System and method for reconstructing cardiac activation information
First Claim
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1. A method of representing cardiac information associated with a heart rhythm disorder, the method comprising:
- accessing, using a computing device, a plurality of neighboring cardiac signals obtained from a patient;
eliminating, using the computing device, far-field activations from the plurality of neighboring cardiac signals by;
processing a first cardiac signal and a second cardiac signal of the plurality of neighboring cardiac signals to determine whether there is a point of change in the first cardiac signal at which a derivative of the first cardiac signal diverges with respect to a derivative of the second cardiac signal above a threshold; and
assigning an activation onset time in the first cardiac signal at the point of change to define a local activation if the point of change is in the first cardiac signal; and
constructing, using the computing device, a clinical representation of local activations in the plurality of neighboring cardiac signals.
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Abstract
Reconstruction of cardiac information associated with a heart rhythm disorder includes accessing a plurality of neighboring cardiac signals and eliminating far-field activations from the neighboring cardiac signals using one or more divergence criteria that define local activations, where the divergence criteria is associated with divergence among the plurality of neighboring cardiac signals. The local activations in the plurality of neighboring cardiac signals may be used to construct a clinical representation of the heart rhythm disorder.
233 Citations
25 Claims
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1. A method of representing cardiac information associated with a heart rhythm disorder, the method comprising:
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accessing, using a computing device, a plurality of neighboring cardiac signals obtained from a patient; eliminating, using the computing device, far-field activations from the plurality of neighboring cardiac signals by; processing a first cardiac signal and a second cardiac signal of the plurality of neighboring cardiac signals to determine whether there is a point of change in the first cardiac signal at which a derivative of the first cardiac signal diverges with respect to a derivative of the second cardiac signal above a threshold; and assigning an activation onset time in the first cardiac signal at the point of change to define a local activation if the point of change is in the first cardiac signal; and constructing, using the computing device, a clinical representation of local activations in the plurality of neighboring cardiac signals. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A system of representing cardiac information associated with a heart rhythm disorder, the system comprising a computing device configured to:
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access a plurality of neighboring cardiac signals obtained from a patient; eliminate far-field activations from the plurality of neighboring cardiac signals by processing a first cardiac signal and a second cardiac signal of the plurality of cardiac signals to determine whether there is a point of change in the first cardiac signal at which a derivative of the first cardiac signal diverges with respect to a derivative of the second cardiac signal above a threshold and assigning an activation onset time in the first cardiac signal at the point of change to define a local activation if the point of change is in the first cardiac signal; and construct a clinical representation of local activations in the plurality of neighboring cardiac signals. - View Dependent Claims (23, 24)
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25. A method of representing cardiac information associated with a heart rhythm disorder, the method comprising:
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accessing, using a computing device, a plurality of signal pairs of neighboring cardiac signals obtained from a patient, each signal pair having a first cardiac signal and a second cardiac signal; processing, using the computing device, each signal pair to eliminate far-field activations by determining whether there is a point of change in the first cardiac signal at which a derivative of the first cardiac signal diverges with respect to a derivative of the second cardiac signal above a threshold; assigning, using the computing device, an activation onset time in the first cardiac signal at the point of change to define a local activation if the point of change is in the first cardiac signal; repeating the processing and the assigning for additional signal pairs, each additional signal pair having a different second cardiac signal, to define multiple local activations in the first cardiac signal in each of the additional signal pairs; and constructing, using the computing device, a clinical representation based on the multiple local activations of the plurality of signal pairs to indicate a source of the heart rhythm disorder.
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Specification