Biosignal measurement apparatus and biosignal measurement method

• US 10,292,600 B2
• Filed: 06/24/2014
• Issued: 05/21/2019
• Est. Priority Date: 07/06/2012
• Status: Expired due to Fees

• Current Assignee: Panasonic Intellectual Property Management Co., Ltd. (Panasonic Holdings Corporation)
• Original Assignee: Panasonic Intellectual Property Management Co., Ltd. (Panasonic Holdings Corporation)
• Inventors: Morikawa, Koji, Ozawa, Jun
• Primary Examiner(s): Jang, Christian
• Assistant Examiner(s): Kingsley, Sarah R
• Application Number:
  US14/313,176
• Publication Number:
  US 20140309540A1
• Time in Patent Office: 1,792 Days
• Field of Search: None
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/0809 by impedance pneumography
• CPC Class Codes: A61B 5/0826 Detecting or evaluating apnoea events A61B5/4818 takes precedence
• CPC Class Codes: A61B 5/25 Bioelectric electrodes therefor
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/364 Detecting abnormal ECG interval, e.g. extrasystoles, ectopic heartbeats
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61B 5/6804 Garments; Clothes

Abstract

A biosignal measurement apparatus includes: a potential difference measurement unit that measures a potential difference between a plurality of electrodes of an electrode unit placed on a user'"'"'s chest; an ECG analysis unit that obtains an electrocardiogram (ECG) indicating a temporal variation of a cardiac potential of the user, from the potential difference measured by the potential difference measurement unit; an impedance measurement switching unit that determines a start timing of a first period which is a period not including an R wave, using the ECG obtained by the ECG analysis unit; an impedance measurement unit that measures an impedance between the plurality of electrodes in the first period; and a respiratory calculation unit that calculates respiratory information related to respiration of the user, based on a temporal variation of the impedance measured by the impedance measurement unit.

Claims

1. A biosignal measurement apparatus comprising:

a potential difference measurement circuit configured to measure a potential difference between a plurality of electrodes placed on a user'"'"'s chest;

an impedance measurement circuit configured to measure an impedance between the plurality of electrodes in a first period for respiratory measurement of the user, the first period being a period not including an R wave;

a processor; and

a non-transitory computer-readable recording medium having stored thereon executable instructions, which when executed by the processor, cause the biosignal measurement apparatus to;

obtain a first electrocardiogram (ECG) indicating a temporal variation of a cardiac potential of the user, from the potential difference measured by the potential difference measurement circuit;

set a start timing of the first period using the obtained first ECG, the start timing of the first period being set based on a time of an R wave in a period of one heartbeat of the user, such that the first period is set in the period not including the R wave;

determine a length of the first period, based on a time interval between two adjacent R waves in the obtained first ECG;

receive a first time at which the R wave is detected most recently, and determine the length of the first period to cause the first period to be included between the first time and a time at which the time interval between the two adjacent R waves elapses from the first time;

measure a second ECG indicating a temporal variation of a cardiac potential of the user, from the potential difference measured by the potential difference measurement circuit in a second period which is a period including an R wave and not including the first period;

calculate respiratory information related to the respiration measurement of the user, based on a temporal variation of the impedance measured by the impedance measurement circuit;

calculate a heart rate of the user based on a time interval between two adjacent R waves in the obtained first ECG; and

output the calculated respiratory information, the calculated heart rate, and at least one of the first ECG and the second ECG for the diagnosing of diseases,

wherein the executable instructions, when executed by the processor, further cause the biosignal measurement apparatus to;

determine a start timing and a length of a preliminary measurement period which is a period for continuously measuring the cardiac potential of the user,

obtain the temporal variation of the cardiac potential of the user in the preliminary measurement period, from the potential difference measured by the potential difference measurement circuit in the preliminary measurement period, and

determine the start timing and the length of the first period, based on the temporal variation of the cardiac potential of the user in the preliminary measurement period, and

wherein the executable instructions, when executed by the processor, further cause the biosignal measurement apparatus to detect an abnormality of a P wave or an ST wave, based on the obtained temporal variation of the cardiac potential of the user in the preliminary measurement period, and

determine the start timing and the length of the first period, to cause the P wave or the ST wave having the detected abnormality and the R wave to be included in the second period.

