DNA sequencing with non-fluorescent nucleotide reversible terminators and cleavable label modified nucleotide terminators
First Claim
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1. A method for determining the identity of each of a series of consecutive nucleotide residues in a nucleic acid comprising:
- a) contacting a plurality of the nucleic acids with (i) at least four different dideoxynucleotide analogues, each having the structure;
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Abstract
This invention provides a process for sequencing nucleic acids using 3′ modified deoxynucleotide analogs or 3′ modified deoxyinosine triphosphate analogs, and 3′ modified dideoxynucleotide analogs having a detectable marker attached to a base thereof.
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8 Claims
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1. A method for determining the identity of each of a series of consecutive nucleotide residues in a nucleic acid comprising:
a) contacting a plurality of the nucleic acids with (i) at least four different dideoxynucleotide analogues, each having the structure; - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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