Silk performance apparel and products and methods of preparing the same

• US 10,287,728 B2
• Filed: 06/10/2016
• Issued: 05/14/2019
• Est. Priority Date: 12/02/2014
• Status: Active Grant

• Current Assignee: Evolved by Nature, Inc.
• Original Assignee: Evolved by Nature, Inc.
• Inventors: Altman, Gregory H., Mortarino, Enrico
• Primary Examiner(s): Chriss, Jennifer A
• Assistant Examiner(s): Lopez, Ricardo E
• Application Number:
  US15/179,846
• Publication Number:
  US 20160281294A1
• Time in Patent Office: 1,068 Days
• CPC Class Codes: A41D 13/0015 Sports garments other than provided for in groups A41D13/0007 - A41D13/088
• CPC Class Codes: A41D 31/00 Materials specially adapted for outerwear
• CPC Class Codes: A41D 31/185 using layered materials
• CPC Class Codes: A61K 8/64 Proteins; Peptides; Derivatives or degradation products thereof
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: D06M 15/15 Proteins or derivatives thereof
• CPC Class Codes: D06M 2200/50 Modified hand or grip properties; Softening compositions
• CPC Class Codes: D06N 2203/02 Natural macromolecular compounds or derivatives thereof
• CPC Class Codes: D06N 7/00 Flexible sheet materials not otherwise provided for, e.g. textile threads, filaments, yarns or tow, glued on macromolecular material paper-based or board-based structures for surface covering D21H27/20
• CPC Class Codes: D10B 2401/02 Moisture-responsive characteristics

Abstract

Silk performance apparel and methods of preparing the same are disclosed herein. In some embodiments, silk performance apparel includes textiles, fabrics, consumer products, and other materials that are coated with aqueous solutions of pure silk fibroin-based protein fragments. In some embodiments, coated apparel products exhibit surprisingly improved moisture management properties and increased resistance to microbial growth.

Claims

1. An article comprising a fiber or yarn having a coating, wherein the coating comprises biocompatible silk fibroin based proteins or fragments thereof having an average weight average molecular weight ranging from about 5 kDa to about 80 kDa, wherein the biocompatible silk fibroin based proteins or fragments thereof comprise a polydispersity ranging from about 1 to about 5.0, and

wherein the proteins or protein fragments, prior to coating the fabric, do not spontaneously or gradually gelate and do not visibly change in color or turbidity when in an aqueous solution for at least 10 days.

2. The article of claim 1, wherein the article is a fabric.

3. The article of claim 1, wherein the biocompatible silk fibroin based proteins or fragments thereof comprise silk fibroin-based proteins or protein fragments having about 0.01% (w/w) to about 10% (w/w) sericin.

4. The article of claim 1, wherein the biocompatible silk fibroin based proteins or fragments thereof are selected from the group consisting of natural silk fibroin based proteins or fragments thereof, recombinant silk fibroin based proteins or fragments thereof, and combinations thereof.

5. The article of claim 4, wherein the biocompatible silk fibroin based proteins or fragments thereof are natural silk fibroin based proteins or fragments thereof that are selected from the group consisting of spider silk fibroin based proteins or fragments thereof, silkworm silk fibroin based proteins or fragments thereof, and combinations thereof.

6. The article of claim 5, wherein the biocompatible natural silk fibroin based proteins or fragments are silkworm silk fibroin based proteins or fragments thereof, and the silkworm silk fibroin based proteins or fragments thereof is Bombyx mori silk fibroin based proteins or fragments thereof.

7. The article of claim 1, wherein the biocompatible silk fibroin based proteins or fragments comprise silk and a copolymer.

8. The article of claim 1, wherein the biocompatible silk fibroin based proteins or protein fragments thereof have an average weight average molecular weight selected from the group consisting of about 6 kDa to about 16 kDa, about 17 kDa to about 38 kDa, and about 39 kDa to about 80 kDa.

