Vaccination delivery system and method

• US 10,252,043 B2
• Filed: 04/20/2017
• Issued: 04/09/2019
• Est. Priority Date: 04/21/2016
• Status: Active Grant

• Current Assignee: Mayo Foundation For Medical Education And Research (Mayo Clinic)
• Original Assignee: Mayo Foundation For Medical Education And Research (Mayo Clinic)
• Inventors: Chettiar, Kylash R., Rajesh, Vinutha
• Primary Examiner(s): Patel, Shefali D
• Application Number:
  US15/492,893
• Publication Number:
  US 20170304557A1
• Time in Patent Office: 719 Days
• CPC Class Codes: A61F 13/02 Adhesive bandages or dressings
• CPC Class Codes: A61M 2005/1583 Needle extractors
• CPC Class Codes: A61M 2005/1585 Needle inserters
• CPC Class Codes: A61M 2005/1586 Holding accessories for holding infusion needles on the body
• CPC Class Codes: A61M 2037/0023 Drug applicators using microneedles
• CPC Class Codes: A61M 2202/30 Vaccines
• CPC Class Codes: A61M 2205/0272 Electro-active or magneto-active materials
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/584 having a color code
• CPC Class Codes: A61M 2205/587 Lighting arrangements
• CPC Class Codes: A61M 2205/59 Aesthetic features, e.g. distraction means to prevent fears of child patients
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 2209/082 Mounting brackets, arm supports for equipment
• CPC Class Codes: A61M 2209/088 on the body
• CPC Class Codes: A61M 37/0015 by using microneedles
• CPC Class Codes: A61M 5/158 Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body

Abstract

A device can be used for delivering a dose of a vaccine, a medicine, a medication, a drug, or a prescription. For example, this document describes a wearable vaccination device that plays an audible sound or a musical tune for distracting or entertaining a patient while an intradermal vaccine is delivered via the patient'"'"'s skin. A control portion of the wearable vaccination device includes a processing unit, a rhythm producer that produces audible sounds to distract or entertain the patient, and an injection module that provides an intradermal injection using one or more microneedles.

Claims

1. A device for administering a vaccine intradermally, comprising:

a bracelet including a fastener for attaching the bracelet to a patient'"'"'s appendage;

a vaccination unit attached to the bracelet, the vaccination unit including;

a microneedle;

a set of electromagnets including a first electromagnet that is fixedly attached to the microneedle and a second electromagnet; and

a collapsible drug storage capsule disposed between the first and second electromagnets, wherein the first electromagnet is movable in relation to the second electromagnet to thereby cause a compression of the collapsible drug storage capsule that causes the vaccine in the collapsible drug storage capsule to eject from the microneedle;

an audio unit attached to the bracelet and including at least one microspeaker; and

a button attached to the bracelet for activating electrical signals to play an audible sound through the at least one microspeaker, and after a delay, to change relative polarity states of the set of electromagnets to cause the first electromagnet to move the microneedle to;

(i) pierce skin of the patient and (ii) administer the vaccine intradermally to the patient through the microneedle.

2. The device of claim 1, wherein the delay is one minute or less.

3. The device of claim 2, wherein the delay is fifteen seconds or less.

4. The device of claim 1, wherein the vaccine delivers a medically effective dose through the microneedle.

5. The device of claim 1, further comprising an adhesive sterilized bandage or a gauze removably affixed to the bracelet for application to the patient'"'"'s appendage on or over an area of penetration of the microneedle into the patient'"'"'s skin.

6. The device of claim 1, wherein the bracelet comprises a non-allergic bracelet.

7. The device of claim 1, further comprising third and fourth electromagnets.

8. The device of claim 1, wherein the bracelet is configured to be secured to the patient'"'"'s appendage by adhesives and an adjustable bracelet lock attached to the bracelet.

9. The device of claim 1, wherein the bracelet has one or more colors or graphic designs.

10. The device of claim 1, wherein the audible sound comprises one or more of musical tones, tunes, and songs.

11. The device of claim 1, wherein the device reduces a likelihood of needle stick injury.

12. The device of claim 1, wherein the device promotes patient compliance for receiving vaccines.

13. A vaccination platform for distracting a patient prior to medicine or drug delivery, comprising:

a bracelet for attachment to the patient'"'"'s appendage;

a vaccination unit located in a center portion of the bracelet, the vaccination unit comprising;

a processing unit;

a rhythm producer for producing audible sounds; and

an injection module including a first electromagnet, a second electromagnet, a microneedle, and a collapsible drug delivery capsule disposed between the first and second electromagnets, the microneedle affixed to the first electromagnet and having a proximal end communicating with the collapsible drug delivery capsule and a distal end to provide an intradermal vaccination to the patient, wherein the first electromagnet is movable in relation to the second electromagnet to thereby cause a compression of the collapsible drug delivery capsule that causes a vaccine in the collapsible drug delivery capsule to eject from the microneedle when relative polarity states of the first and second electromagnets are changed by the processing unit, wherein the processing unit controls a delay between a start of the audible sounds and when the vaccination occurs; and

a non-allergic adhesive located on the bracelet to secure the bracelet to the patient'"'"'s skin.

14. The vaccination platform of claim 13, wherein the bracelet further comprises a light configured to flash to indicate when the vaccination may occur.

15. The vaccination platform of claim 13, wherein the microneedle is a first microneedle, and further comprising one or more additional microneedles.

16. The vaccination platform of claim 13, further comprising third and fourth electromagnets.

17. The vaccination platform of claim 13, further comprising an adhesive sterilized bandage or a gauze removably affixed to the bracelet for application to the patient'"'"'s appendage on or over an area of penetration of the microneedle into the patient'"'"'s skin.