Method apparatus and system for analyzing images

• US 10,299,686 B2
• Filed: 12/28/2008
• Issued: 05/28/2019
• Est. Priority Date: 03/28/2008
• Status: Active Grant

• Current Assignee: Real Imaging Ltd (Real Imaging Holdings Ltd.)
• Original Assignee: Real Imaging Ltd (Real Imaging Holdings Ltd.)
• Inventors: Arnon, Israel Boaz, Arieli, Yoel
• Primary Examiner(s): Abouelela, May A
• Application Number:
  US12/934,647
• Publication Number:
  US 20110021944A1
• Time in Patent Office: 3,803 Days
• Field of Search: 600474, 600473, 600315, 600549, 382154, 382128
• CPC Class Codes: A61B 5/015 By temperature mapping of body part

Abstract

A method of identifying a thermally distinguishable region in a living body is disclosed. The method comprises determining transient thermal history of a surface of the living body, and estimating a location or presence of the thermally distinguishable region in the living body based on the transient thermal history.

Claims

1. A method of identifying an internal thermally distinguishable region in a living body comprising:

operating a thermospatial imaging system for imaging the living body and generating and storing in a memory a first thermospatial image describing a section of the living body when the living body is at a first posture, and a second thermospatial image describing said section of the living body when the living body is at a second posture, wherein each thermospatial image is defined over a three-dimensional (3D) spatial image of said body and has thermal data associated with a surface of the 3D spatial image;

retrieving said thermospatial images from said memory;

using a data processor of a computing platform for calculating a deformation function which maps a first 3D shape of said section of the living body, corresponding to said first posture, to a second 3D shape of said section of the living body, corresponding to said second posture, to determine correspondence between sets of picture-elements belonging to said first and said second thermospatial images;

determining, by said computing platform, transient thermal variation for each picture-element in at least one set and storing said transient thermal variation in the memory; and

estimating, by said computing platform, a location or presence of the internal thermally distinguishable region in the living body based on said transient thermal variations and generating, by said computing platform, an output indicative of the internal thermally distinguishable region.

2. The method of claim 1, further comprising estimating, by said computing platform, a size of said internal thermally distinguishable region, based on said transient thermal variation.

3. The method of claim 1, further comprising comparing, by said computing platform, said transient thermal variation to a reference transient thermal history, so as to determine said presence of said internal thermally distinguishable region.

4. The method of claim 1, further comprising heating or cooling a surface of said section of the living body between said first and said second thermospatial images.

5. The method of claim 1, wherein said estimating said location of said internal thermally distinguishable region comprises determining, by said computing platform, amount of temperature change for each point of a plurality of points over a surface of said section of the living body.

6. The method of claim 5, wherein said estimating said location of said internal thermally distinguishable region comprises determining, by said computing platform, a temperature change rate for at least one point of said plurality of points.

7. The method of claim 6, wherein said estimating said location of said internal thermally distinguishable region comprises comparing, by said computing platform, a temperature change rate of one point of said plurality of points to a temperature change rate of another point of said plurality of points.

8. The method of claim 5, wherein said estimating said location of said internal thermally distinguishable region comprises determining, by said computing platform, onset of a steady thermal state for at least one point of said plurality of points.

9. The method of claim 5, wherein said estimating said location of said internal thermally distinguishable region comprises determining, by said computing platform, onset of temperature change for at least one point of said plurality of points.

10. The method of claim 1, further comprising estimating, by said computing platform, characteristic heat conduction of said section of the living body based on said first thermospatial image and said second thermospatial image.

11. The method of claim 1, wherein said section of the living body is a breast of a woman.

12. The method of claim 1, further comprising determining, by said computing platform and based on said transient thermal variation, whether a point on said section of the living body corresponding to said picture-element has moved closer to or farther from the internal thermally distinguishable region between said first posture and said second posture, wherein said estimating said location or presence of the internal thermally distinguishable region is based on whether said point is closer to or farther from the internal thermally distinguishable region.

13. A method of treating a tumor in a body section, the tumor being the internal thermally distinguishable region of claim 2, the method comprising:

(a) executing the method of claim 2 to estimate a size of the tumor;

(b) applying a destructive treatment to the tumor; and

(c) executing the method of claim 2 to re-estimate said size.

14. The method of claim 13, further comprising repeating said (b) and said (c) until said size satisfies a predetermined criterion.

15. A method of monitoring evolution of a tumor in a body section, the tumor being the internal thermally distinguishable region of claim 2, the method comprising executing the method of claim 2 a plurality of times to estimate a size of the tumor at each execution, thereby monitoring the evolution of the tumor.

16. Apparatus for locating an internal thermally distinguishable region within a living body, comprising:

an input for receiving a first thermospatial image describing a section of the living body when the living body is at a first posture, and a second thermospatial image describing said section of a living body, wherein each thermospatial image is defined over a three-dimensional (3D) spatial image of said body and has thermal data associated with a surface of the 3D spatial image; and

a computing platform configured for calculating a deformation function which maps a first 3D shape of said section of the living body, corresponding to said first posture, to a second 3D shape of said section of the living body, corresponding to said second posture, to determine correspondence between sets of picture-elements belonging to said first and said second thermospatial images, determining by the computing platform, transient thermal variation for each picture-element in at least set, and estimating, by the computing platform, a location or presence of the internal thermally distinguishable region in said section of the living body based on said transient thermal variations.

17. The apparatus or system of claim 16, wherein said computing platform is configured for estimating a size of said internal thermally distinguishable region, based on said transient thermal variation.

18. The apparatus or system of claim 16, wherein said computing platform is configured for comparing said transient thermal variation to a reference transient thermal history, so as to determine said presence of said internal thermally distinguishable region.

19. The apparatus of claim 16, wherein said computing platform is configured for estimating characteristic heat conduction of said section of the living body based on said first thermospatial image and said second thermospatial image.

20. The apparatus of claim 16, wherein said computing platform configured for determining, based on said transient thermal variation, whether a point on said section of the living body corresponding to said picture-element has moved closer to or farther from the internal thermally distinguishable region between said first posture and said second posture, wherein said estimating said location or presence of the internal thermally distinguishable region is based on whether said point is closer to or farther from the internal thermally distinguishable region.

21. An imaging and processing system, comprising the apparatus of claim 16 and a thermospatial imaging system operable to provide said input unit with said thermospatial images.