Endovascular implant

• US 10,271,973 B2
• Filed: 03/14/2018
• Issued: 04/30/2019
• Est. Priority Date: 06/03/2011
• Status: Active Grant

• Current Assignee: Intact Vascular, Inc. (Koninklijke Philips N.V.)
• Original Assignee: Intact Vascular, Inc. (Koninklijke Philips N.V.)
• Inventors: Giasolli, Robert, Schneider, Peter
• Primary Examiner(s): Stransky, Katrina M
• Application Number:
  US15/921,477
• Publication Number:
  US 20180200087A1
• Time in Patent Office: 412 Days
• CPC Class Codes: A61F 2/844 folded prior to deployment
• CPC Class Codes: A61F 2/848 having means for fixation to the vessel wall, e.g. barbs
• CPC Class Codes: A61F 2/86 Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/92 Stents in the form of a rolled-up sheet expanding after insertion into the vessel , e.g. with a spiral shape in cross-section
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2002/825 having longitudinal struts
• CPC Class Codes: A61F 2002/826 more than one stent being applied sequentially
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2002/8486 provided on at least one of the ends
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2002/91583 by a bridge, whereby at least one of its ends is connected along the length of a strut between two consecutive apices within a band
• CPC Class Codes: A61F 2002/9665 with additional retaining means
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0066 : stapled
• CPC Class Codes: A61F 2230/0054 : V-shaped
• CPC Class Codes: A61F 2250/0067 : Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 2250/0098 : radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61L 31/16 : Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence

Abstract

A plaque tack can be used for holding plaque against blood vessel walls such as in treating atherosclerotic occlusive disease. The plaque tack can be formed as a thin, annular band for holding loose plaque under a spring or other expansion force against a blood vessel wall. Focal elevating elements and/or other features, such as anchors, can be used to exert a holding force on a plaque position while minimizing the amount of material surface area in contact with the plaque or blood vessel wall and reducing the potential of friction with the endoluminal surface. This approach offers clinicians the ability to perform a minimally invasive post-angioplasty treatment and produce a stent-like result without using a stent.

Claims

1. A system for delivering a vascular prosthesis, comprising:

an elongate body extending along a longitudinal axis between a proximal end and a distal end, the elongate body comprising;

a plurality of annular recesses disposed adjacent the distal end of the elongate body;

a plurality of proximal shoulders;

a plurality of distal shoulders, wherein each annular recess of the plurality of annular recesses is situated between one proximal shoulder of the plurality of proximal shoulders and one distal shoulder of the plurality of distal shoulders, wherein each shoulder of the pluralities of proximal and distal shoulders has a radially extending face perpendicular to the longitudinal axis; and

a plurality of cylindrical regions, wherein each cylindrical region of the plurality of cylindrical regions is formed by a proximal shoulder of the plurality of proximal shoulders at an adjacent first annular recess of the plurality of annular recesses and a distal shoulder of the plurality of distal shoulders at an adjacent second annular recess of the plurality of annular recesses, wherein each cylindrical region of the plurality of cylindrical regions has an outer diameter greater than an outer diameter of the adjacent first and second annular recesses of the plurality of annular recesses and comprises an annular radiopaque marker band;

a sheath having a proximal end and a distal end, the sheath being moveable relative to the elongate body from a first position in which the distal end of the sheath is disposed distally of a distal-most annular recess of the plurality of annular recesses to a second position in which the distal end of the sheath is disposed proximally of at least the distal-most annular recess of the plurality of annular recesses; and

a plurality of self-expanding intravascular tacks, each self-expanding intravascular tack of the plurality of self-expanding intravascular tacks having a series of radiopaque markers, each self-expanding intravascular tack of the plurality of self-expanding intravascular tacks comprising a proximal annular member, a distal annular member, and a plurality of bridge members forming a single column of cells, and each self-expanding intravascular tack of the plurality of self-expanding intravascular tacks being disposed about a corresponding annular recess of the plurality of annular recesses and between corresponding proximal and distal shoulders of the pluralities of proximal and distal shoulders, wherein each self-expanding intravascular tack of the plurality of self-expanding intravascular tacks is disposed about a corresponding annular recess of the plurality of annular recesses such that a distal end of a first self-expanding intravascular tack of the plurality of self-expanding intravascular tacks is spaced a distance from a proximal end of an adjacent-most self-expanding intravascular tack of the plurality of self-expanding intravascular tacks, the distance being greater than half of a length of a self-expanding intravascular tack of the plurality of self-expanding intravascular tacks.

2. The system for delivering a vascular prosthesis of claim 1, wherein the radially extending faces of the pluralities of proximal and distal shoulders are configured to prevent axial slippage of the self-expanding intravascular tacks along the elongate body.

3. The system for delivering a vascular prosthesis of claim 1, wherein the distance between the distal end of the first self-expanding intravascular tack of the plurality of self-expanding intravascular tacks and the proximal end of the adjacent-most self-expanding intravascular tack of the plurality of self-expanding intravascular tacks is greater than the length of the self-expanding intravascular tack of the plurality of self-expanding intravascular tacks.

4. The system for delivering a vascular prosthesis of claim 1, wherein the series of radiopaque markers is positioned along a midline of each self-expanding intravascular tack of the plurality of self-expanding intravascular tacks.

5. The system for delivering a vascular prosthesis of claim 1, wherein the sheath further comprises a radiopaque marker strip at the distal end of the sheath, wherein the radiopaque marker strip is configured to be aligned with the series of radiopaque markers of each self-expanding intravascular tack of the plurality of self-expanding intravascular tacks prior to delivery of each self-expanding intravascular tack of the plurality of self-expanding intravascular tacks.

