Blood flow index calculating method, blood flow index calculating apparatus, and recording medium

• US 10,292,602 B2
• Filed: 09/23/2015
• Issued: 05/21/2019
• Est. Priority Date: 03/29/2013
• Status: Active Grant

• Current Assignee: Fujitsu Limited
• Original Assignee: Fujitsu Limited
• Inventors: Sakata, Masato, Uchida, Daisuke, Inomata, Akihiro, Sekiguchi, Hidenori
• Primary Examiner(s): Koharski, Christopher
• Assistant Examiner(s): Bays, Pamela M.
• Application Number:
  US14/862,402
• Publication Number:
  US 20160007865A1
• Time in Patent Office: 1,336 Days
• CPC Class Codes: A61B 2576/00 Medical imaging apparatus involving image processing or analysis A61B1/00009, A61B6/52 and A61B8/52 take precedence; image processing per se G06T; details of algorithms for analysing medical images G06T7/0012
• CPC Class Codes: A61B 5/0077 Devices for viewing the surface of the body, e.g. camera, magnifying lens
• CPC Class Codes: A61B 5/02125 of pulse wave propagation time
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/1128 using image analysis A61B5/1127 takes precedence
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6898 Portable consumer electronic devices, e.g. music players, telephones, tablet computers
• CPC Class Codes: G06T 2207/30104 Vascular flow; Blood flow; Perfusion
• CPC Class Codes: G06T 7/0016 involving temporal comparison
• CPC Class Codes: G16H 30/40 for processing medical images, e.g. editing

Abstract

A blood flow index calculating method includes: obtaining, by a camera, an image capturing a first site of a living body and a second site of the living body; extracting an area of the first site of the living body and an area of the second site of the living body, by a processor; detecting a pulse wave pattern of the first site of the living body from the area of the first site of the living body and detecting a pulse wave pattern of the second site of the living body from the area of the second site of the living body, by the processor; first calculating a delay amount from the pulse wave pattern of the first site and the pulse wave pattern of the second site, by the processor; and second calculating an index related to blood flow by using the delay amount, by the processor.

Claims

1. A blood flow index calculating method comprising:

obtaining, by a camera, an image capturing a first site of a living body and a second site of the living body, the first site being a part of the living body of a subject, and the second site being a site different from the first site;

extracting an area of the first site of the living body and an area of the second site of the living body, the areas being included in the image, by a processor;

detecting a pulse wave pattern of the first site of the living body from the area of the first site of the living body and detecting a pulse wave pattern of the second site of the living body from the area of the second site of the living body, by the processor;

first calculating a delay amount between the pulse wave pattern of the first site of the living body and the pulse wave pattern of the second site of the living body, by the processor; and

second calculating an index related to blood flow by using the delay amount, by the processor, wherein the detecting includes;

extracting a component of a particular frequency band other than a frequency band that pulse waves are possibly in among respective wavelength components, for each of the wavelength components, by the processor, the particular frequency band being any frequency band other than a frequency band that pulse waves are possibly in;

calculating a correction coefficient for minimizing a component of the particular frequency band when a difference between signals of representative values of the respective wavelength components is computed by comparison between magnitudes of the components of the particular frequency band of the respective wavelength components, and wherein the component of the particular frequency band is minimized by the correction coefficient after the calculating, by the processor;

multiplying a signal value of at least one signal having the representative values as the respective wavelength components by the correction coefficient, by the processor; and

detecting a waveform of a signal in which the components of the particular frequency band have been offset with one another by calculation of the difference between the signals of the representative values of the respective wavelength components after the multiplication by the correction coefficient, by the processor.

2. The blood flow index calculating method according to claim 1, further including third calculating a similarity between the pulse wave pattern of the first site of the living body and the pulse wave pattern of the second site of the living body, by the processor, wherein

the first calculating includes executing the calculation of the delay amount when the similarity is equal to or greater than a predetermined threshold, by the processor.

3. The blood flow index calculating method according to claim 2, wherein the third calculating includes calculating the similarity by using a cross correlation function, by the processor.

4. The blood flow index calculating method according to claim 2, wherein the third calculating includes calculating a difference between a cycle of peaks obtained from the pulse wave pattern of the first site of the living body and a cycle of peaks obtained from the pulse wave pattern of the second site of the living body as the similarity, by the processor.

