Heart monitoring device and method

• US 10,285,650 B2
• Filed: 01/20/2015
• Issued: 05/14/2019
• Est. Priority Date: 01/20/2014
• Status: Active Grant

• Current Assignee: Imperial College of Science Technology & Medicine (Imperial College London)
• Original Assignee: Imperial Innovations Limited (Imperial College London)
• Inventors: Faisal, Aldo, Gavriel, Constantinos
• Primary Examiner(s): Stice, Paula J
• Application Number:
  US15/112,717
• Publication Number:
  US 20160338648A1
• Time in Patent Office: 1,575 Days
• CPC Class Codes: A61B 2503/40 Animals
• CPC Class Codes: A61B 2562/0219 Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
• CPC Class Codes: A61B 5/02438 with portable devices, e.g. worn by the patient
• CPC Class Codes: A61B 5/1102 Ballistocardiography
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/332 Portable devices specially adapted therefor
• CPC Class Codes: A61B 5/6823 Trunk, e.g., chest, back, abdomen, hip
• CPC Class Codes: A61B 5/6898 Portable consumer electronic devices, e.g. music players, telephones, tablet computers
• CPC Class Codes: A61B 5/7207 of noise induced by motion artifacts
• CPC Class Codes: A61B 5/725 using specific filters therefor, e.g. Kalman or adaptive filters A61B5/316 take precedence
• CPC Class Codes: A61B 5/7282 Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence

Abstract

A mobile telecommunications device arranged for monitoring the heart of a human or an animal includes at least one sensor for measuring an effect of heart function and producing a signal indicative of the effect, and a processor arranged to receive the signal and analyze it and to produce an output indicating a condition of the heart. A method of diagnosis of heart disease includes measuring an effect of heart function using one or more sensors, producing a signal indicative of the effect, and using a processor to receive the signal and analyze it and to produce an output indicating a condition of the heart.

Claims

1. A mobile telecommunications device placeable on a chest of a patient arranged for monitoring a heart of the patient, the patient being a human or an animal, the device comprising:

three motion sensors, each of the motion sensors measuring an effect of a function of the heart and producing a respective motion signal indicative of the effect; and

a processor adapted and arranged to receive and analyze the motion signals to produce a further motion signal which is independent of an orientation of the device with respect to the chest of the patient, wherein the further motion signal comprises a ballistocardiographic heart signal.

2. The device according to claim 1, wherein the processor is arranged to analyze the motion signals using principle component analysis to produce the further motion signal.

3. The device according to claim 1, wherein at least one of the motion signals includes a breathing component due to a breathing of the patient, the processor being arranged to remove the breathing component from the at least one of the motion signals.

4. The device according to claim 3, wherein the processor is arranged to remove the breathing component using a Savitzky-Golay smoothing algorithm.

5. The device according to claim 1, wherein the processor is arranged to identify heart beats of the heart in the further motion signal.

6. The device according to claim 5, wherein the further motion signal contains maxima and the processor is arranged to identify each of the maxima as representative of one of the heart beats.

7. The device according to claim 6, wherein the maxima are quasi-periodic.

8. The device according to claim 6, wherein the processor is arranged to define a time window of the further motion signal and to scan the time window to identify the maxima in the window.

9. The device according to claim 8, wherein the processor is arranged to identify one of the maxima by defining a cut-off value of the further motion signal and identify a first-occurring peak in the further motion signal above the cut-off value within the time window.

10. The device according to claim 9, wherein the cut-off value is calculated from at least one of:

a mean of the further motion signal, a median of the further motion signal, a standard deviation of the further motion signal, and an interquartile range of the further motion signal, within a predetermined period.

11. The device according to claim 9, wherein when a peak has been identified the processor is arranged to shift the time window to a time interval after the identified peak and to identify a next peak in the shifted time window.

12. The device according to claim 11, wherein the shifted time window is arranged to start a predetermined time after the peak.

13. A computer readable medium including instructions which when operated on a smartphone are arranged to cause the smartphone to operate as a device according to claim 1.

14. A method of testing, comprising the steps of:

contemporaneously recording an electrocardiographic (ECG) heart signal of a human or animal and a ballistocardiographic (BCG) signal of the human or animal using the device according to claim 1; and

comparing the ECG and BCG signals.

15. A method of diagnosis of heart disease in a heart of a patient, comprising the steps of:

placing a mobile telecommunications device on a chest of the patient, the mobile telecommunications device comprising three motion sensors;

measuring an effect of a function of the heart using each of the three motion sensors to generate three respective motion signals;

and analyzing the three motion signals to produce a further motion signal which is independent of an orientation of the device with respect to the chest of the patient, wherein the further motion signal comprises a ballistocardiographic heart signal.