Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
First Claim
1. An automated antibiotic susceptibility testing (AST) quality control (QC) component, comprising:
- a frame including a plurality of wells;
at least one clip attached to the frame, wherein the at least one clip includes at least one clip that interacts with a reagent cartridge;
at least one microbial isolate in at least one of the plurality of wells; and
a means of identifying the component as an AST QC test by an automated system.
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Accused Products
Abstract
A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. The system also may quantify the relative abundance of viable microorganisms in a sample using dynamic dilution, and facilitate growth of microorganisms in customized media for rapid, accurate antimicrobial susceptibility testing. Automated quality control test components and methods of their use are also disclosed.
418 Citations
22 Claims
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1. An automated antibiotic susceptibility testing (AST) quality control (QC) component, comprising:
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a frame including a plurality of wells; at least one clip attached to the frame, wherein the at least one clip includes at least one clip that interacts with a reagent cartridge; at least one microbial isolate in at least one of the plurality of wells; and a means of identifying the component as an AST QC test by an automated system. - View Dependent Claims (2, 3, 4, 5, 6, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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7. An automated microbial identification (ID) quality control (QC) component, comprising
a frame including a plurality of wells; -
at least one clip attached to the frame; at least one target microbial nucleic acid molecule in at least one of the plurality of wells, wherein the microbial ID QC component is configured to interlock with an antibiotic susceptibility QC component; and a means of identifying the component as a microbial ID QC test by an automated system. - View Dependent Claims (8, 9, 10, 11)
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Specification