Dialysis system with flow regulation device

• US 10,265,454 B2
• Filed: 07/25/2008
• Issued: 04/23/2019
• Est. Priority Date: 07/25/2008
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Rohde, Justin B., Maliekkal, Shincy J.
• Primary Examiner(s): Bass, Dirk R
• Application Number:
  US12/180,324
• Publication Number:
  US 20100018923A1
• Time in Patent Office: 3,924 Days
• CPC Class Codes: A61M 1/1635 with volume chamber balancing devices between used and fresh dialysis fluid
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates

Abstract

A dialysis system includes a dialysis machine with a variable fluid demand including at least a lower demand and a higher demand. A fluid source is in fluid communication with the dialysis machine and provides fluid to the dialysis machine at a fluid flow rate. A flow regulation device includes a fluid inlet in fluid communication with the fluid source and a fluid outlet in fluid communication with the dialysis machine. The flow regulation device is operable to expand and contract to provide a variable internal volume. The flow regulation device expands when the dialysis machine has the lower demand and contracts when the dialysis machine has the higher demand.

Claims

1. A dialysis system comprising:

a dialysis machine with a variable fluid demand including at least a lower demand and a higher demand;

a purified water source in fluid communication with the dialysis machine and providing purified water to the dialysis machine at a fluid flow rate; and

a flow regulation device comprising a closed volume having a cross-sectional area larger than that of its purified water inlet and purified water outlet, the inlet in fluid communication with the purified water source, the outlet in fluid communication with the dialysis machine, the flow regulation device including a compliant material in sealed communication with the purified water inlet and the purified water outlet such that the purified water contacts the compliant material without passing through the compliant material, the compliant material operable to expand and contract to provide a variable internal volume, and wherein the compliant material of the flow regulation device expands when the dialysis machine has the lower demand and contracts when the dialysis machine has the higher demand.

2. The dialysis system of claim 1, wherein the dialysis machine produces dialysate from the purified water.

3. The dialysis system of claim 1 wherein the flow regulation device comprises a first wall and a second wall disposed opposite each other between the purified water inlet and the purified water outlet to define in part the internal volume, wherein the first wall and the second wall are composed of the compliant material.

4. The dialysis system of claim 3 wherein the first wall and the second wall move away from each other when the device expands and move towards each other when the device contracts.

5. The dialysis system of claim 1 wherein the flow regulation device comprises a pleated wall, the pleated wall expanding outwardly and contracting inwardly to provide the variable internal volume.

6. The dialysis system of claim 1 wherein the flow regulation device provides a maximum internal volume between 25 mL and 200 mL.

7. The dialysis system of claim 6 wherein the maximum internal volume of the flow regulation device is between 50 ml and 100 ml.

8. The dialysis system of claim 1 wherein the purified water source comprises a system for preparing the purified water from a water source.

9. The dialysis system of claim 1 wherein the fluid flow rate from the purified water source is generally constant.

10. The dialysis system of claim 9 wherein the fluid flow rate from the purified water source is generally equal to an average fluid demand of the dialysis machine.

11. The dialysis system of claim 1 wherein the dialysis machine is a hemodialysis machine.

12. A dialysis system comprising:

a dialysis machine with a variable fluid demand including at least a lower demand and a higher demand;

a fluid source in fluid communication with the dialysis machine and providing fluid to the dialysis machine at a fluid flow rate; and

a flow regulation device comprising a fluid inlet in fluid communication with the dialysis fluid source and a fluid outlet in fluid communication with the dialysis machine, wherein the flow regulation device contains a gas that contacts the fluid from the fluid source and provides a gas volume, and wherein the flow regulation device is configured to discharge gas from the flow regulation device and/or intake gas into the flow regulation device to regulate the gas volume to provide a variable fluid volume, the flow regulation device providing a maximum fluid volume between 25 mL and 200 mL, wherein the gas volume decreases when the dialysis machine has the lower demand and increases when the dialysis machine has the higher demand.

13. The dialysis system of claim 12 wherein the flow regulation device comprises a rigid canister.

14. The dialysis system of claim 12 wherein the gas volume is regulated by discharging gas from the flow regulation device and taking gas into the flow regulation device.

15. The dialysis system of claim 14 further comprising a filter for filtering gas entering the flow regulation device.

16. A dialysis system comprising:

a dialysis machine;

a dialysate production unit housed in the dialysis machine;

a purified water source in fluid communication with the dialysate production unit and providing fluid to the dialysis machine at a fluid flow rate;

a controller provided with the dialysis machine and configured to control a variable fluid demand of the dialysate production unit; and

a flow control mechanism including a closed volume having a cross-sectional diameter larger than its inlet and outlet diameters and including a compliant material, the flow control mechanism located between the purified water source and the dialysate production unit for storing purified water to help satisfy the variable fluid demand of the dialysate production unit.

17. The dialysis system of claim 16 wherein the flow control mechanism is actively controlled by the controller.

18. The dialysis system of claim 16 wherein the flow control mechanism includes a first wall and a second wall disposed opposite each other.

19. The dialysis system of claim 16, wherein the dialysate production unit includes at least one concentrate pump controlled by the controller, the concentrate pump affecting the variable demand of the dialysate production unit.

20. The dialysis system of claim 16, wherein the flow control mechanism includes a flexible portion that expands and contracts depending upon the fluid demand of the dialysate production unit, the flexible portion comprising the compliant material.

21. The dialysis system of claim 16, wherein the compliant material contacts purified water from the purified water source without passing through the compliant material.

22. A dialysis system comprising:

a dialysis machine with a variable fluid demand including at least a lower demand and a higher demand;

a purified water source in fluid communication with the dialysis machine and providing purified water to the dialysis machine at a fluid flow rate, the dialysis machine producing dialysate from the purified water; and

a flow regulation device including a closed volume having a cross-sectional area larger than that of its purified water inlet and purified water outlet, the inlet in fluid communication with the purified water source, the flow regulation device including a compliant material in sealed communication with the purified water inlet and the purified water outlet such that the purified water contacts the compliant material, the contacting of the purified water performed without passing through the compliant material, the compliant material operable to expand and contract to provide a variable internal water volume, and wherein the variable internal water volume increases when the dialysis machine has the lower demand and the variable internal water volume decreases when the dialysis machine has the higher demand.

23. The dialysis system of claim 22, wherein the flow regulation device comprises a first wall and a second wall disposed opposite each other between the purified water inlet and the purified water outlet to define in part the internal water volume, wherein the first wall and the second wall are composed of the compliant material.

24. The dialysis system of claim 23, wherein the first wall and the second wall move away from each other when the device expands and move towards each other when the device contracts.

25. The dialysis system of claim 22, wherein the flow regulation device comprises a pleated wall, the pleated wall expanding outwardly and contracting inwardly to provide the variable internal water volume.

26. The dialysis system of claim 22, wherein the flow regulation device provides a maximum internal volume between 25 mL and 200 mL.

27. The dialysis system of claim 22, wherein the purified water source includes a system for preparing the purified water from a water source.

28. The dialysis system of claim 22, wherein the fluid flow rate from the purified water source is generally constant.