Apparatus and method for recording neural signals in the presence of artifacts
First Claim
1. A system for recording of electrical signals in the presence of artifacts, comprising:
- a stimulation electrode configured to introduce a stimulation signal;
a recording electrode configured to receive an electrical signal;
a blanking circuit electrically coupled to the recording electrode, the blanking circuit comprising a switch in parallel with a capacitor, wherein the switch effectively shorts the capacitor when closed;
an amplifier electrically coupled to the blanking circuit and configured to amplify the electrical signal, wherein the amplifier has a first gain when the switch is closed and a second gain lower than the first gain when the switch is open; and
a driver electrically coupled to the amplifier and configured to buffer the output of the amplifier, wherein;
the blanking circuit is located between the recording electrode and an input to the amplifier.
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Accused Products
Abstract
Systems and methods are disclosed herein for recording electrical signals in the presence of artifacts. The system and methods can employ multiple techniques for attenuating large, unwanted artifacts while preserving lower amplitude desirable signals. Aspects that can improve the recording of electrical signals in the presence of larger artifacts include particular electrode placement and spacing, high dynamic range amplification with good linearity, and signal blanking. Combinations of more or fewer techniques can be employed to achieve the desired attenuation of signal artifacts while preserving the desired signal. The systems and methods are suitable for recording neural signals in the presence of electrical stimulation signals.
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Citations
20 Claims
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1. A system for recording of electrical signals in the presence of artifacts, comprising:
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a stimulation electrode configured to introduce a stimulation signal; a recording electrode configured to receive an electrical signal; a blanking circuit electrically coupled to the recording electrode, the blanking circuit comprising a switch in parallel with a capacitor, wherein the switch effectively shorts the capacitor when closed; an amplifier electrically coupled to the blanking circuit and configured to amplify the electrical signal, wherein the amplifier has a first gain when the switch is closed and a second gain lower than the first gain when the switch is open; and a driver electrically coupled to the amplifier and configured to buffer the output of the amplifier, wherein; the blanking circuit is located between the recording electrode and an input to the amplifier. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method of recording of electrical signals in the presence of artifacts, comprising:
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emitting, by a stimulation electrode placed in proximity to a region of interest, a stimulation signal; receiving, by a recording electrode placed in proximity to the region of interest, an electrical signal responsive to the stimulation signal; amplifying, by an amplifier electrically coupled to the recording electrode, the electrical signal; reducing, by a blanking circuit electrically coupled to the amplifier, and located between an input to the amplifier and the recording electrode, a gain of the amplifier, the blanking circuit comprising a switch in parallel with a capacitor, wherein the switch effectively shorts the capacitor when closed, and wherein the amplifier has a first gain when the switch is closed and a second gain lower than the first gain when the switch is open; buffering, by a driver electrically coupled to the amplifier, the amplified signal; and recording the buffered signal. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification