Head modeling for a therapeutic or diagnostic procedure

• US 10,282,515 B2
• Filed: 09/08/2017
• Issued: 05/07/2019
• Est. Priority Date: 02/10/2014
• Status: Active Grant

• Current Assignee: Neuronetics, Inc.
• Original Assignee: Neuronetics, Inc.
• Inventors: Mainkar, Neeraj, Pillutla, Ravi, Ghiron, Kenneth Marc, Riehl, Mark Edward
• Primary Examiner(s): Zalalee, Sultana M
• Application Number:
  US15/699,392
• Publication Number:
  US 20170372006A1
• Time in Patent Office: 606 Days
• CPC Class Codes: G06F 18/00 Pattern recognition
• CPC Class Codes: G06T 17/00 Three dimensional [3D] modelling, e.g. data description of 3D objects
• CPC Class Codes: G06T 2210/44 Morphing
• CPC Class Codes: G06V 40/16 Human faces, e.g. facial parts, sketches or expressions
• CPC Class Codes: G16H 20/40 relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
• CPC Class Codes: G16H 30/20 for handling medical images, e.g. DICOM, HL7 or PACS
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/50 for simulation or modelling of medical disorders

Abstract

A model of a human subject'"'"'s head may be generated to assist in a therapeutic and/or diagnostic procedure. A treatment and/or diagnostic system may generate a fitted head model using a predetermined head model and a plurality of points. The plurality of points may include facial feature information and may be determined using a sensor, for example, an IR or optical sensor. One or more anatomical landmarks may be determined and registered in association with the fitted head model using the facial feature information, for example, without the use of additional image information, such as an MRI image. The fitted head model may include visual aids, for example, anatomical landmarks, reference points, marking of the human subject'"'"'s MT location, and/or marking of the human subject'"'"'s treatment location. The visual aids may assist a technician to perform the therapeutic and/or diagnostic procedure of the human subject.

Claims

1. A system for creating a digital three-dimensional reconstruction of a human subject'"'"'s head, the system comprising:

a treatment coil;

a sensor; and

a processor configured to;

determine a plurality of points associated with the human subject'"'"'s head using the sensor and without requiring the use of magnetic resonance imaging (MRI) image information, x-ray image information, or computer tomography (CT) image information, wherein the plurality of points are devoid of information relating to the human subject'"'"'s hair, and wherein a subset of the plurality of points comprise facial feature information;

generate a fitted head model using a predetermined head model and the plurality of points such that the fitted head model is devoid of information relating to the human subject'"'"'s hair;

determine a location of one or more anatomical landmarks on the fitted head model using the facial feature information, the anatomical landmarks comprising one or more of a nasion, an inion, a lateral canthus, an external auditory meatus, or one or more preauricular points of the human subject;

determine a position of the treatment coil based on the one or more anatomical landmarks and without requiring the use of magnetic resonance imaging (MRI) image information, x-ray image information, or computer tomography (CT) image information; and

perform transcranial magnetic stimulation (TMS) at a treatment location using the treatment coil.

2. The system of claim 1, wherein the treatment location corresponds to an anatomical region within a human brain and is associated with a neuropsychiatric disorder.

3. The system of claim 1, wherein the sensor comprises an image sensor.

4. The system of claim 1, wherein the processor is configured to determine the plurality of points using the sensor and without the use of an indicator tool.

5. The system of claim 1, wherein one or more of the predetermined head model or the fitted head model comprises an electroencephalogram 10-20 coordinate grid.

6. The system of claim 1, wherein the fitted head model has a smooth surface.

7. The system of claim 1, wherein the processor is further configured to:

determine that one or more points of the plurality of points are associated with rippling of the human subject'"'"'s skin, loss of a facial feature, or asymmetric lump; and

generate the fitted head model without the use of the one or more points associated with the rippling of the human subject'"'"'s skin, loss of a facial feature, or asymmetric lump.

8. The system of claim 1, further comprising a display device, wherein the processor is further configured to display the fitted head model and the treatment location or a reference point that is used to determine the treatment location on the display device.