2. The biosignal measurement apparatus according to claim 1,

wherein the executable instructions, when executed by the processor, further cause the biosignal measurement apparatus to determine the start timing of the first period to be when a predetermined time elapses based on the R wave in the obtained first ECG.

3. The biosignal measurement apparatus according to claim 1,

wherein the executable instructions, when executed by the processor, further cause the biosignal measurement apparatus to determine the start timing of the first period to be when a predetermined time elapses from a most recent time at which the R wave appears in the first ECG.

4. The biosignal measurement apparatus according to claim 1, wherein

a current is applied between the plurality of electrodes at the determined start timing, and

the impedance measurement circuit is configured to measure the impedance between the plurality of electrodes in the first period, based on the potential difference between the plurality of electrodes and a magnitude of the applied current.

5. A biosignal measurement method comprising:

measuring a potential difference between a plurality of electrodes placed on a user'"'"'s chest;

obtaining a first electrocardiogram (ECG) indicating a temporal variation of a cardiac potential of the user, from the measured potential difference;

setting a start timing of a first period for respiratory measurement of the user using the first ECG obtained during the obtaining step, the first period being a period not including an R wave, the start timing of the first period being set based on a time of an R wave in a period of one heartbeat of the user, such that the first period is set in the period not including the R wave;

determining a length of the first period, based on a time interval between two adjacent R waves in the first ECG obtained during the obtaining step;

receiving a first time at which the R wave is detected most recently, and determining the length of the first period to cause the first period to be included between the first time and a time at which the time interval between the two adjacent R waves elapses from the first time;

measuring a second ECG indicating a temporal variation of a cardiac potential of the user, from the potential difference measured in the measuring of the potential difference in a second period which is a period including an R wave and not including the first period;

measuring an impedance between the plurality of electrodes in the first period;

calculating respiratory information related to the respiration measurement of the user, based on a temporal variation of the impedance measured in the measuring of the impedance;

calculating a heart rate of the user based on a time interval between two adjacent R waves in the first ECG obtained during the obtaining step; and

outputting the respiratory information calculated in the calculating of the respiratory information, the heart rate calculated in the calculating of the heart rate, and at least one of the first ECG and the second ECG for the diagnosing of diseases,

wherein the biosignal measurement method further comprises;

determining a start timing and a length of a preliminary measurement period which is a period for continuously measuring the cardiac potential of the user,

obtaining the temporal variation of the cardiac potential of the user in the preliminary measurement period, from the potential difference measured by the potential difference measurement circuit in the preliminary measurement period, and

determining the start timing and the length of the first period, based on the temporal variation of the cardiac potential of the user in the preliminary measurement period, and

wherein the biosignal measurement method further comprises;

detecting an abnormality of a P wave or an ST wave, based on the obtained temporal variation of the cardiac potential of the user in the preliminary measurement period, and

determining the start timing and the length of the first period, to cause the P wave or the ST wave having the detected abnormality and the R wave to be included in the second period.

6. A non-transitory computer-readable recording medium for use in a computer, the recording medium having a computer program recorded thereon for causing the computer to execute the biosignal measurement method according to claim 5.

7. A biosignal measurement apparatus comprising:

a potential difference measurement circuit configured to measure a potential difference between a plurality of electrodes placed on a user'"'"'s chest;

an impedance measurement circuit configured to measure an impedance between the plurality of electrodes in a first period which is a period not including an R wave;

a processor; and

a non-transitory computer-readable recording medium having stored thereon executable instructions, which when executed by the processor, cause the biosignal measurement apparatus to;

obtain an electrocardiogram (ECG) indicating a temporal variation of a cardiac potential of the user, from the potential difference measured by the potential difference measurement circuit, wherein the obtained ECG includes the ECG being obtained from the potential difference measured by the potential difference measurement circuit in a second period which is a period including the R wave in the ECG and different from the first period, and includes a part in which the first period and the second period alternate;

determine a start timing of the first period, using the obtained ECG;

