Modified fluorinated nucleoside analogues
First Claim
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1. A method for the treatment of hepatitis C infection, which comprises:
- providing to a human subject in need thereof an antivirally effective amount of a (2′
R)-2′
-deoxy-2′
-fluoro-2′
-C-methyl nucleoside (β
-D) or its pharmaceutically acceptable salt of the structure;
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Abstract
The disclosed invention provides compositions and methods of treating a Flaviviridae infection, including hepatitis C virus, West Nile Virus, yellow fever virus, and a rhinovirus infection in a host, including animals, and especially humans, using a (2′R)-2′-deoxy-2′-fluoro-2′-C-methyl nucleosides, or a pharmaceutically acceptable salt or prodrug thereof.
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Citations
1 Claim
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1. A method for the treatment of hepatitis C infection, which comprises:
providing to a human subject in need thereof an antivirally effective amount of a (2′
R)-2′
-deoxy-2′
-fluoro-2′
-C-methyl nucleoside (β
-D) or its pharmaceutically acceptable salt of the structure;
Specification