantities of up to 5 kg, comprising:

reading means for reading in the individual prescription data of an individual prescription;

weighing means for weighing the quantities of the raw materials required for a read-in individual prescription;

mixing means, wherein the mixing means is adapted as a mixing and stirring unit comprising fastening means for a container having an inner volume of 10 ml to 5000 ml, a lifting unit, a stirring stick and an electric motor for driving the stirring stick in a rotating manner, the stirring stick having a stirring instrument attached or attachable thereto;

display means;

a pharmacy-associated stock database area comprising raw material identification parameters of the pharmaceutical raw materials available in the pharmacy as well as for at least one raw material identification parameter, an associated raw material quantity parameter and comprising processing device identification parameters of the processing devices available in the pharmacy;

a preparation database comprising composition information, which allocates the respectively contained raw materials and the respective proportions thereof to a plurality of individual formulations, as well as preparation information, which comprises, for each contained individual formulation, preparation information such as processing devices, time period and procedure parameters of the raw materials to be mixed; and

a data processing unit, which is adapted;

to have access to data in the pharmacy-associated stock database area;

to have access to data in the preparation database; and

such that, by accessing the preparation database, the raw materials required for preparing the individual prescription and the respective quantities thereof as well as the time period, the processing devices and the procedure parameters of the mixing procedure can be determined for the read-in individual prescription data of the individual prescription;

determining whether the individual prescription can be prepared, by accessing the pharmacy-associated stock database area, by comparing the raw materials required for the preparation and the respective quantities thereof to the available raw materials; and

that, if the individual prescription can be prepared, processing instructions for preparing the individual formulation, containing the information about the required raw materials, the respective quantities thereof, the required processing devices as well as the time period and the procedure parameters of the mixing procedure, can be output to a user.

2. The pharmacy formulation preparation system according to claim 1, wherein the data processing unit is further adapted such that, if a required raw material is found to be no longer present or no longer present to a sufficient extent, a respective message can be output to a user or an electronic order message can be sent.

3. The pharmacy formulation preparation system according to claim 2, wherein the pharmacy-associated stock database area further comprises, for at least one raw material identification parameter, one associated raw material shelf-life parameter.

4. The pharmacy formulation preparation system according to claim 2, wherein the pharmacy-associated stock database area further comprises, for at least one raw material identification parameter, an allocated raw material preparation date and wherein the composition information of the preparation database comprises, for at least one raw material, an allocated shelf-life, and wherein the data processing means is further adapted such that by comparing the shelf-life to the raw material preparation date plus the current date for a raw material of the individual prescription, it can be determined whether this raw material can still be used and whether the individual formulation can be prepared.

5. The pharmacy prescription preparation system according to claim 4, wherein the data processing unit is further adapted such that, if a required raw material is found not to be usable anymore, a respective message can be output to a user or an electronic order message can be sent.

6. The pharmacy formulation preparation system according to claim 5, wherein the preparation database further comprises plausibility check information, in particular combinations of incompatible raw materials or raw materials incompatible with a certain person, or an indication of incompatible raw materials, and wherein the data processing unit is further adapted such that a plausibility check can be performed, in which the raw materials determined as required for the preparation and the respective quantities thereof can be compared to at least part of the plausibility check information.

7. The pharmacy formulation preparation system according to claim 6, wherein a labeling means is further provided, which is adapted such that information about the prepared individual formulation can be printed.

8. The pharmacy formulation preparation system according to claim 1, wherein the pharmacy-associated stock database area is part of a pharmacy-internal stock database or form a pharmacy-internal stock database and/or wherein the pharmacy-internal stock database is stored on a pharmacy-internal computer, especially on the computer that also contains the data processing unit.

9. The pharmacy formulation preparation system according to claim 8, wherein the pharmacy-associated stock database area is part of the preparation database.

10. The pharmacy formulation preparation system according to claim 9, wherein the preparation database is stored on a server, wherein the data processing unit accesses the server via a data connection.

11. An arrangement of a plurality of pharmacy formulation preparation systems according to claim 10, wherein the pharmacy formulation preparation systems, except for the preparation database, are provided separately from each other and wherein their data processing units are adapted to have access to data on a common preparation database comprising composition information, which allocates the respectively contained raw materials and the proportions thereof to a plurality of individual formulations, as well as preparation information, which comprises, for each contained individual formulation, preparation information about the processing devices, time period and procedure parameters of the raw materials to be mixed.