calculate respiratory information related to respiration of the user, based on a temporal variation of the impedance measured by the impedance measurement circuit;

obtain the temporal variation of the impedance between the plurality of electrodes, by temporally interpolating the impedance in the second period between the impedance measured in the first period preceding the second period and the impedance measured in the first period following the second period;

calculate the respiratory information based on a peak of a low frequency component of the obtained temporal variation of the impedance;

calculate a plurality of respiratory information candidates by performing the temporal interpolation;

calculate a heart rate of the user;

select, from the plurality of respiratory information candidates, a respiratory information candidate indicating a higher respiratory rate when the calculated heart rate is higher; and

output the selected respiratory information candidate as the respiratory information, the calculated heart rate and the obtained ECG for the diagnosing of diseases.

10. The biosignal measurement apparatus according to claim 7, wherein data corresponding to the calculated respiratory information and data corresponding to the calculated heart rate are obtained simultaneously via the plurality of electrodes.

8. A biosignal measurement apparatus comprising:

a potential difference measurement circuit configured to measure a potential difference between a plurality of electrodes placed on a user'"'"'s chest;

an impedance measurement circuit configured to measure an impedance between the plurality of electrodes in a first period which is a period not including an R wave;

a processor; and

a non-transitory computer-readable recording medium having stored thereon executable instructions, which when executed by the processor, cause the biosignal measurement apparatus to;

obtain an electrocardiogram (ECG) indicating a temporal variation of a cardiac potential of the user, from the potential difference measured by the potential difference measurement circuit, wherein the obtained ECG includes the ECG being obtained from the potential difference measured by the potential difference measurement circuit in a second period which is a period including the R wave in the ECG and different from the first period, and includes a part in which the first period and the second period alternate;

determine a start timing of the first period, using the obtained ECG;

calculate respiratory information related to respiration of the user, based on a temporal variation of the impedance measured by the impedance measurement circuit;

obtain the temporal variation of the impedance between the plurality of electrodes, by temporally interpolating the impedance in the second period between the impedance measured in the first period preceding the second period and the impedance measured in the first period following the second period;

calculate the respiratory information based on a peak of a low frequency component of the obtained temporal variation of the impedance;

calculate a plurality of respiratory information candidates by performing the temporal interpolation;

select, from the plurality of respiratory information candidates, a respiratory information candidate indicating a lower respiratory rate when an amplitude of the temporal variation of the measured impedance is higher; and

output the selected respiratory information candidate as the respiratory information and the obtained ECG for the diagnosing of diseases.

9. A biosignal measurement apparatus comprising:

a potential difference measurement circuit configured to measure a potential difference between a plurality of electrodes placed on a user'"'"'s chest;

an impedance measurement circuit configured to measure an impedance between the plurality of electrodes in a first period which is a period not including an R wave;

a processor; and

a non-transitory computer-readable recording medium having stored thereon executable instructions, which when executed by the processor, cause the biosignal measurement apparatus to;

obtain an electrocardiogram (ECG) indicating a temporal variation of a cardiac potential of the user, from the potential difference measured by the potential difference measurement circuit;

determine a start timing of the first period, using the obtained ECG;

calculate respiratory information related to respiration of the user, based on a temporal variation of the impedance measured by the impedance measurement circuit;

determine a start timing and a length of a preliminary measurement period which is a period for continuously measuring the cardiac potential of the user;

obtain the temporal variation of the cardiac potential of the user in the preliminary measurement period, from the potential difference measured by the potential difference measurement circuit in the preliminary measurement period;

determine the start timing and a length of the first period, based on the temporal variation of the cardiac potential of the user in the preliminary measurement period;

detect an abnormality of a P wave or an ST wave, based on the obtained temporal variation of the cardiac potential of the user in the preliminary measurement period;

determine the start timing and the length of the first period, to cause the P wave or the ST wave having the detected abnormality and the R wave to be included in a second period; and

output the calculated respiratory information and the obtained ECG for the diagnosing of diseases.

