Imaging cartridge, pipette, and method of use for direct sputum smear microscopy
First Claim
Patent Images
1. An assembly for preparing a specimen for determining the presence of at least one microorganism specie in the specimen, the assembly comprising:
- a pipette configured to acquire a specimen from a sample wherein the pipette comprises an inlet, a sampling chamber, and a shaft disposed therebetween; and
an imaging cartridge configured to couple to the pipette such that the specimen is bio-contained therein, wherein the imaging cartridge comprises;
a pipette dock configured to at least partially receive the shaft of the pipette therein;
an imaging chamber configured to be in fluid communication with the pipette; and
a magnet disposed within the imaging chamber for preparing the specimen for imaging, wherein the magnet is configured to spread at least a portion of the specimen within the imaging chamber.
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Abstract
An assembly for preparing a specimen is provided that may be configured to determine the presence of at least one microorganism specie in the specimen. The assembly may include a pipette configured to acquire a specimen from a sample and an imaging cartridge configured to be in fluid communication with the pipette. The imaging cartridge and the pipette may be configured to be irreversibly coupled such that the specimen is bio-contained within the imaging cartridge and the pipette when the imaging cartridge and pipette are coupled together. Associated methods of use are also provided.
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Citations
18 Claims
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1. An assembly for preparing a specimen for determining the presence of at least one microorganism specie in the specimen, the assembly comprising:
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a pipette configured to acquire a specimen from a sample wherein the pipette comprises an inlet, a sampling chamber, and a shaft disposed therebetween; and an imaging cartridge configured to couple to the pipette such that the specimen is bio-contained therein, wherein the imaging cartridge comprises; a pipette dock configured to at least partially receive the shaft of the pipette therein; an imaging chamber configured to be in fluid communication with the pipette; and a magnet disposed within the imaging chamber for preparing the specimen for imaging, wherein the magnet is configured to spread at least a portion of the specimen within the imaging chamber. - View Dependent Claims (2, 3, 4, 5, 6)
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7. An imaging cartridge for preparing a specimen for determining an amount of at least one microorganism specie, the imaging cartridge comprising:
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a pipette dock configured to couple to a pipette containing a specimen such that the specimen is bio-contained therein; at least one reagent for preparing the specimen for imaging; an imaging chamber configured to be in fluid communication with the pipette; and a magnet disposed within the imaging chamber for preparing the specimen for imaging, wherein the magnet is configured to spread at least a portion of the specimen within the imaging chamber. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. An imaging cartridge for preparing a specimen for determining an amount of at least one microorganism specie, the imaging cartridge comprising:
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a pipette dock configured to couple to a pipette containing a specimen such that the specimen is bio-contained therein; at least one reagent for preparing the specimen for imaging; an imaging chamber configured to be in fluid communication with the pipette, wherein the prepared specimen is configured to be spread in the imaging chamber for obtaining an image thereof; and a magnet disposed within the imaging chamber, the magnet configured to move from one end of the imaging chamber to an opposite end of the imaging chamber for spreading the specimen therein.
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Specification