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Techniques for percutaneous mitral valve replacement and sealing

  • US 10,245,143 B2
  • Filed: 07/19/2016
  • Issued: 04/02/2019
  • Est. Priority Date: 08/05/2011
  • Status: Active Grant
First Claim
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1. Apparatus for use with a native valve of a heart of a subject, the apparatus comprising:

  • an overtube, transluminally advanceable to the heart;

    a prosthetic valve support, having a compressed state for delivery through the overtube to the heart, and an expanded state in which the valve support comprises;

    a flat annular upstream support portion;

    comprising a nitinol frame and a fabric disposed over the nitinol frame,having an inner perimeter defined by a free inner edge that defines an opening through the upstream support portion, andhaving an outer perimeter that is at least 10 percent greater than the inner perimeter; and

    a plurality of anchors comprising at least a first anchor and a second anchor, each anchor of the plurality of anchors being configured to anchor to a respective commissure of the native valve; and

    a prosthetic valve;

    having a compressed state for transluminal delivery, andbeing intracorporeally couplable to the valve support by being expanded toward an expanded state of the prosthetic valve while disposed within the opening,wherein;

    (i) the valve support is configured such that upon deployment of the valve support from a distal end of the overtube, the first anchor and the second anchor anchor the valve support to the commissures by moving away from each other and into the commissures,(ii) the first anchor and the second anchor are configured to anchor the valve support to the commissures by extending, from the upstream support portion, through the commissures to a ventricular side of the commissures, and(iii) the valve support is configured such that, when anchored by the anchors to the commissures, and before the prosthetic valve is coupled to the valve support, the valve support allows the native valve to continue to function.

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