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Irreversible electroporation to create tissue scaffolds

  • US 10,286,108 B2
  • Filed: 02/03/2017
  • Issued: 05/14/2019
  • Est. Priority Date: 04/29/2008
  • Status: Active Grant
First Claim
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1. An in vitro method of making an engineered tissue scaffold, said method comprising:

  • engineering a tissue scaffold by treating, in vitro, a tissue comprising cells and a native extracellular matrix with an electrical field;

    applying the electrical field in a manner and for a sufficient time at a sufficient power to cause irreversible electroporation of the cells; and

    producing an engineered tissue scaffold as a result of the irreversible electroporation.

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