Endovascular impant

• US 10,278,839 B2
• Filed: 06/01/2016
• Issued: 05/07/2019
• Est. Priority Date: 12/12/2007
• Status: Active Grant

• Current Assignee: Intact Vascular, Inc. (Koninklijke Philips N.V.)
• Original Assignee: Intact Vascular, Inc. (Koninklijke Philips N.V.)
• Inventors: Giasolli, Robert, Schneider, Peter
• Primary Examiner(s): Stransky, Katrina M
• Application Number:
  US15/170,772
• Publication Number:
  US 20170000629A1
• Time in Patent Office: 1,070 Days
• CPC Class Codes: A61F 2/844 folded prior to deployment
• CPC Class Codes: A61F 2/848 having means for fixation to the vessel wall, e.g. barbs
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2002/825 having longitudinal struts
• CPC Class Codes: A61F 2002/826 more than one stent being applied sequentially
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2002/8486 provided on at least one of the ends
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2002/91583 by a bridge, whereby at least one of its ends is connected along the length of a strut between two consecutive apices within a band
• CPC Class Codes: A61F 2002/9665 with additional retaining means
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0066 stapled

Abstract

A plaque tack can be used for holding plaque against blood vessel walls such as in treating atherosclerotic occlusive disease. The plaque tack can be formed as a thin, annular band for holding loose plaque under a spring or other expansion force against a blood vessel wall. Focal elevating elements and/or other features, such as anchors, can be used to exert a holding force on a plaque position while minimizing the amount of material surface area in contact with the plaque or blood vessel wall and reducing the potential of friction with the endoluminal surface. This approach offers clinicians the ability to perform a minimally invasive post-angioplasty treatment and produce a stent-like result without using a stent.

Claims

1. A self-expanding intravascular implant comprising:

a proximal undulating ring on a proximal side of the intravascular implant comprising a plurality of proximal struts, the plurality of proximal struts comprising a plurality of first proximal struts and a plurality of second proximal struts, wherein each first proximal strut of the plurality of first proximal struts is connected to at least one second proximal strut of the plurality of second proximal struts, wherein a proximal end of each first proximal strut of the plurality of first proximal struts is connected to a proximal end of a second proximal strut of the plurality of second proximal struts to form a plurality of first proximal apices and a distal end of each first proximal strut of the plurality of first proximal struts is connected to a distal end of a second proximal strut of the plurality of second proximal struts to form a plurality of first distal apices, wherein at least one first proximal apex of the plurality of first proximal apices defines a proximal end of the intravascular implant;

a distal undulating ring on a distal side of the intravascular implant comprising a plurality of distal struts, the plurality of distal struts comprising a plurality of first distal struts and a plurality of second distal struts, wherein each first distal strut of the plurality of first distal struts is connected to at least one second distal strut of the plurality of second distal struts, wherein a distal end of each first distal strut of the plurality of first distal struts is connected to a distal end of a second distal strut of the plurality of second distal struts to form a plurality of second distal apices and a proximal end of each first distal strut of the plurality of first distal struts is connected to a proximal end of a second distal strut of the plurality of second distal struts to form a plurality of second proximal apices, wherein at least one second distal apex of the plurality of second distal apices defines a distal end of the intravascular implant;

at least one bridge member located between the proximal undulating ring and the distal undulating ring and connecting at least one first distal apex of the plurality of first distal apices to at least one second proximal apex of the plurality of second proximal apices;

wherein the intravascular implant has a compression force curve being a measure of the amount of radial compression force required to compress the intravascular implant along a range of outer diameters, and has an expansion force curve being a measure of the amount of radial expansion force exerted by the intravascular implant when the intravascular implant self-expands along the range of outer diameters, wherein the range of outer diameters is at least about 2 mm and a change in radial force along the expansion force curve is no more than about 3 Newtons (N) along the range of outer diameters.

2. The self-expanding intravascular implant of claim 1, wherein the range of outer diameters is at least about 3 mm.

3. The self-expanding intravascular implant of claim 2, wherein the range of outer diameters is at least about 5 mm.

4. The self-expanding intravascular implant of claim 1, wherein the range of outer diameters is from about 3 mm to at least about 6 mm.

