Systems and methods for supporting or occluding a physiological opening or cavity

• US 10,285,709 B2
• Filed: 05/20/2016
• Issued: 05/14/2019
• Est. Priority Date: 09/05/2008
• Status: Active Grant

• Current Assignee: Pulsar Vascular, Inc. (Johnson & Johnson)
• Original Assignee: Pulsar Vascular, Inc. (Johnson & Johnson)
• Inventors: Gerberding, Brent, Abrams, Robert M., Clarke, Gilbert
• Primary Examiner(s): Orkin, Alexander J
• Application Number:
  US15/161,032
• Publication Number:
  US 20160262765A1
• Time in Patent Office: 1,089 Days
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12036 partial occlusion
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00778 Operations on blood vessels A61B2017/22097, A61B2017/320741 take precedence
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2017/00898 expandable upon contact with fluid
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/86 Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2240/001 Designing or manufacturing processes

Abstract

Implantable devices for placement at a cavity or opening such as an aneurysm are disclosed. The implantable devices, in a deployed condition, have a generally inverted U-shaped profile with a curved or angled framework support structure sized and configured for placement in proximity to tissue surrounding the opening and anchoring legs extending proximally from the framework structure sized and configured to contact the wall of a neighboring lumen at opposed locations. Occlusive and semi-occlusive membranes may be associated with the framework support structure and deployed over the opening to provide exclusion of the opening and flow diversion. Proximal anchoring segments providing additional lumen wall surface area contact for the implantable device following deployment may be incorporated.

Claims

1. An implantable device for treating a blood vessel having a physiological cavity, the implantable device comprising:

a body frame having a flow diverting section at a distal end and an anchoring section at a proximal end, a longitudinal axis extending from the distal end to the proximal end of the body frame, a first orthogonal axis substantially perpendicular to the longitudinal axis, and a second orthogonal axis substantially perpendicular to the longitudinal axis and the first orthogonal axis;

the flow diverting section of the body frame comprising a first pair of free ends, each of the first pair of free ends being longitudinally aligned along the first orthogonal axis and forming the distal end of the body frame allowing for positioning adjacent to or within the physiological cavity,

a first pair of anchoring segments and a second pair of anchoring segments being longitudinally aligned along the second orthogonal axis;

where the flow diverting section is folded about the first orthogonal axis such that the first pair of anchoring segments and the second pair of anchoring segments extend proximally from the flow diverting section on either side of the first pair of free ends to form the anchoring section and when deployed the first pair of anchoring segments expands away from the second pair of anchoring segments along the second orthogonal axis to anchor within a stem blood vessel at a blood vessel bifurcation, the stem blood vessel extending opposite the physiological cavity; and

a semi-occlusive flow diverting surface extending within a portion of the body frame between the first pair of free ends such the flow diverting surface partially occludes the physiological cavity while allowing flow along the first orthogonal axis adjacent to the flow diverting surface.

2. The implantable device of claim 1, where the body frame self-expands from a delivery condition to a deployed condition, a profile of the deployed condition being larger than a profile of the delivery condition.

3. The implantable device of claim 1, where the semi-occlusive flow diverting surface forms a curved surface when the flow diverting section is folded about the first orthogonal axis.

4. The implantable device of claim 1, further comprising at least one anchoring element extending proximally from at least one of the first pair of anchoring segments and the second pair of anchoring segments.

5. An implantable device for diverting blood flow from a physiological cavity, the implantable device comprising:

a body frame having a blocking section at a distal end and an anchoring section at a proximal end, a longitudinal axis extending from the distal end to the proximal end of the body frame, a first orthogonal axis substantially perpendicular to the longitudinal axis, and a second orthogonal axis substantially perpendicular to the longitudinal axis and the first orthogonal axis;

the blocking section of the body frame comprising a first pair of free ends, each end of the first pair of free ends being longitudinally aligned along the first orthogonal axis and forming the distal end of the body frame allowing for positioning adjacent to or within the physiological cavity such that the first orthogonal axis runs parallel to a side branch vessel at a vessel bifurcation;

a first pair of anchoring segments and a second pair of anchoring segments being longitudinally aligned along the second orthogonal axis;

where the blocking section is folded about the first orthogonal axis such that the first pair of anchoring segments and the second pair of anchoring segments extends proximally from the blocking section on either side of the first pair of free ends to form the anchoring section and when deployed the first pair of anchoring segments expands away from the second pair of anchoring segments along the second orthogonal axis to anchor within a stem vessel, the stem vessel feeding the side branch vessel at the bifurcation; and

a semi-occlusive blocking surface extending within a portion of the body frame between the first pair of free ends such that the blocking surface partially occludes the physiological cavity while allowing flow along the first orthogonal axis within the side branch vessel.

6. The implantable device of claim 5, where the body frame self-expands from a delivery condition to a deployed condition, a profile of the deployed condition being larger than a profile of the delivery condition.

7. The implantable device of claim 5, where the semi-occlusive blocking surface forms a curved surface when the blocking section is folded about the first axis.

8. The implantable device of claim 5, further comprising at least one anchoring element extending proximally from at least one of the first pair of anchoring segments and the second pair of anchoring segments.