11. A biosignal measurement apparatus comprising:

a potential difference measurement circuit configured to measure a potential difference between a plurality of electrodes placed on a user'"'"'s chest;

an impedance measurement circuit configured to measure an impedance between the plurality of electrodes in a first period for respiratory measurement of the user, the first period being a period not including an R wave;

a processor; and

a non-transitory computer-readable recording medium having stored thereon executable instructions, which when executed by the processor, cause the biosignal measurement apparatus to;

obtain a first electrocardiogram (ECG) indicating a temporal variation of a cardiac potential of the user, from the potential difference measured by the potential difference measurement circuit;

set a start timing of the first period using the obtained first ECG, the start timing of the first period being set based on a time of an R wave in a period of one heartbeat of the user, such that the first period is set in the period not including the R wave;

determine a length of the first period, based on a time interval between two adjacent R waves in the obtained first ECG;

receive a first time at which the R wave is detected most recently, and determine the length of the first period to cause the first period to be included between the first time and a time at which the time interval between the two adjacent R waves elapses from the first time;

measure a second ECG indicating a temporal variation of a cardiac potential of the user, from the potential difference measured by the potential difference measurement circuit in a second period which is a period including an R wave and not including the first period;

calculate respiratory information related to the respiration measurement of the user, based on a temporal variation of the impedance measured by the impedance measurement circuit;

calculate a heart rate of the user based on a time interval between two adjacent R waves in the obtained first ECG;

output the calculated respiratory information, the calculated heart rate, and at least one of the first ECG and the second ECG for the diagnosing of diseases;

determine a start timing and a length of a preliminary measurement period which is a period for continuously measuring the cardiac potential of the user;

obtain the temporal variation of the cardiac potential of the user in the preliminary measurement period, from the potential difference measured by the potential difference measurement circuit in the preliminary measurement period;

determine the start timing and the length of the first period, based on the temporal variation of the cardiac potential of the user in the preliminary measurement period;

detect an abnormality of a P wave or an ST wave, based on the obtained temporal variation of the cardiac potential of the user in the preliminary measurement period; and

determine the start timing and the length of the first period, to cause the P wave or the ST wave having the detected abnormality and the R wave to be included in the second period.

12. A biosignal measurement method comprising:

measuring a potential difference between a plurality of electrodes placed on a user'"'"'s chest;

obtaining a first electrocardiogram (ECG) indicating a temporal variation of a cardiac potential of the user, from the measured potential difference;

setting a start timing of a first period for respiratory measurement of the user using the first ECG obtained, the first period being a period not including an R wave, the start timing of the first period being set based on a time of an R wave in a period of one heartbeat of the user, such that the first period is set in the period not including the R wave;

determining a length of the first period, based on a time interval between two adjacent R waves in the first ECG obtained;

receiving a first time at which the R wave is detected most recently, and determining the length of the first period to cause the first period to be included between the first time and a time at which the time interval between the two adjacent R waves elapses from the first time;

measuring a second ECG indicating a temporal variation of a cardiac potential of the user, from the potential difference measured in the measuring of the potential difference in a second period which is a period including an R wave and not including the first period;

measuring an impedance between the plurality of electrodes in the first period;

calculating respiratory information related to the respiration measurement of the user, based on a temporal variation of the impedance measured in the measuring of the impedance;

calculating a heart rate of the user based on a time interval between two adjacent R waves in the first ECG obtained;

outputting the respiratory information calculated in the calculating of the respiratory information, the heart rate calculated in the calculating of the heart rate, and at least one of the first ECG and the second ECG for the diagnosing of diseases;

determining a start timing and a length of a preliminary measurement period which is a period for continuously measuring the cardiac potential of the user;

obtaining the temporal variation of the cardiac potential of the user in the preliminary measurement period, from the potential difference measured by the potential difference measurement circuit in the preliminary measurement period;

determining the start timing and the length of the first period, based on the temporal variation of the cardiac potential of the user in the preliminary measurement period;

detecting an abnormality of a P wave or an ST wave, based on the obtained temporal variation of the cardiac potential of the user in the preliminary measurement period; and

determining the start timing and the length of the first period, to cause the P wave or the ST wave having the detected abnormality and the R wave to be included in the second period.