Electrolyte and pH monitoring for fluid removal processes
First Claim
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1. A method carried out by a blood fluid removal device or system, comprising:
- initiating blood fluid removal procedure for a patient in need thereof, wherein the procedure comprises use of a fluid selected from a dialysate fluid or a replacement fluid, and wherein the fluid has an initial pH buffer composition or electrolyte composition;
monitoring an indicator of blood electrolyte concentration or blood pH of the patient during the blood fluid removal session;
adjusting the pH buffer composition or the electrolyte composition of the fluid based on a rate of change of the monitored indicator;
monitoring the adjustments of pH or electrolyte concentration after adding the replacement fluid to the blood and prior to returning the blood to the patient; and
monitoring an indicator of the dialysate fluid after the dialysate fluid exits a blood fluid removal medium.
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Abstract
Methods include monitoring indicators of blood pH or blood electrolyte levels during a blood fluid removal session and adjusting concentrations of pH buffers or electrolytes in dialysate or replacement fluid used during the session based on the monitored indicators. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.
266 Citations
24 Claims
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1. A method carried out by a blood fluid removal device or system, comprising:
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initiating blood fluid removal procedure for a patient in need thereof, wherein the procedure comprises use of a fluid selected from a dialysate fluid or a replacement fluid, and wherein the fluid has an initial pH buffer composition or electrolyte composition; monitoring an indicator of blood electrolyte concentration or blood pH of the patient during the blood fluid removal session; adjusting the pH buffer composition or the electrolyte composition of the fluid based on a rate of change of the monitored indicator; monitoring the adjustments of pH or electrolyte concentration after adding the replacement fluid to the blood and prior to returning the blood to the patient; and monitoring an indicator of the dialysate fluid after the dialysate fluid exits a blood fluid removal medium. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method carried out by a blood fluid removal device or system, comprising:
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initiating blood fluid removal procedure for a patient in need thereof, wherein the procedure comprises use of a dialysate fluid and a dialysate membrane, as at least a part of a blood fluid removal medium, across which electrolytes may be exchanged between blood and the dialysate fluid; monitoring an indicator of blood electrolyte concentration or blood pH during the blood fluid removal session; and adjusting the flow rate of the dialysate fluid or blood based on a rate of change of the monitored indicator; monitoring adjustments of pH or electrolyte concentration prior to returning the blood to the patient; and monitoring an indicator of the dialysate fluid after the dialysate fluid exits the blood fluid removal medium. - View Dependent Claims (19, 20, 21, 22, 23, 24)
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Specification