Multi-stream data collection system for noninvasive measurement of blood constituents

• US 10,292,628 B1
• Filed: 01/29/2019
• Issued: 05/21/2019
• Est. Priority Date: 07/03/2008
• Status: Active Grant

• Current Assignee: Masimo Corporation
• Original Assignee: Masimo Corporation
• Inventors: Poeze, Jeroen, Lamego, Marcelo, Merritt, Sean, Dalvi, Cristiano, Vo, Hung, Bruinsma, Johannes, Lesmana, Ferdyan, Kiani, Massi Joe E., Olsen, Greg
• Primary Examiner(s): Winakur, Eric F
• Assistant Examiner(s): Liu, Chu Chuan
• Application Number:
  US16/261,326
• Publication Number:
  US 20190150800A1
• Time in Patent Office: 112 Days
• CPC Class Codes: A61B 2562/0233 Special features of optical sensors or probes classified in A61B5/00
• CPC Class Codes: A61B 2562/04 Arrangements of multiple sensors of the same type
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 2562/146 for optical coupling
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/02427 Details of sensor
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/4875 Hydration status, fluid retention of the body
• CPC Class Codes: A61B 5/6816 Ear lobe
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6829 Foot or ankle
• CPC Class Codes: A61B 5/6838 Clamps or clips
• CPC Class Codes: A61B 5/6843 Monitoring or controlling sensor contact pressure
• CPC Class Codes: A61B 5/70 Means for positioning the patient in relation to the detecting, measuring or recording means
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor

Abstract

The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

Claims

1. A noninvasive optical physiological sensor comprising:

a plurality of emitters configured to emit light into tissue of a user;

a plurality of detectors configured to detect light that has been attenuated by tissue of the user, wherein the plurality of detectors comprise at least four detectors;

a housing configured to house at least the plurality of detectors; and

a light permeable cover configured to be located between tissue of the user and the plurality of detectors when the noninvasive optical physiological sensor is worn by the user, wherein the cover comprises an outwardly protruding convex surface configured to cause tissue of the user to conform to at least a portion of the outwardly protruding convex surface when the noninvasive optical physiological sensor is worn by the user and during operation of the noninvasive optical physiological sensor, and wherein the plurality of detectors are configured to receive light passed through the outwardly protruding convex surface after attenuation by tissue of the user.

2. The noninvasive optical physiological sensor of claim 1, wherein the plurality of detectors are arranged on a two-dimensional surface of the housing.

3. The noninvasive optical physiological sensor of claim 2, wherein a first detector and a second detector of the plurality of detectors are arranged across from each other on opposite sides of a central point along a first axis, and a third detector and a fourth detector of the plurality of detectors are arranged across from each other on opposite sides of the central point along a second axis which is perpendicular to the first axis.

4. The noninvasive optical physiological sensor of claim 3, wherein the cover is comprised of a rigid material.

5. The noninvasive optical physiological sensor of claim 4, wherein the at least four detectors are evenly spaced from one another.

6. The noninvasive optical physiological sensor of claim 5, wherein the outwardly protruding convex surface is a single outwardly protruding convex surface.

7. An optical physiological measurement device comprising:

a plurality of emitters configured to emit light into tissue of a user;

a circular housing including a planar surface;

at least four detectors arranged on the planar surface of the circular housing, wherein the four detectors are arranged in a grid pattern; and

a light permeable cover of the circular housing, and wherein at least a portion of the cover comprises a protruding surface that is arranged to allow passage of light to the at least four detectors after attenuation by tissue of the user.

8. The optical physiological measurement device of claim 7, wherein the cover is configured to cause tissue of the user to conform to at least a portion of the protruding surface of the cover when the optical physiological measurement device is worn by the user.

9. The optical physiological measurement device of claim 8, wherein the four detectors are arranged in the grid pattern such that a first detector and a second detector are arranged across from each other on opposite sides of a central point along a first axis, and a third detector and a fourth detector are arranged across from each other on opposite sides of the central point along a second axis which is perpendicular to the first axis.

