Concentration measurements with a mobile device

• US 10,241,107 B2
• Filed: 06/20/2014
• Issued: 03/26/2019
• Est. Priority Date: 06/21/2013
• Status: Active Grant

• Current Assignee: Sensirion AG (Sensirion Holding AG)
• Original Assignee: Sensirion AG (Sensirion Holding AG)
• Inventors: Burgi, Lukas, Mayer, Felix, Wehrli, Samuel
• Primary Examiner(s): Siefke, Samuel P
• Application Number:
  US14/311,013
• Publication Number:
  US 20140377877A1
• Time in Patent Office: 1,740 Days
• CPC Class Codes: G01N 33/0059 Avoiding interference of a gas with the gas to be measured
• CPC Class Codes: G01N 33/4972 Determining alcohol content for vehicle safety devices B60K28/06
• CPC Class Codes: G01N 33/4975 other than oxygen, carbon dioxide or alcohol, e.g. organic vapours
• CPC Class Codes: Y10T 436/182 Organic or sulfhydryl containing [e.g., mercaptan, hydrogen, sulfide, etc.]
• CPC Class Codes: Y10T 436/200833 Carbonyl, ether, aldehyde or ketone containing
• CPC Class Codes: Y10T 436/204165 Ethanol

Abstract

A portable electronic device comprises a chemical sensor that is sensitive to a concentration of a chemical analyte and at least two auxiliary sensors that are sensitive to parameters that are different from the concentration of the chemical analyte. The portable electronic device comprises a control device that receives signals from the chemical sensor and from the auxiliary sensors at a plurality of points in time distributed over a measurement period and correlates the time dependencies of these signals to obtain a corrected reading of the first chemical sensor. The portable electronic device may be employed for breath analysis.

Claims

1. A portable electronic device comprising:

a first chemical sensor that is sensitive to a concentration of at least one of a first chemical element and a first chemical compound, the first chemical sensor being a semiconductor sensor having a heated membrane, the first chemical sensor having a cross- sensitivity to at least one of a second chemical element and a second chemical compound;

a first auxiliary sensor that is sensitive to at least one first parameter that is different from the concentration of the at least one the first chemical element and the first chemical compound;

at least one second auxiliary sensor that is sensitive to at least one second parameter that is different from the concentration of the at least one the first chemical element and the first chemical compound and different from the first parameter; and

a control device configured to carry out the following steps;

receiving signals of the first chemical sensor at a plurality of points in time distributed over a measurement period;

receiving signals of the first auxiliary sensor at a plurality of points in time distributed over said measurement period;

receiving signals of the second auxiliary sensor at a plurality of points in time distributed over said measurement period;

correlating a time dependency of the signals or the first chemical sensor, a time dependency of the signals of the first auxiliary sensor and a time dependency of the signals of the second auxiliary sensor to determine a sub-period of the measurement period during which the signals of the first chemical sensor represent signals that are representative of a parameter of interest, and wherein the sub-period is determined such that at least one of a value of the first parameter and a value of the second parameter is above or below a threshold during the sub- period; and

determining a corrected reading of the first chemical sensor corresponding to the sub-period,

wherein the correlation of the time dependencies of the signals of the first chemical sensor and at least one of the first and second auxiliary sensors is carried out to correct for said cross-sensitivity.

7. The portable electronic device of claim 1, wherein the control device is configured to employ the time dependency of the signals of the second auxiliary sensor to correct for a cross-sensitivity of at least one of the first chemical sensor and of the first auxiliary sensor to an environmental parameter to which the second auxiliary sensor is sensitive.

8. The portable electronic device of claim 1, wherein the portable electronic device is configured to carry out breath analysis, wherein the first chemical sensor is sensitive to the concentration of ethanol, of a ketone or of a thiol, wherein the first auxiliary sensor is sensitive to a concentration of carbon dioxide, and wherein the second auxiliary sensor is sensitive to at least one of the following parameters:

humidity;

temperature;

mass flow;

noise;

movements of the portable electronic device; and

proximity of a user of the portable electronic device.

9. The portable electronic device of claim 1, wherein the portable electronic device is configured to carry out breath analysis so as to measure the presence of ethanol in a user'"'"'s breath, wherein the first chemical sensor is sensitive to a concentration of ethanol, wherein the first auxiliary sensor is sensitive to a concentration of carbon dioxide, and wherein the control device is configured to correlate the time dependencies of the signals of the first chemical sensor and the first auxiliary sensor to determine a sub-period of said measurement period during which the signals of the first chemical sensor represent alveolar air.

10. The portable electronic device of claim 1, wherein the portable electronic device is configured to carry out breath analysis so as to determine breath odor in a user'"'"'s breath, wherein the first chemical sensor is sensitive to the concentration of a thiol, wherein the first auxiliary sensor is sensitive to a concentration of carbon dioxide, and wherein the control device is configured to correlate the time dependencies of the signals of the first chemical sensor and the first auxiliary sensor to determine a sub-period of said measurement period during which the signals of the first chemical sensor represent upper respiratory air.