6. A system for delivering a vascular prosthesis, comprising:

an elongate body comprising a proximal end, a distal end, and a plurality of delivery platforms disposed adjacent the distal end of the elongate body, wherein each delivery platform of the plurality of delivery platforms comprises a recess having a fixed axial length and extending radially inwardly between a proximal shoulder and a distal shoulder;

a sheath having a proximal end and a distal end, the sheath being moveable relative to the elongate body from a first position in which the distal end of the sheath is disposed distally of a distal-most delivery platform of the plurality of delivery platforms to a second position in which the distal end of the sheath is disposed proximally of at least the distal-most delivery platform of the plurality of delivery platforms; and

a plurality of self-expanding intravascular implants, wherein each self-expanding vascular prosthesis of the plurality of self-expanding vascular prostheses comprises at least one radiopaque marker, and wherein each self-expanding vascular prosthesis of the plurality of self-expanding vascular prostheses is disposed about a corresponding delivery platform;

wherein the system is configured to separately place at least two self-expanding vascular prostheses of the plurality of self-expanding vascular prostheses in a body lumen such that after placement each self-expanding vascular prosthesis of the at least two self-expanding vascular prostheses does not contact any other self-expanding vascular prosthesis of the at least two self-expanding intravascular implants, wherein the at least two self-expanding vascular prostheses of the plurality of self-expanding vascular prostheses are held such that a distance between a proximal end of a first self-expanding vascular prosthesis of the at least two self-expanding vascular prostheses and a distal end of a second self-expanding vascular prosthesis of the at least two self-expanding vascular prostheses is greater than a length of either of the at least two self-expanding vascular prostheses of the plurality of self-expanding intravascular implants.

7. The system for delivering a vascular prosthesis of claim 6, wherein the at least two self-expanding vascular prostheses of the plurality of self-expanding vascular prostheses are held such that a distance between a proximal end of a first self-expanding vascular prosthesis of the at least two self-expanding vascular prostheses and a distal end of a second self-expanding vascular prosthesis of the at least two self-expanding vascular prostheses is at least 5 mm.

8. The system for delivering a vascular prosthesis of claim 6, wherein the length of each self-expanding vascular prosthesis of the plurality of self-expanding vascular prostheses is 15 mm or less.

9. The system for delivering a vascular prosthesis of claim 6, wherein each self-expanding vascular prosthesis of the plurality of self-expanding vascular prostheses is disposed between corresponding proximal and distal shoulders with corresponding radially extending faces perpendicular to a longitudinal axis of the elongate body to prevent axial slippage of the self-expanding vascular prosthesis along the elongate body.

10. The system for delivering a vascular prosthesis of claim 6, wherein the series of radiopaque markers is positioned along a midline of the self-expanding intravascular implant.

11. The system for delivering a vascular prosthesis of claim 6, wherein each self-expanding vascular prosthesis of the plurality of self-expanding vascular prostheses comprises a proximal sinusoidal ring defining a proximal end of the self-expanding vascular prosthesis and a distal sinusoidal ring defining a distal end of the self-expanding intravascular implant.

12. A system for delivering a vascular prosthesis, comprising:

an elongate body comprising a proximal end, a distal end, and a plurality of fixed delivery platforms disposed adjacent the distal end, wherein each delivery platform of the plurality of fixed delivery platforms comprises a recess extending distally of a radial protrusion;

a sheath having a proximal end and a distal end, wherein the sheath is moveable relative to the elongate body from a first position in which the distal end of the sheath is disposed distally of a distal-most delivery platform of the plurality of fixed delivery platforms to a second position in which the distal end of the sheath is disposed proximally of at least one delivery platform of the plurality of fixed delivery platforms; and

a plurality of self-expanding intravascular tacks, wherein each self-expanding intravascular tack of the plurality of self-expanding intravascular is disposed about a corresponding delivery platform of the plurality of fixed delivery platforms;

wherein the system is configured to place at least two self-expanding intravascular tacks of the plurality of self-expanding intravascular tacks such that a gap is provided between the distal end of a proximal self-expanding intravascular tack of the at least two self-expanding intravascular tacks and a proximal end of a distal self-expanding intravascular tack of the at least two self-expanding intravascular tacks.

13. The system for delivering a vascular prosthesis of claim 12, wherein the plurality of self-expanding intravascular tacks comprises between 3 and 20 self-expanding intravascular tacks.

14. The system for delivering a vascular prosthesis of claim 12, further comprising an expandable member configured to dilate a tack after deployment of the tack.

15. The system for delivering a vascular prosthesis of claim 12, wherein the radial protrusion comprises a marker band.

16. The system for delivering a vascular prosthesis of claim 12, wherein each self-expanding intravascular tack of the plurality of self-expanding intravascular tacks comprises a series of radiopaque markers.

17. The system for delivering a vascular prosthesis of claim 16, wherein the series of radiopaque markers are positioned along a midline of each self-expanding intravascular tack of the plurality of self-expanding intravascular tacks.

18. The system for delivering a vascular prosthesis of claim 16, wherein the sheath further comprises a radiopaque marker strip located adjacent the distal end of the sheath, wherein the radiopaque marker strip is configured to be aligned with the series of radiopaque markers of each self-expanding intravascular tack of the plurality of self-expanding intravascular tacks prior to placement of each self-expanding intravascular tack of the plurality of self-expanding intravascular tacks.