5. A non-transitory computer-readable recording medium storing a blood flow index calculating program that causes a computer to execute a process comprising:

obtaining, by a camera, an image capturing a first site of a living body and a second site of the living body, the first site being a part of the living body of a subject, and the second site being a site different from the first site;

extracting an area of the first site of the living body and an area of the second site of the living body, the areas being included in the image;

detecting a pulse wave pattern of the first site of the living body from the area of the first site of the living body and detecting a pulse wave pattern of the second site of the living body from the area of the second site of the living body;

first calculating a delay amount between the pulse wave pattern of the first site of the living body and the pulse wave pattern of the second site of the living body; and

second calculating an index related to blood flow by using the delay amount wherein the detecting includes;

extracting a component of a particular frequency band other than a frequency band that pulse waves are possibly in among respective wavelength components, for each of the wavelength components, the particular frequency band being any frequency band other than a frequency band that pulse waves are possibly in;

calculating a correction coefficient for minimizing a component of the particular frequency band when a difference between signals of representative values of the respective wavelength components is computed by comparison between magnitudes of the components of the particular frequency band of the respective wavelength components, and wherein the component of the particular frequency band is minimized by the correction coefficient after the calculating;

multiplying a signal value of at least one signal having the representative values as the respective wavelength components by the correction coefficient; and

detecting a waveform of a signal in which the components of the particular frequency band have been offset with one another by calculation of the difference between the signals of the representative values of the respective wavelength components after the multiplication by the correction coefficient.

6. The non-transitory computer-readable recording medium according to claim 5, wherein

the process further includes third calculating a similarity between the pulse wave pattern of the first site of the living body and the pulse wave pattern of the second site of the living body, and

the first calculating includes executing the calculation of the delay amount when the similarity is equal to or greater than a predetermined threshold.

7. The non-transitory computer-readable recording medium according to claim 6, wherein the third calculating includes calculating the similarity by using a cross correlation function.

8. The non-transitory computer-readable recording medium according to claim 6, wherein the third calculating includes calculating a difference between a cycle of peaks obtained from the pulse wave pattern of the first site of the living body and a cycle of peaks obtained from the pulse wave pattern of the second site of the living body as the similarity.

9. A blood flow index calculating apparatus comprising:

a processor configured to execute a process including;

obtaining, by a camera, an image capturing a first site of a living body and a second site of the living body, the first site being a part of the living body of a subject, and the second site being a site different from the first site;

extracting an area of the first site of the living body and an area of the second site of the living body, the areas being included in the image;

detecting a pulse wave pattern of the first site of the living body from the area of the first site of the living body and detecting a pulse wave pattern of the second site of the living body from the area of the second site of the living body;

first calculating a delay amount between the pulse wave pattern of the first site of the living body and the pulse wave pattern of the second site of the living body; and

second calculating an index related to blood flow by using the delay amount, wherein the detecting includes;

extracting a component of a particular frequency band other than a frequency band that pulse waves are possibly in among respective wavelength components, for each of the wavelength components, the particular frequency band being any frequency band other than a frequency band that pulse waves are possibly in;

calculating a correction coefficient for minimizing a component of the particular frequency band when a difference between signals of representative values of the respective wavelength components is computed by comparison between magnitudes of the components of the particular frequency band of the respective wavelength components, and wherein the component of the particular frequency band is minimized by the correction coefficient after the calculating;

multiplying a signal value of at least one signal having the representative values as the respective wavelength components by the correction coefficient; and

detecting a waveform of a signal in which the components of the particular frequency band have been offset with one another by calculation of the difference between the signals of the representative values of the respective wavelength components after the multiplication by the correction coefficient.

10. The blood flow index calculating apparatus according to claim 9, wherein

the process further includes third calculating a similarity between the pulse wave pattern of the first site of the living body and the pulse wave pattern of the second site of the living body, and

the first calculating includes executing the calculation of the delay amount when the similarity is equal to or greater than a predetermined threshold.

11. The blood flow index calculating apparatus according to claim 10, wherein the third calculating includes calculating the similarity by using a cross correlation function.

12. The blood flow index calculating apparatus according to claim 10, wherein the third calculating includes calculating a difference between a cycle of peaks obtained from the pulse wave pattern of the first site of the living body and a cycle of peaks obtained from the pulse wave pattern of the second site of the living body as the similarity.