Glucose sensor signal reliability analysis
First Claim
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1. A method comprising:
- obtaining a plurality of glucose sensor measurements at a glucose sensor over a time interval by receiving an electrical current generated by the glucose sensor during a time that the glucose sensor is in contact with a patient;
storing the plurality of glucose sensor measurements as sensor data in a memory; and
detecting a decrease in an ability of the glucose sensor to accurately reflect a glucose level in a fluid of the patient based, at least in part, on an application of one or more thresholds to one or more sensitivity metrics, at least one of said sensitivity metrics being based, at least in part, on said glucose sensor measurements,wherein at least one of the sensitivity metrics comprises a measurement of dispersion of a rate of change in the glucose sensor measurements over at least a portion of the time interval,wherein a value of the measurement of dispersion that reflects a greater degree of dispersion corresponds to a greater ability of the glucose sensor to accurately reflect the glucose level, and a value of the measurement of dispersion that reflects a smaller degree of dispersion corresponds to a lesser ability of the glucose sensor to accurately reflect the glucose level, andwherein the detecting the decrease in the ability of the glucose sensor, the application of the one or more thresholds to the one or more sensitivity metrics, and the measurement of dispersion of the rate of change in the glucose sensor measurements are performed by one or more processors.
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Abstract
Disclosed are methods, apparatuses, etc. for glucose sensor signal reliability analysis.
24 Citations
16 Claims
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1. A method comprising:
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obtaining a plurality of glucose sensor measurements at a glucose sensor over a time interval by receiving an electrical current generated by the glucose sensor during a time that the glucose sensor is in contact with a patient; storing the plurality of glucose sensor measurements as sensor data in a memory; and detecting a decrease in an ability of the glucose sensor to accurately reflect a glucose level in a fluid of the patient based, at least in part, on an application of one or more thresholds to one or more sensitivity metrics, at least one of said sensitivity metrics being based, at least in part, on said glucose sensor measurements, wherein at least one of the sensitivity metrics comprises a measurement of dispersion of a rate of change in the glucose sensor measurements over at least a portion of the time interval, wherein a value of the measurement of dispersion that reflects a greater degree of dispersion corresponds to a greater ability of the glucose sensor to accurately reflect the glucose level, and a value of the measurement of dispersion that reflects a smaller degree of dispersion corresponds to a lesser ability of the glucose sensor to accurately reflect the glucose level, and wherein the detecting the decrease in the ability of the glucose sensor, the application of the one or more thresholds to the one or more sensitivity metrics, and the measurement of dispersion of the rate of change in the glucose sensor measurements are performed by one or more processors. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A method comprising:
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obtaining a plurality of glucose sensor measurements at a glucose sensor over a time interval by receiving an electrical current generated by the glucose sensor during a time that the glucose sensor is in contact with a patient; storing the plurality of glucose sensor measurements as sensor data in a memory; defining a sequence of windows in time; for at least one of said windows, computing a dispersion of a rate of change in the glucose sensor measurements over at least one of the windows; and detecting a decrease in an ability of the glucose sensor to accurately reflect a glucose level in a fluid of the patient, based, at least in part, on an application of one or more thresholds to the computed dispersion, wherein a value of the computed dispersion that reflects a greater degree of dispersion corresponds to a greater ability of the glucose sensor to accurately reflect the glucose level, and a value of the computed dispersion that reflects a smaller degree of dispersion corresponds to a lesser ability of the glucose sensor to accurately reflect the glucose level, and wherein the the detecting the decrease in the ability of the glucose sensor, the application of the one or more thresholds to the computed dispersion, and the computing of the dispersion of the rate of change in the glucose sensor measurements are performed by one or more processors. - View Dependent Claims (9)
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10. An apparatus for use with a memory and with a patient having a fluid containing glucose, the apparatus comprising:
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a glucose sensor configured to obtain glucose sensor measurements responsive to a presence of glucose in a fluid; and a processor configured to; store the plurality of glucose sensor measurements as sensor data in the memory; and detect a decrease in an ability of the glucose sensor to accurately reflect a glucose level in the fluid of the patient based, at least in part, on an application of one or more thresholds to one or more sensitivity metrics, at least one of said sensitivity metrics being based, at least part, on said glucose sensor measurements, wherein at least one of the sensitivity metrics comprises a measurement of dispersion of a rate of change in the glucose sensor measurements, and wherein a value of the measurement of dispersion that reflects a greater degree of dispersion corresponds to a greater ability of the glucose sensor to accurately reflect the glucose level, and a value of the measurement of dispersion that reflects a smaller degree of dispersion corresponds to a lesser ability of the glucose sensor to accurately reflect the glucose level. - View Dependent Claims (11)
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12. An apparatus for use with a memory and with a patient having a fluid containing glucose, the apparatus comprising:
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a glucose sensor configured to obtain glucose sensor measurements responsive to a presence of glucose in a fluid; and a processor configured to; store the plurality of glucose sensor measurements as sensor data in the memory; define a sequence of windows in time; for at least one of said windows, compute a measure of dispersion of a rate of change in the glucose sensor measurements over at least one of the windows; and detect a decrease in an ability of the glucose sensor to accurately reflect a glucose level in the fluid of the patient based, at least in part, on an application of one or more thresholds to the computed dispersion, wherein a value of the computed dispersion that reflects a greater degree of dispersion corresponds to a greater ability of the glucose sensor to accurately reflect the glucose level, and a value of the computed dispersion that reflects a smaller degree of dispersion corresponds to a lesser ability of the glucose sensor to accurately reflect the glucose level.