10. The optical physiological measurement device of claim 9, wherein the cover is comprised of a rigid material.

11. The optical physiological measurement device of claim 10, wherein the cover is configured to be positioned between the at least four detectors and tissue of a user when the optical physiological measurement device is worn by the user.

12. The optical physiological measurement device of claim 11, wherein the cover is configured to press against and at least partially deform tissue of the user when the optical physiological measurement device is worn by the user.

13. The optical physiological measurement device of claim 12, wherein the at least four detectors are evenly spaced from one another.

14. The optical physiological measurement device of claim 13, wherein the protruding surface of the cover comprises a single surface of the cover that covers the at least four detectors.

15. The optical physiological measurement device of claim 14, wherein the single surface of the cover comprises a convex surface.

16. The optical physiological measurement device of claim 15, wherein the optical physiological measurement device is configured to provide data useable for determining measurements of at least one of:

glucose, oxygen, oxygen saturation, methemoglobin, total hemoglobin, carboxyhemoglobin, or carbon monoxide.

17. The optical physiological measurement device of claim 15, wherein the optical physiological measurement device is configured to provide data useable for determining measurements of pulse rate.

18. The optical physiological measurement device of claim 7 further comprising:

a processor configured to;

receive one or more signals from the at least four detectors, the one or more signals indicative of a physiological parameter of a wearer of the optical physiological measurement device; and

output information indicative of measurements of the physiological parameter to a mobile phone.

19. The optical physiological measurement device of claim 18, further comprising a touch-screen display.

20. A noninvasive optical physiological sensor comprising:

a plurality of emitters configured to emit light into tissue of a user;

a plurality of detectors configured to detect light that has been attenuated by tissue of the user, wherein the plurality of detectors comprise at least four detectors;

a housing configured to house at least the plurality of detectors; and

a light permeable cover configured to be located between tissue of the user and the plurality of detectors when the noninvasive optical physiological sensor is worn by the user, wherein the cover comprises an outwardly protruding surface configured to cause tissue of the user to conform to at least a portion of the outwardly protruding surface when the noninvasive optical physiological sensor is worn by the user and during operation of the noninvasive optical physiological sensor, and wherein the outwardly protruding surface is further configured to allow passage of light to the plurality of detectors after attenuation by tissue of the user.

21. The noninvasive optical physiological sensor of claim 20, wherein the plurality of detectors are arranged on a two-dimensional surface of the housing.

22. The noninvasive optical physiological sensor of claim 21, wherein a first detector and a second detector of the plurality of detectors are arranged across from each other on opposite sides of a central point along a first axis, and a third detector and a fourth detector of the plurality of detectors are arranged across from each other on opposite sides of the central point along a second axis which is perpendicular to the first axis.

23. The noninvasive optical physiological sensor of claim 22, wherein the cover is comprised of a rigid material.

24. The noninvasive optical physiological sensor of claim 23, wherein the at least four detectors are evenly spaced from one another.

25. The noninvasive optical physiological sensor of claim 24, wherein the outwardly protruding surface comprises a single outwardly protruding surface configured to cover the plurality of detectors.

26. The noninvasive optical physiological sensor of claim 25, wherein the single outwardly protruding surface comprises is convex.

27. The noninvasive optical physiological sensor of claim 26, wherein the noninvasive optical physiological sensor is configured to provide data useable for determining measurements of at least one of:

glucose, oxygen, oxygen saturation, methemoglobin, total hemoglobin, carboxyhemoglobin, or carbon monoxide.

28. The noninvasive optical physiological sensor of claim 26, wherein the noninvasive optical physiological sensor is configured to provide data useable for determining measurements of pulse rate.

29. A physiological monitoring device comprising:

the invasive optical physiological sensor of claim 20; and

a processor configured to receive one or more signals from the plurality of detectors and communicate physiological measurement information to a mobile phone.

30. The physiological monitoring device of claim 29 further comprising a touch-screen display.