Biological test strip with isolation structure

• US 10,267,791 B2
• Filed: 05/04/2017
• Issued: 04/23/2019
• Est. Priority Date: 05/05/2016
• Status: Active Grant

• Current Assignee: Vida BioTechnology Co., Ltd.
• Original Assignee: Vida BioTechnology Co., Ltd.
• Inventors: Wang, Wen-Chih, Gu, Bing-Chen, Dai, Yu-Han
• Primary Examiner(s): Chin, Christopher L
• Application Number:
  US15/586,728
• Publication Number:
  US 20170322205A1
• Time in Patent Office: 719 Days
• Field of Search: 204400, 20440301, 20440303, 204412, 422 8201
• CPC Class Codes: G01N 27/07 Construction of measuring vessels; Electrodes therefor
• CPC Class Codes: G01N 27/3276 being a hybridisation with immobilised receptors using a FET type sensor G01N27/4145; concerning the hybridisation C12Q1/68
• CPC Class Codes: G01N 33/5438 Electrodes

Abstract

A biological test strip with isolation structure includes a substrate having a testing portion and a measuring portion; an electrode disposed on the substrate and including an operation electrode and an auxiliary electrode, the operation electrode having a first operating end and a first reading end, the auxiliary electrode having a second operating end and a second reading end; a first flow confining member surrounding the first operating end; and a second flow confining member surrounding the first flow confining member and the second operating end, with a height of the second flow confining member larger than a height of the first flow confining member. Therefore, the flowing scope of the dropped liquid is confined, so as to fix the square measure of the dropped liquid contacting the electrode and thereby improve the analysis repeatability.

Claims

1. A biological test strip with isolation structure, comprising:

a substrate including a testing portion and a measuring portion;

an electrode disposed on the substrate and further including an operation electrode and an auxiliary electrode, the operation electrode provided with a first operating end disposed on the testing portion and a first reading end disposed on the measuring portion, the auxiliary electrode provided with a second operating end disposed on the testing portion and a second reading end disposed on the measuring portion;

a first flow confining member disposed on the measuring portion and surrounding the first operating end of the operation electrode; and

a second flow confining member disposed on the testing portion and further surrounding the first flow confining member and the second operating end of the auxiliary electrode, a height of the second flow confining member against the substrate is larger than a height of the first flow confining member against the substrate.

2. The biological test strip of claim 1, wherein the height of the first flow confining member ranges from 0.25 mm to 0.5 mm, and the height of the second flow confining member is larger than 0.8 mm.

3. The biological test strip of claim 1, wherein the first flow confining member and the second flow confining member are formed of an insulator material.

4. The biological test strip of claim 3, wherein the insulator material is silica gel.

5. The biological test strip of claim 1, wherein the electrode includes a reference electrode which is also surrounded by the second flow confining member, the reference electrode further including a third operating end disposed on the testing portion and a third reading end disposed on the measuring portion.