11. The portable electronic device of claim 1, wherein the first auxiliary sensor is a second chemical sensor that is sensitive to a concentration of at least one of the second chemical element and the second chemical compound that is different from the at least one of the first chemical element and the first chemical compound, and wherein each of the first chemical sensor and the first auxiliary sensor is a semiconductor sensor having a heated membrane.

12. The portable electronic device of claim 1, wherein the control device is configured to employ the time dependency of the signals of the second auxiliary sensor to correct for a cross-sensitivity of at least one of the first chemical sensor and of the first auxiliary sensor to an environmental parameter to which the second auxiliary sensor is sensitive.

13. The method of claim 1, wherein the time dependency of the signals of the second auxiliary sensor is employed to correct for a cross-sensitivity of at least one of the first chemical sensor and of the first auxiliary sensor to an environmental parameter to which the second auxiliary sensor is sensitive.

2. A method of analyzing a fluid sample with a portable electronic device comprising a first chemical sensor that is sensitive to a concentration of at least one of a first chemical element and a first chemical compound, the first chemical sensor being a semiconductor sensor having a heated membrane, the first chemical sensor having a cross-sensitivity to at least one of a second chemical element and a second chemical compound, a first auxiliary sensor that is sensitive to at least one first parameter that is different from the concentration of the at least one of the first chemical element and the first chemical compound, and at least one second auxiliary sensor that is sensitive to at least one second parameter that is different from the concentration of the at least one of the first chemical element and the first chemical compound and different from the first parameter, the method comprising:

receiving signals of the first chemical sensor at a plurality of points in time distributed over a measurement period;

receiving signals of the first auxiliary sensor at a plurality of points in time distributed over said measurement period;

receiving signals of the second auxiliary sensor at a plurality of points in time distributed over said measurement period;

correlating a time dependency of the signals of the first chemical sensor, a time dependency of the signals of the first auxiliary sensor and a time dependency of the signals of the second auxiliary sensor to determine a sub-period of said measurement period during which the signals of the first chemical sensor represent signals that are representative of a parameter of interest, and wherein the sub-period is determined such that at least one of a value of the first parameter and a value of the second parameter is above or below a threshold during the sub-period; and

determining a corrected reading of the first chemical sensor corresponding to the sub-period, wherein the time dependencies of the signals of the first chemical sensor and at least one of the first and second auxiliary sensors are correlated to correct for said cross-sensitivity.

3. The method of claim 2, wherein the method is a method for breath analysis, wherein the first chemical sensor is sensitive to the concentration of ethanol, of a ketone or of a thiol, wherein the first auxiliary sensor is sensitive to a concentration of carbon dioxide, and wherein the second auxiliary sensor is sensitive to at least one of the following parameters:

humidity;

temperature;

mass flow;

noise;

movements of the portable electronic device; and

proximity of a user of the portable electronic device.

4. The method of claim 2, wherein the signals of the first chemical sensor, the signals of the first auxiliary sensor, and the signals of the second auxiliary sensor are correlated at more than one particular point in time.

5. The method according to claim 2, wherein determining the corrected reading of the first chemical sensor corresponding to the sub-period comprises determining the corrected reading of the first chemical sensor based on a subset of the signals of the first chemical sensor that omits at least some of the signals of the first chemical sensor that were detected outside of the sub-period.

6. A computer program element containing computer program code that causes a portable electronic device comprising a first chemical sensor that is sensitive to a concentration of at least one of a first chemical element and a first chemical compound, the first chemical sensor being a semiconductor sensor having a heated membrane, the first chemical sensor having a cross-sensitivity to at least one of a second chemical element and a second chemical compound, a first auxiliary sensor that is sensitive to at least one first parameter that is different from the concentration of the at least one of the First chemical element and the first chemical compound, at least one second auxiliary sensor that is sensitive to at least one second parameter that is different from the concentration of the at least one of the first chemical element and the first chemical compound and different from the first parameter, and a control device programmed to carry out the following method:

receiving signals of the first chemical sensor at a plurality of points in time distributed over a measurement period;

receiving signals of the first auxiliary sensor at a plurality of points in time distributed over said measurement period;

receiving signals of the second auxiliary sensor at a plurality of points in time distributed over said measurement period;

correlating a time dependency of the signals of the first chemical sensor, a time dependency of the signals of the first auxiliary sensor and a time dependency of the signals of the second auxiliary sensor to determine a sub-period of the measurement period during which the signals of the first chemical sensor represent signals that are representative of a parameter of interest, and wherein the sub-period is determined such that at least one of a value of the first parameter and a value of the second parameter is above or below a threshold during the sub-period; and

determining a corrected reading of the first chemical sensor corresponding to the sub-period, wherein the time dependencies of the signals of the first chemical sensor and at least one of the first and second auxiliary sensors are correlated to correct for said cross-sensitivity.