Enhanced efficacy lung volume reduction devices, methods, and systems
First Claim
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1. A method for treating a lung of a patient, the lung including an airway system comprising a first airway and a second airway, the method comprising:
- evaluating a pretreatment localized density of the lung and/or a pretreatment density distribution map of the lung prior to applying a treatment procedure to the lung of the patient;
compressing a first portion of the lung during the treatment procedure with a first implantable coil deployed within the first airway so as to generate an increased tension in an uncompressed portion of the lung while permitting airflow in opposing directions past the first implantable coil, the first implantable coil having a distal end, a proximal end, and an elongate body extending between the distal end and the proximal end;
the first implantable coil being deployed from a constrained delivery configuration to an unconstrained delivery configuration so that the first portion of the lung is laterally compressed between the proximal end and the distal end in the unconstrained delivery configuration;
subsequent to the compression of the first portion of the lung with the first implantable coil, evaluating, using an imaging device, a resulting localized density of the lung and/or a resulting density distribution map of the lung to measure an effectiveness of the treatment procedure; and
if the measured effectiveness of the treatment procedure is less than an improvement threshold for the treatment procedure, continuing the treatment procedure by compressing a second portion of the lung with a second implantable coil deployed within the second airway of the lung.
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Abstract
A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.
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Citations
21 Claims
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1. A method for treating a lung of a patient, the lung including an airway system comprising a first airway and a second airway, the method comprising:
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evaluating a pretreatment localized density of the lung and/or a pretreatment density distribution map of the lung prior to applying a treatment procedure to the lung of the patient; compressing a first portion of the lung during the treatment procedure with a first implantable coil deployed within the first airway so as to generate an increased tension in an uncompressed portion of the lung while permitting airflow in opposing directions past the first implantable coil, the first implantable coil having a distal end, a proximal end, and an elongate body extending between the distal end and the proximal end;
the first implantable coil being deployed from a constrained delivery configuration to an unconstrained delivery configuration so that the first portion of the lung is laterally compressed between the proximal end and the distal end in the unconstrained delivery configuration;subsequent to the compression of the first portion of the lung with the first implantable coil, evaluating, using an imaging device, a resulting localized density of the lung and/or a resulting density distribution map of the lung to measure an effectiveness of the treatment procedure; and if the measured effectiveness of the treatment procedure is less than an improvement threshold for the treatment procedure, continuing the treatment procedure by compressing a second portion of the lung with a second implantable coil deployed within the second airway of the lung. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method for treating a lung of a patient, the lung including an airway system comprising a first airway and a second airway, the method comprising:
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evaluating a pretreatment residual volume of the lung of the patient prior to applying a treatment procedure to the lung of the patient; deploying a first coil within the first airway so as to compress a first portion of the lung to generate an increased tension in an uncompressed portion of the lung while permitting airflow in opposing directions past the first coil, the first coil having a distal end, a proximal end, and an elongate body extending between the distal end and the proximal end;
the first coil being deployed from a constrained delivery configuration to an unconstrained delivery configuration so that the first portion of the lung is laterally compressed between the proximal end and the distal end in the unconstrained delivery configuration;subsequent to the deployment of the first coil within the first airway, evaluating, using an imaging device, a resulting residual volume of the lung; and continuing treatment of the lung of the patient at the second airway of the lung if the resulting residual volume after compression of the first portion of the lung is less than 6% from the residual volume evaluated prior to the treatment of the lung of the patient by compressing a second portion of the lung from within the second airway with a second coil so as to generate an increased tension in the uncompressed portion of the lung.
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19. A method for treating a lung of a patient, the lung including an airway system comprising a first airway and a second airway, the method comprising:
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compressing a first portion of the lung during a treatment procedure by deploying a first implantable coil within the first airway so as to generate an increased tension in an uncompressed portion of the lung while permitting airflow through the first airway in opposing directions past the first implantable coil, the first implantable coil having a distal end, a proximal end, and an elongate body extending between the distal end and the proximal end;
the first implantable coil being deployed from a constrained delivery configuration to an unconstrained delivery configuration so that the first portion of the lung is laterally compressed between the proximal end and the distal end in the unconstrained delivery configuration;measuring, using an imaging device, a localized density of the lung and/or a density distribution of the lung during the compression of the first portion of the lung to measure a change in the localized density of the lung and/or a density distribution of the lung during the compression of the first portion of the lung; evaluating the measured change in the localized density of the lung and/or a density distribution of the lung during the compression of the first portion of the lung to determine an effectiveness of the treatment procedure; and if the determined effectiveness of the treatment procedure is less than an improvement threshold for the treatment procedure, continuing the treatment procedure by compressing a second portion of the lung with a second implantable coil deployed within the second airway of the lung. - View Dependent Claims (20, 21)
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Specification