9. The system of claim 1, wherein the processor is further configured to:

determine a second treatment location or a reference point that is used to determine the second treatment location on the fitted head model based on the one or more anatomical landmarks and without the use of additional image information; and

perform TMS at the second treatment location using the fitted head model.

10. The system of claim 1, wherein the processor is further configured to:

monitor a position of a TMS coil using the sensor while performing TMS;

determine that the position of the TMS coil falls outside of a predefined range with respect to the human subject'"'"'s head; and

alter or stop performing TMS.

11. The system of claim 1, wherein the processor is further configured to:

monitor a temperature of a TMS coil using the sensor while performing TMS;

determine that the temperature of the TMS coil falls outside of a temperature range; and

alter or stop performing TMS.

12. The system of claim 1, further comprising:

augmented reality (AR) goggles that comprise the sensor.

13. A method for creating a digital three-dimensional reconstruction of a human subject'"'"'s head, the method comprising:

determining a plurality of points associated with the human subject'"'"'s head using a sensor and without requiring the use of magnetic resonance imaging (MRI) image information, x-ray image information, or computer tomography (CT) image information, wherein a subset of the plurality of points comprise facial feature information;

determining that one or more points of the plurality of points are associated with the human subject'"'"'s hair;

generating a fitted head model using a predetermined head model and a subset of the plurality of points that are not associated with the human subject'"'"'s hair;

determining a location of one or more anatomical landmarks on the fitted head model using the facial feature information, the anatomical landmarks comprising one or more of a nasion, an inion, a lateral canthus, an external auditory meatus, or one or more preauricular points of the human subject;

determining a treatment location or a reference point that is used to determine the treatment location on the fitted head model based on the one or more anatomical landmarks and without requiring the use of magnetic resonance imaging (MRI) image information, x-ray image information, or computer tomography (CT) image information; and

performing transcranial magnetic stimulation (TMS) at the treatment location using the fitted head model.

14. The method of claim 13, wherein the treatment location corresponds to an anatomical region within a human brain and is associated with a neuropsychiatric disorder.

15. The method of claim 13, wherein the sensor comprises an image sensor.

16. The method of claim 13, wherein one or more of the predetermined head model or the fitted head model comprises an electroencephalogram 10-20 coordinate grid.

17. The method of claim 13, further comprising displaying the fitted head model and the treatment location or the reference point that is used to determine the treatment location on a display device to assist in performing TMS.

18. The method of claim 13, further comprising:

monitoring, while performing TMS, a position of a TMS coil using the sensor;

determining that the TMS coil falls outside of a predefined range with respect to the human subject'"'"'s head; and

altering or stopping the performance of TMS.

19. The method of claim 13, further comprising:

monitoring, while performing TMS, a temperature of a TMS coil using the sensor;

determining that the temperature of the TMS coil falls outside of a predefined range; and

altering or stopping the performance of TMS.

20. A method for creating a digital three-dimensional reconstruction of a human subject'"'"'s head, the method comprising:

determining a plurality of points associated with the human subject'"'"'s head using a sensor by moving a transcranial magnetic stimulation (TMS) coil around the human subject'"'"'s head such that the plurality of points are devoid of information relating to the human subject'"'"'s hair, wherein a subset of the plurality of points comprise facial feature information, and wherein the sensor is configured to determine the location of the TMS coil;

generating a fitted head model using a predetermined head model and the plurality of points, such that the fitted head model is devoid of information relating to the human subject'"'"'s hair;

determining a location of one or more anatomical landmarks on the fitted head model using the facial feature information, the anatomical landmarks comprising one or more of a nasion, an inion, a lateral canthus, an external auditory meatus, or one or more preauricular points of the human subject;

determining a treatment location or a reference point that is used to determine the treatment location on the fitted head model based on the one or more anatomical landmarks and without requiring the use of magnetic resonance imaging (MRI) image information, x-ray image information, or computer tomography (CT) image information; and

performing TMS at the treatment location using the fitted head model.