UV-absorbing vinylic monomers and uses thereof

• US 10,254,567 B2
• Filed: 02/16/2017
• Issued: 04/09/2019
• Est. Priority Date: 02/22/2016
• Status: Active Grant

• Current Assignee: Alcon Incorporated
• Original Assignee: Novartis Ag
• Inventors: Chang, Frank, DeSousa, Ryan, Holland, Troy Vernon, Pruitt, John Dallas, Nelson, Jared
• Primary Examiner(s): McClendon, Sanza L.
• Application Number:
  US15/434,105
• Publication Number:
  US 20170242275A1
• Time in Patent Office: 782 Days
• CPC Class Codes: B29D 11/00134 Curing of the contact lens material
• CPC Class Codes: B29K 2105/0002 monomers or prepolymers
• CPC Class Codes: C07C 233/38 having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
• CPC Class Codes: C07D 249/20 with aryl radicals directly attached in position 2
• CPC Class Codes: C08F 20/36 containing oxygen in addition to the carboxy oxygen , e.g. 2-N-morpholinoethyl (meth)acrylate or 2-isocyanatoethyl (meth)acrylate
• CPC Class Codes: C08F 220/603 and containing oxygen in addition to the carbonamido oxygen and nitrogen
• CPC Class Codes: C08F 220/70 Nitriles; Amides; Imides
• CPC Class Codes: G02B 1/043 Contact lenses
• CPC Class Codes: G02B 5/208 for use with infrared or ultraviolet radiation, e.g. for separating visible light from infrared and/or ultraviolet radiation
• CPC Class Codes: G02B 5/223 containing organic substances, e.g. dyes, inks or pigments
• CPC Class Codes: G02C 7/049 Contact lenses having special fitting or structural features achieved by special materials or material structures
• CPC Class Codes: G02C 7/108 Colouring materials

Abstract

Described herein are water-soluble UV-absorbing vinylic monomers and their uses in preparing UV-absorbing contact lenses capable of blocking ultra-violet (“UV”) radiation and optionally (but preferably) violet radiation with wavelengths from 380 nm to 440 nm, thereby protecting eyes to some extent from damages caused by UV radiation and potentially from violet radiation. This invention also provides a UV-absorbing contact lens.

Claims

1. A UV-absorbing vinylic monomer of any one of formula (I) to (VII)

2. The UV-absorbing vinylic monomer of claim 1, being a vinylic monomer of formula (IV) or (V).

3. The UV-absorbing vinylic monomer of claim 2, being selected from a vinylic monomer of any one of the following formula:

4. The UV-absorbing vinylic monomer of claim 1, being a vinylic monomer of formula (VI) or (VII).

5. The UV-absorbing vinylic monomer of claim 4, being selected from a vinylic monomer of any one of the following formula: