Medical system for mapping cardiac tissue

• US 10,264,985 B2
• Filed: 10/01/2018
• Issued: 04/23/2019
• Est. Priority Date: 10/03/2014
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Laughner, Jacob I., Ricci, Carlos Alberto, Kovtun, Vladimir V., Shome, Shibaji, Thakur, Pramodsingh H., Shuros, Allan C., Stalsberg, Kevin J.
• Primary Examiner(s): Wehrheim, Lindsey G
• Application Number:
  US16/148,904
• Publication Number:
  US 20190029535A1
• Time in Patent Office: 204 Days
• CPC Class Codes: A61B 2505/05 Surgical care
• CPC Class Codes: A61B 5/0245 by using sensing means generating electric signals, i.e. ECG signals
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/347 Detecting the frequency distribution of signals
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61B 5/367 Electrophysiological study [EPS], e.g. electrical activation mapping or electro-anatomical mapping
• CPC Class Codes: A61B 5/6858 with a distal basket, e.g. expandable basket
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/725 using specific filters therefor, e.g. Kalman or adaptive filters A61B5/316 take precedence
• CPC Class Codes: A61B 5/7253 characterised by using transforms

Abstract

Medical devices and methods for making and using medical devices are disclosed. An example system for mapping the electrical activity of the heart includes a catheter shaft. The catheter shaft includes a plurality of electrodes including a first and a second electrode. The system also includes a processor. The processor is capable of collecting a first signal corresponding to a first electrode over a time period and generating a first time-frequency distribution corresponding to the first signal. The first time-frequency distribution includes a first dominant frequency value representation occurring at one or more first base frequencies. The processor is also capable of applying a filter to the first signal or derivatives thereof to determine whether the first dominant frequency value representation includes a single first dominant frequency value at a first base frequency or two or more first dominant frequency values at two or more base frequencies.

Claims

1. A system for mapping the electrical activity of the heart, the system comprising:

a catheter shaft, wherein a plurality of electrodes is coupled thereto;

a processor, wherein the processor is configured to;

receive a signal from a first electrode of the plurality of electrodes over a time period;

generate a time-frequency distribution corresponding to the signal, wherein the time-frequency distribution includes a dominant frequency value representation, wherein the dominant frequency representation includes one or more dominant frequency values occurring at one or more base frequencies;

modify the signal using one or more harmonic components of the signal or derivatives thereof to facilitate determining if the one or more dominant frequency values includes a single dominant frequency value or a plurality of dominant frequency values; and

determine if the one or more dominant frequency values includes a single dominant frequency value or a plurality of dominant frequency values.

2. The system of claim 1, wherein using the one or more harmonic components of the signal or derivatives thereof includes identifying frequency values at integer multiples of the one or more base frequencies, and wherein the frequency values corresponding to the integer multiples are added to the one or more dominant frequency values occurring at the one or more base frequencies.

3. The system of claim 2, wherein analyzing the modified signal includes comparing the magnitude of the dominant frequency values in the modified signal after the frequency values corresponding to the integer multiples of the one or more base frequencies are added to the one or more dominant frequency values occurring at the one or more base frequencies.

4. The system of claim 1, wherein analyzing the modified signal includes comparing the magnitude of the one or more dominant frequency values in the modified signal.

5. The system of claim 1, wherein the processor is configured to generate a visual display including at least one visual indicator corresponding to the signal or derivatives thereof.

6. The system of claim 1, wherein the processor is configured to generate a visual display including at least one sinusoid corresponding to the one or more base frequencies.

7. The system of claim 1, wherein the processor is configured to:

receive a second signal from a second electrode of the plurality of electrodes over the time period;

generate a second time-frequency distribution corresponding to the second signal, wherein the second time-frequency distribution includes a second dominant frequency value representation, wherein the second dominant frequency representation includes one or more second dominant frequency values occurring at one or more second base frequencies;

modify the second signal using one or more harmonic components of the second signal or derivatives thereof to facilitate determining if the one or more second dominant frequency values includes a single second dominant frequency value or a plurality of second dominant frequency values; and

determine if the one or more second dominant frequency values includes a single second dominant frequency value or a plurality of second dominant frequency values.

8. The system of claim 7, wherein the processor is configured to determine an attraction point, wherein the attraction point is defined when the one or more first dominant frequency values substantially relate to the one or more second dominant frequency values.

9. The system of claim 7, wherein the processor is configured to generate a visual display including at least one visual indicator corresponding to the second signal or derivatives thereof.

10. The system of claim 7, wherein the processor is configured to generate a visual display including at least one sinusoid corresponding to the one or more second base frequencies.

11. A method for mapping the electrical activity of the heart, the method comprising:

receiving a signal from a first electrode of a plurality of electrodes coupled to a catheter shaft over a time period;

generating a time-frequency distribution corresponding to the signal, wherein the time-frequency distribution includes a dominant frequency value representation, wherein the dominant frequency representation includes one or more dominant frequency values occurring at one or more base frequencies;

modifying the signal using one or more harmonic components of the signal or derivatives thereof to facilitate determining if the one or more dominant frequency values includes a single dominant frequency value or a plurality of dominant frequency values; and

determining if the one or more dominant frequency values includes a single dominant frequency value or a plurality of dominant frequency values.

12. The method of claim 11, wherein using the one or more harmonic components of the signal or derivatives thereof includes identifying frequency values at integer multiples of the one or more base frequencies, and wherein the frequency values corresponding to the integer multiples are added to the one or more dominant frequency values occurring at the one or more base frequencies.

13. The method of claim 12, wherein analyzing the modified signal includes comparing the magnitude of the dominant frequency values in the modified signal after the frequency values corresponding to the integer multiples of the one or more base frequencies are added to the one or more dominant frequency values occurring at the one or more base frequencies.

14. The method of claim 11, wherein analyzing the modified signal includes comparing the magnitude of the one or more dominant frequency values in the modified signal.

15. The method of claim 11, further comprising generating a visual display including at least one visual indicator corresponding to the signal or derivatives thereof.

16. The method of claim 11, further comprising generating a visual display including at least one sinusoid corresponding to the one or more base frequencies.

17. The method of claim 11, wherein the processor is configured to:

receiving a second signal from a second electrode of the plurality of electrodes over the time period;

generating a second time-frequency distribution corresponding to the second signal, wherein the second time-frequency distribution includes a second dominant frequency value representation, wherein the second dominant frequency representation includes one or more second dominant frequency values occurring at one or more second base frequencies;

modifying the second signal using one or more harmonic components of the second signal or derivatives thereof to facilitate determining if the one or more second dominant frequency values includes a single second dominant frequency value or a plurality of second dominant frequency values; and

determining if the one or more second dominant frequency values includes a single second dominant frequency value or a plurality of second dominant frequency values.

18. The method of claim 17, further comprising determining an attraction point, wherein the attraction point is defined when the one or more first dominant frequency values substantially relate to the one or more second dominant frequency values.

19. The method of claim 17, further comprising generating a visual display including at least one visual indicator corresponding to the second signal or derivatives thereof.

20. The method of claim 17, further comprising generating a visual display including at least one sinusoid corresponding to the one or more second base frequencies.