5. The self-expanding intravascular implant of claim 1, wherein a maximum radial expansion force on the expansion force curve is no more than about 5 N.

6. The self-expanding intravascular implant of claim 5, wherein the maximum radial expansion force on the expansion force curve is no more than about 3 N.

7. The self-expanding intravascular implant of claim 6, wherein the maximum radial expansion force on the expansion force curve is no more than about 1 N.

8. The self-expanding intravascular implant of claim 1, wherein the change in the radial expansion force between any two points on the expansion force curve is no more than about 2 N.

9. The self-expanding intravascular implant of claim 8, wherein the change in the radial expansion force between any two points on the expansion force curve is no more than about 1 N.

10. The self-expanding intravascular implant of claim 1, wherein the range of outer diameters is from about 3 mm to at least about 6 mm and a radial expansion force of the self-expanding intravascular implant is no more than about 2 N through the range of outer diameters.

11. The self-expanding intravascular implant of claim 1, wherein a radial expansion force is no more than about 2 N at an outer diameter of about 3 mm and drops to no more than about 1 N at an outer diameter of about 6 mm.

12. The self-expanding intravascular implant of claim 1, wherein the difference between the expansion force curve and the compression force curve at any outer diameter along the range of outer diameters is no more than about 3 N.

13. The self-expanding intravascular implant of claim 12, wherein the difference between the expansion force curve and the compression force curve at any outer diameter along the range of outer diameters is no more than about 2 N.

14. The self-expanding intravascular implant of claim 13, wherein the difference between the expansion force curve and the compression force curve at any outer diameter along the range of outer diameters is no more than about 1 N.

15. A self-expanding intravascular implant comprising:

a single proximal undulating ring having a dual amplitude and defining a proximal end of the self-expanding intravascular implant;

a single distal undulating ring having a dual amplitude and defining a distal end of the self-expanding intravascular implant; and

a plurality of bridge members directly connecting the single proximal undulating ring and the single distal undulating ring thereby forming a single column of cells;

wherein the self-expanding intravascular implant is radially self-expandable through a range of diameters of at least about 2 mm and has a change in radial expansion force no more than about 3 Newtons (N) through the range of diameters.

16. The self-expanding intravascular implant of claim 15, wherein the range of outer diameters is at least about 3 mm.

17. The self-expanding intravascular implant of claim 16, wherein the range of outer diameters is at least about 5 mm.

18. The self-expanding intravascular implant of claim 15, wherein the change in the radial expansion force between any two points on the expansion force curve is no more than about 2 N.

19. The self-expanding intravascular implant of claim 18, wherein the change in the radial expansion force between any two points on the expansion force curve is no more than about 1 N.

20. A self-expanding intravascular implant comprising:

a tubular body having a proximal end, a distal end and a lumen extending therethrough, the tubular body comprising a zig-zag distal-most ring and a zig-zag proximal-most ring connected to each other by a plurality of bridge members, the tubular body forming only a single column of cells which comprises at least one open cell bound by the zig-zag distal-most ring, a first bridge member of the plurality of bridge members the zig-zag proximal-most ring, and a second bridge member of the plurality of bridge members, wherein the tubular body has a compression force curve being a measure of the amount of radial compression force required to compress the tubular body along a range of outer diameters, and has an expansion force curve being a measure of the amount of radial expansion force exerted by the tubular body when the tubular body self-expands through the range of outer diameters which range of outer diameters at least about 2 mm, the compression force is greater than the expansion force through the range of outer diameters, and a difference between the radial force of the compression force curve and the expansion force curve is no more than about 3 Newtons (N) through the range of outer diameters.

21. The self-expanding intravascular implant of claim 20, wherein the range of outer diameters is at least about 3 mm.

22. The self-expanding intravascular implant of claim 21, wherein the range of outer diameters is at least about 5 mm.

23. The self-expanding intravascular implant of claim 20, wherein the difference between the radial force of the compression force curve and the expansion force curve is no more than about 2 N through the range of outer diameters.

24. The self-expanding intravascular implant of claim 23, wherein the difference between the radial force of the compression force curve and the expansion force curve is no more than about 1 N through the range of outer diameters.