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13. An article for use with a glucose sensor, for use with a memory and for use with a patient having a fluid containing glucose, the article comprising:
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a non-transitory storage medium having machine-readable instructions stored thereon which are executable by a special purpose computing apparatus to; initiate reception of a plurality of glucose sensor measurements from the glucose sensor over a time interval; store the plurality of glucose sensor measurements as sensor data in the memory; and detect a decrease in an ability of the glucose sensor to accurately reflect a glucose level in the fluid of the patient based, at least in part, on an application of one or more thresholds to one or more sensitivity metrics, at least one of said sensitivity metrics being based, at least in part, on said glucose sensor measurements, wherein at least one of the sensitivity metrics comprises a measurement of dispersion of a rate of change in the glucose sensor measurements over at least a portion of the time interval, and wherein a value of the measurement of dispersion that reflects a greater degree of dispersion corresponds to a greater ability of the glucose sensor to accurately reflect the glucose level, and a value of the measurement of dispersion that reflects a smaller degree of dispersion corresponds to a lesser ability of the glucose sensor to accurately reflect the glucose level. - View Dependent Claims (14)
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15. An article for use with a glucose sensor, for use with a memory and for use with a patient having a fluid containing glucose, the article comprising:
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a non-transitory storage medium having machine-readable instructions stored thereon which are executable by a special purpose computing apparatus to; initiate reception of a plurality of glucose sensor measurements from the glucose sensor over a time interval; store the plurality of glucose sensor measurements as sensor data in the memory; define a sequence of windows in time; for at least one of said windows, compute a measure of dispersion of a rate of change in the glucose sensor measurements over at least one of the windows; and detect a decrease in an ability of the glucose sensor to accurately reflect a glucose level in the fluid of the patient based, at least in part, on an application of one or more thresholds to the computed dispersion, wherein a value of the computed dispersion that reflects a greater degree of dispersion corresponds to a greater ability of the glucose sensor to accurately reflect the glucose level, and a value of the computed dispersion that reflects a smaller degree of dispersion corresponds to a lesser ability of the glucose sensor to accurately reflect the glucose level.
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16. An apparatus for use with a glucose sensor, and for use with a memory and with a patient having a fluid containing glucose, the apparatus comprising:
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means for obtaining a plurality of glucose sensor measurements at the glucose sensor over a time interval; means for storing the plurality of glucose sensor measurements as sensor data in the memory; and means for detecting a decrease in an ability of the glucose sensor to accurately reflect a glucose level in the fluid of the patient, based, at least in part, on an application of one or more thresholds to one or more sensitivity metrics, at least one of said sensitivity metrics being based, at least in part, on said glucose sensor measurements, wherein at least one of the sensitivity metrics comprises a measurement of dispersion of a rate of change in the glucose sensor measurements over at least a portion of the time interval, and wherein a value of the measurement of dispersion that reflects a greater degree of dispersion corresponds to a greater ability of the glucose sensor to accurately reflect the glucose level, and a value of the measurement of dispersion that reflects a smaller degree of dispersion corresponds to a lesser ability of the glucose sensor to accurately reflect the glucose level.
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Specification