Techniques for percutaneous mitral valve replacement and sealing
First Claim
Patent Images
1. Apparatus for use with a native valve of a heart of a subject, the apparatus comprising:
- an overtube, transluminally advanceable to the heart;
a prosthetic valve support, having a compressed state for delivery through the overtube to the heart, and an expanded state in which the valve support comprises;
a flat annular upstream support portion;
comprising a nitinol frame and a fabric disposed over the nitinol frame,having an inner perimeter defined by a free inner edge that defines an opening through the upstream support portion, andhaving an outer perimeter that is at least 10 percent greater than the inner perimeter; and
a plurality of anchors comprising at least a first anchor and a second anchor, each anchor of the plurality of anchors being configured to anchor to a respective commissure of the native valve; and
a prosthetic valve;
having a compressed state for transluminal delivery, andbeing intracorporeally couplable to the valve support by being expanded toward an expanded state of the prosthetic valve while disposed within the opening,wherein;
(i) the valve support is configured such that upon deployment of the valve support from a distal end of the overtube, the first anchor and the second anchor anchor the valve support to the commissures by moving away from each other and into the commissures,(ii) the first anchor and the second anchor are configured to anchor the valve support to the commissures by extending, from the upstream support portion, through the commissures to a ventricular side of the commissures, and(iii) the valve support is configured such that, when anchored by the anchors to the commissures, and before the prosthetic valve is coupled to the valve support, the valve support allows the native valve to continue to function.
2 Assignments
0 Petitions
Accused Products
Abstract
Apparatus for use at a native heart valve of a subject is described. For some applications, the apparatus comprises a prosthetic valve support, configured (a) to be implanted at the native valve, (b) to facilitate, at a first period, implantation at the native valve of a first prosthetic valve, and (c) to facilitate, at a second period, implantation at the native valve of a second prosthetic valve. Other embodiments are also described.
-
Citations
19 Claims
-
1. Apparatus for use with a native valve of a heart of a subject, the apparatus comprising:
-
an overtube, transluminally advanceable to the heart; a prosthetic valve support, having a compressed state for delivery through the overtube to the heart, and an expanded state in which the valve support comprises; a flat annular upstream support portion; comprising a nitinol frame and a fabric disposed over the nitinol frame, having an inner perimeter defined by a free inner edge that defines an opening through the upstream support portion, and having an outer perimeter that is at least 10 percent greater than the inner perimeter; and a plurality of anchors comprising at least a first anchor and a second anchor, each anchor of the plurality of anchors being configured to anchor to a respective commissure of the native valve; and a prosthetic valve; having a compressed state for transluminal delivery, and being intracorporeally couplable to the valve support by being expanded toward an expanded state of the prosthetic valve while disposed within the opening, wherein; (i) the valve support is configured such that upon deployment of the valve support from a distal end of the overtube, the first anchor and the second anchor anchor the valve support to the commissures by moving away from each other and into the commissures, (ii) the first anchor and the second anchor are configured to anchor the valve support to the commissures by extending, from the upstream support portion, through the commissures to a ventricular side of the commissures, and (iii) the valve support is configured such that, when anchored by the anchors to the commissures, and before the prosthetic valve is coupled to the valve support, the valve support allows the native valve to continue to function. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
-
-
18. A method for use at a native valve of a heart of a subject, the method comprising:
-
advancing an overtube to the heart; via the overtube, implanting at the native valve a prosthetic valve support that has (i) a compressed state for delivery through the overtube to the heart, and (ii) an expanded state in which the valve support includes; a flat annular upstream support portion; including a nitinol frame and a fabric disposed over the nitinol frame, having an inner perimeter defined by a free inner edge that defines an opening through the upstream support portion, and having an outer perimeter that is at least 10 percent greater than the inner perimeter; and a plurality of anchors including at least a first anchor and a second anchor, each anchor of the plurality of anchors being configured to anchor to a respective commissure of the native valve; and subsequently, implanting a prosthetic valve; having a compressed state for transluminal delivery, and being intracorporeally couplable to the valve support by being expanded toward an expanded state of the prosthetic valve while disposed within the opening, wherein implanting the prosthetic valve support comprises implanting the prosthetic valve support such that; (i) upon deployment of the valve support from a distal end of the overtube, the first anchor and the second anchor anchor the valve support to the commissures by moving away from each other and into the commissures, (ii) the first anchor and the second anchor anchor the valve support to the commissures by extending, from the upstream support portion, through the commissures to a ventricular side of the commissures, and (iii) before the prosthetic valve is coupled to the valve support, the valve support allows the native valve to continue to function.
-
-
19. Apparatus for use with a native valve of a heart of a subject, the apparatus comprising:
-
an overtube, transluminally advanceable to the heart; a prosthetic valve support, having a compressed state for delivery through the overtube to the heart, and an expanded state in which the valve support comprises; a flat annular upstream support portion; comprising a nitinol frame and a fabric disposed over the nitinol frame, having an inner perimeter defined by a free inner edge that defines an opening through the upstream support portion, and having an outer perimeter that is at least 10 percent greater than the inner perimeter; and a plurality of anchors comprising at least a first anchor and a second anchor, each anchor of the plurality of anchors being configured to anchor to a respective commissure of the native valve; and a prosthetic valve; having a compressed state for transluminal delivery, and being intracorporeally couplable to the valve support by being expanded toward an expanded state of the prosthetic valve while disposed within the opening, wherein the valve support is configured such that upon deployment of the valve support from a distal end of the overtube, the first anchor and the second anchor anchor the valve support to the commissures by moving away from each other and pressing radially outward into the commissures.
-
Specification