Implantable scaffolds and methods for treatment of sinusitis
First Claim
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1. A scaffold configured for implantation into a human sinus comprising:
- (a) a tubular scaffold comprising a plurality of braided polymeric strands that comprise a first biodegradable polymer material and(b) a conformal coating over the tubular scaffold that comprises a crosslinked biodegradable elastomer material, wherein the biodegradable elastomer material is formed by reacting a branched poly(lactide-co-caprolactone) polyol with a diisocyanate crosslinking agent; and
wherein the scaffold is adapted to conform to the shape of the sinus cavity.
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Abstract
This disclosure describes, inter alia, materials, devices, kits and methods for the treatment of chronic sinusitis. Disclosed are medical scaffolds configured for placement within a sinus of a patient, methods of making the implants and methods of treatment. The scaffolds comprise a woven or non-woven structure having a substantially tubular configuration, a conformal coating over the tubular scaffold and optionally, a drug coating.
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24 Claims
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1. A scaffold configured for implantation into a human sinus comprising:
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(a) a tubular scaffold comprising a plurality of braided polymeric strands that comprise a first biodegradable polymer material and (b) a conformal coating over the tubular scaffold that comprises a crosslinked biodegradable elastomer material, wherein the biodegradable elastomer material is formed by reacting a branched poly(lactide-co-caprolactone) polyol with a diisocyanate crosslinking agent; and wherein the scaffold is adapted to conform to the shape of the sinus cavity. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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Specification