Implant for influencing the blood flow in arteriovenous defects

• US 10,265,154 B2
• Filed: 09/07/2011
• Issued: 04/23/2019
• Est. Priority Date: 09/08/2010
• Status: Active Grant

• Current Assignee: Phenox Gmbh
• Original Assignee: Phenox Gmbh
• Inventors: Schneider, Manuel, Rolla, Stefan, Aporta, Carsten, Hannes, Ralf, Monstadt, Hermann
• Primary Examiner(s): Prebilic, Paul B
• Application Number:
  US13/821,350
• Publication Number:
  US 20130211492A1
• Time in Patent Office: 2,785 Days
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2002/9505 having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument
• CPC Class Codes: A61F 2002/9665 with additional retaining means
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2250/0043 differing in electric properties, e.g. in electrical conductivity, in galvanic properties
• CPC Class Codes: D04C 1/06 Braid or lace serving particular purposes
• CPC Class Codes: D10B 2509/06 Vascular grafts; stents

Abstract

A blood vessel implant to influence the flow of blood in the area of arteriovenous malformations. The implant has a wall of individual filaments forming a tubular braiding extending axially from the proximal to the distal end, the individual filaments crossing and forming points of intersection. The implant is deformable so that in an insertion catheter it is shaped so that its diameter is reduced and can be expanded at the implantation site adapting to the diameter of the blood vessel. The filament ends at the proximal and/or distal end of the braiding are each brought together at least in pairs and connected with each other permanently. The filament ends connect with each other and are shaped so as to be atraumatic The filaments cross at the points of intersection distally from the filament ends and are connected with each other at the proximal end of the implant.

Claims

1. An implant for blood vessels to influence the flow of blood in an implantation site comprising the area of arteriovenous malformations, said implant having proximal and distal ends and a wall comprising individual filaments forming a tubular braiding extending in axial direction from the proximal to the distal end, wherein

the individual filaments have ends at the proximal and/or distal end of the braiding and cross one another to form points of intersection, and wherein

the implant is deformable in such a manner that, when accommodated in an insertion catheter, it is shaped so that its diameter is reduced and can be expanded at the implantation site and adapt to the diameter of the blood vessel into which it is inserted, and wherein

the filament ends at the proximal and/or distal end of the braiding are each brought together at least in pairs and connected with each other permanently, and

with the filament ends connected with each other being shaped so as to be atraumatic, characterized in that

the filaments crossing one another at the points of intersection located distally from the proximal ends are connected with each other at said points of intersection in the area of the proximal end of the implant, in the following manner:

the intersected filaments in the area of the proximal end of the implant are passed through loops formed by wires secured at the proximal end of the implant, the wires originating from the points where the filaments are brought together at the proximal end of the implant, the starting point and the end point of the wires being at the proximal end of the implant, the individual wires extending from the proximal point of attachment in distal direction and passed around the proximal points of intersection of the filaments.

2. An implant according to claim 1, characterized in that the filaments crossing each other are connected with each other at points of intersection located farthest to the proximal end and distally to the filament ends.

3. An implant according to claim 1, characterized in that radiopaque markings are arranged at the ends of the filaments brought together at the proximal and/or distal end of the implant.

4. An implant according to claim 3, characterized in that the radiopaque markers are sleeves surrounding the joined filaments.

5. An implant according to claim 4, characterized in that the sleeves surrounding the joined filaments located adjacent to one another are of staggered arrangement with respect to each other in axial direction.

6. An implant according to claim 1, characterized in that the filaments are metallic individual wires or strands.

7. An implant according to claim 1, characterized in that connecting elements are arranged at the proximal and/or distal filament ends, with said connecting elements extending in proximal or distal direction and being provided with thickenings at their ends.

8. A combination comprising an implant according to claim 1 and a pusher wire, wherein the implant is attached to the pusher wire via a retaining element.

9. A combination according to claim 8, characterized in that thickenings are arranged at the proximal end of the implant which are held in a form-closed manner by the retaining element, wherein a portion of the retaining element is designed so as to be electrolytically corrodible so that the proximal end of the implant is set free when said portion has been dissolved electrolytically.

10. A combination according to claim 9, characterized in that the corrodibly designed portion of the retaining element is provided in the form of a disk with an opening, wherein the thickenings located at the proximal end of the implant extend through said opening and wherein the diameter of the opening is adapted to the thickenings in such a manner that said thickenings cannot pass through the opening as long as the disk is left intact.

11. A combination according to claim 8, characterized in that the pusher wire is provided with a pusher wire tip extending from the distal end of the pusher wire further in direction of the distal end of the implant and into the interior of the implant up to the distal end of the implant or even beyond it.