Reagents for directed biomarker signal amplification
DC CAFCFirst Claim
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1. A polymer-biomolecule conjugate comprising:
- a water soluble conjugated polymer; and
a biomolecule covalently linked to the water soluble conjugated polymer;
wherein the water soluble conjugated polymer is of the formula;
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Abstract
Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.
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Citations
20 Claims
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1. A polymer-biomolecule conjugate comprising:
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a water soluble conjugated polymer; and a biomolecule covalently linked to the water soluble conjugated polymer; wherein the water soluble conjugated polymer is of the formula; - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification