Integrated centrifugal blood pump-oxygenator, an extracorporeal life support system and a method of de-bubbling and priming an extracorporeal life support system
First Claim
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1. A method for pumping and oxygenating blood, the method including:
- receiving a flow of gas including oxygen into a gas inlet manifold via a gas inlet of a housing in which the gas inlet manifold is disposed;
passing the flow of gas from the gas inlet manifold to a gas outlet manifold disposed within the housing through an oxygenator assembly having an exterior surface and an interior surface forming an exterior surface of a blood outlet channel, the oxygenator assembly including a plurality of hollow fibers through which the gas outlet manifold is in fluid communication with the gas inlet manifold, the blood outlet channel being coaxial with the oxygenator assembly;
outputting the flow of gas from the gas outlet manifold via a gas outlet of the housing;
rotating an impeller to generate a flow of blood that flows through a blood inlet to a blood inlet channel, through the blood inlet channel to the exterior surface of the oxygenator assembly, from the exterior surface of the oxygenator assembly through the oxygenator assembly and the interior surface of the oxygenator assembly into the blood outlet channel, and through the blood outlet channel to a blood outlet;
transferring oxygen from the flow of gas to the flow of blood through the hollow fibers; and
transferring carbon dioxide from the flow of blood to the flow of gas through the hollow fibers.
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Abstract
A method for pumping and oxygenating blood includes receiving a flow of gas including oxygen into a gas inlet manifold via a gas inlet. The flow of gas is passed through the hollow fibers from the gas inlet manifold to a gas outlet manifold. The flow of gas is output from the gas outlet manifold via a gas outlet. An impeller is rotated to generate a flow of blood that flows over the hollow fibers. Oxygen from the flow of gas is transferred to the flow of blood through the hollow fibers. Carbon dioxide is transferred from the flow of blood to the flow of gas through the hollow fibers.
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Citations
20 Claims
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1. A method for pumping and oxygenating blood, the method including:
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receiving a flow of gas including oxygen into a gas inlet manifold via a gas inlet of a housing in which the gas inlet manifold is disposed; passing the flow of gas from the gas inlet manifold to a gas outlet manifold disposed within the housing through an oxygenator assembly having an exterior surface and an interior surface forming an exterior surface of a blood outlet channel, the oxygenator assembly including a plurality of hollow fibers through which the gas outlet manifold is in fluid communication with the gas inlet manifold, the blood outlet channel being coaxial with the oxygenator assembly; outputting the flow of gas from the gas outlet manifold via a gas outlet of the housing; rotating an impeller to generate a flow of blood that flows through a blood inlet to a blood inlet channel, through the blood inlet channel to the exterior surface of the oxygenator assembly, from the exterior surface of the oxygenator assembly through the oxygenator assembly and the interior surface of the oxygenator assembly into the blood outlet channel, and through the blood outlet channel to a blood outlet; transferring oxygen from the flow of gas to the flow of blood through the hollow fibers; and transferring carbon dioxide from the flow of blood to the flow of gas through the hollow fibers. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method for pumping and oxygenating blood, the method including:
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receiving a flow of gas including oxygen into a gas inlet manifold via a gas inlet of a housing in which the gas inlet manifold is disposed; passing the flow of gas from the gas inlet manifold to a gas outlet manifold disposed within the housing through an oxygenator assembly having an exterior surface and an interior surface forming an exterior surface of a blood outlet channel, the oxygenator assembly including a plurality of hollow fibers through which the gas outlet manifold is in fluid communication with the gas inlet manifold; outputting the flow of gas from the gas outlet manifold via a gas outlet of the housing; magnetically suspending an impeller in a contact-free manner with respect to the housing during rotation of the impeller; rotating the impeller to generate a flow of blood that flows through a blood inlet to a blood inlet channel, through the blood inlet channel to the exterior surface of the oxygenator assembly, from the exterior surface of the oxygenator assembly through the oxygenator assembly and the interior surface of the oxygenator assembly into the blood outlet channel, and through the blood outlet channel to a blood outlet; transferring oxygen from the flow of gas to the flow of blood through the hollow fibers; and transferring carbon dioxide from the flow of blood to the flow of gas through the hollow fibers. - View Dependent Claims (19)
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20. A method for pumping and oxygenating blood, the method including:
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receiving a flow of gas including oxygen into a gas inlet manifold via a gas inlet of a housing in which the gas inlet manifold is disposed; passing the flow of gas from the gas inlet manifold to a gas outlet manifold disposed within the housing through an oxygenator assembly having an exterior surface and an interior surface forming an exterior surface of a blood outlet channel, the oxygenator assembly including a plurality of hollow fibers through which the gas outlet manifold is in fluid communication with the gas inlet manifold, the plurality of hollow fibers being arranged circumferentially around the blood outlet channel; outputting the flow of gas from the gas outlet manifold via a gas outlet of the housing; rotating an impeller to generate a flow of blood that flows through a blood inlet to a blood inlet channel, through the blood inlet channel to the exterior surface of the oxygenator assembly, from the exterior surface of the oxygenator assembly through the oxygenator assembly and the interior surface of the oxygenator assembly into the blood outlet channel, and through the blood outlet channel to a blood outlet, wherein the blood inlet channel is surrounded by the blood outlet channel; transferring oxygen from the flow of gas to the flow of blood through the hollow fibers; and transferring carbon dioxide from the flow of blood to the flow of gas through the hollow fibers.
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Specification