Dual electrode system for a continuous analyte sensor

• US 10,299,712 B2
• Filed: 09/05/2017
• Issued: 05/28/2019
• Est. Priority Date: 12/05/2003
• Status: Active Grant

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Brister, Mark C., Petisce, James R., Simpson, Peter C.
• Primary Examiner(s): Jang, Christian
• Application Number:
  US15/695,932
• Publication Number:
  US 20170360341A1
• Time in Patent Office: 630 Days
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: B33Y 80/00 Products made by additive manufacturing

Abstract

Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.

Claims

1. An implantable continuous glucose sensor comprising:

an elongated body configured to be transcutaneously implanted into a host, wherein the elongated body is bendable prior to sensor insertion into the host, the elongated body comprising;

a substrate;

a first sensor element covering at least a first portion of the substrate;

a second sensor element covering at least a second portion of the substrate;

a third sensor element covering a third portion of the substrate, wherein the first portion, the second portion, and the third portion are different; and

a polymer membrane disposed over at least one of the first sensor element, the second sensor element, or the third sensor element, wherein the polymer membrane comprises an enzyme-containing domain;

wherein the first sensor element, the second sensor element, and the third sensor element all share a same axis, wherein the same axis is the axis of sensor insertion; and

wherein at least one of the first sensor element, the second sensor element, or the third sensor element is in contact with the polymer membrane.

2. The sensor of claim 1, wherein the polymer membrane comprises a first domain, wherein the first domain is an outermost domain and is configured to provide an interface with biological fluid, wherein the first domain comprises silicone-containing polyurethane polymer.

3. The sensor of claim 1, wherein at least one of the first sensor element, second sensor element, or third sensor element comprises an electrode.

4. The sensor of claim 1, wherein at least one of the first sensor element, second sensor element, or third sensor element comprises a working electrode.

5. The sensor of claim 1, wherein at least one of the first sensor element, second sensor element, or third sensor element comprises a reference electrode.

6. The sensor of claim 1, wherein at least one of the first sensor element, second sensor element, or third sensor element comprises a counter electrode.