9. The article of claim 1, wherein the fiber or yarn is selected from the group consisting of natural fiber or yarn, synthetic fiber or yarn, or combinations thereof.

10. The article of claim 9, wherein the fiber or yarn is natural fiber or yarn selected from the group consisting of cotton, alpaca fleece, alpaca wool, llama fleece, llama wool, cotton, cashmere, sheep fleece, sheep wool, and combinations thereof.

11. The article of claim 9, wherein the fiber or yarn is synthetic fiber or yarn selected from the group consisting of polyester, nylon, polyester-polyurethane copolymer, and combinations thereof.

12. The article of claim 2, wherein the fabric exhibits an improved property, wherein the improved property is an accumulative one-way moisture transport index selected from the group consisting of greater than 40%, greater than 60%, greater than 80%, greater than 100%, greater than 120%, greater than 140%, greater than 160%, and greater than 180%.

13. The article of claim 2, wherein the fabric exhibits an improved property, wherein the improved property is an accumulative one way transport capability increase relative to uncoated fabric selected from the group consisting of 1.2 fold, 1.5 fold, 2.0 fold, and 3.0 fold.

14. The article of claim 2, wherein the fabric exhibits an improved property, wherein the improved property is an overall moisture management capability selected from the group consisting of greater than 0.05, greater than 0.10, greater than 0.15, greater than 0.20, greater than 0.25, greater than 0.30, greater than 0.35, greater than 0.40, greater than 0.50, greater than 0.60, greater than 0.70, and greater than 0.80.

15. The article of claim 14, wherein the improved property is determined after a period of machine washing cycles selected from the group consisting of 5 cycles, 10 cycles, 25 cycles, and 50 cycles.

16. The article of claim 2, wherein the coating is applied to the fabric at the fiber level prior to forming the fabric.

17. The article of claim 2, wherein the coating is applied to the fabric at the fabric level.

18. The article of claim 17, wherein the fabric is bath coated.

19. The article of claim 17, wherein the fabric is spray coated.

20. The article of claim 17, wherein the fabric is coated with a stencil.

21. The article of claim 17, wherein the coating is applied to at least one side of the fabric using a method selected from the group consisting of a bath coating process, a spray coating process, a stencil process, a silk-foam based process, and a roller-based process.

22. The article of claim 1, wherein the coating has a thickness of about one nanolayer.

23. The article of claim 1, wherein the coating has a thickness selected from the group consisting of about 5 nm, about 10 nm, about 15 nm, about 20 nm, about 25 nm, about 50 nm, about 100 nm, about 200 nm, about 500 nm, about 1 μ

m, about 5 μ

m, about 10 μ

m, and about 20 μ

m.

24. The article of claim 2, wherein the coating is adsorbed on the fabric.

25. The article of claim 2, wherein the coating is attached to the fabric through chemical, enzymatic, thermal, or irradiative cross-linking.

26. The article of claim 17, wherein the hand of the coated fabric is improved relative to the uncoated fabric.

27. The article of claim 26, wherein the hand of the coated fabric that is improved is selected from the group consisting of softness, crispness, dryness, silkiness, and combinations thereof.

28. The article of claim 1, wherein the biocompatible silk fibroin based proteins or fragments thereof comprise a polydispersity ranging from about 1.5 to about 3.0.

29. The article of claim 1, wherein the biocompatible silk fibroin based proteins or fragments thereof comprise a polydispersity ranging from about 1.5 to about 2.0.

30. The article of claim 1, wherein the biocompatible silk fibroin based proteins or fragments thereof comprise a polydispersity ranging from about 2.0 to about 3.0.

31. An article comprising a fiber or yarn having a coating, wherein the coating comprises biocompatible silk fibroin based proteins or fragments thereof having an average weight average molecular weight ranging from about 5 kDa to about 10 kDa, wherein the biocompatible silk fibroin based proteins or fragments thereof comprise a polydispersity ranging from about 1 to about 5.0.