Clot retrieval device for removing clot from a blood vessel

• US 10,299,811 B2
• Filed: 11/02/2015
• Issued: 05/28/2019
• Est. Priority Date: 03/09/2011
• Status: Active Grant

• Current Assignee: Neuravi Limited (Johnson & Johnson)
• Original Assignee: Neuravi Limited (Johnson & Johnson)
• Inventors: Brady, Eamon, Gilvarry, Michael, Razavi, Mahmood K., Vale, David, Griffin, Patrick, Casey, Brendan, McNamara, Jason
• Primary Examiner(s): Nguyen, Tuan V
• Application Number:
  US14/930,167
• Publication Number:
  US 20160120558A1
• Time in Patent Office: 1,303 Days
• CPC Class Codes: A61B 17/22031 Gripping instruments, e.g. forceps, for removing or smashing calculi A61B17/221 takes precedence
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22094 for crossing total occlusions, i.e. piercing
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2230/0091 helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
• CPC Class Codes: A61F 2230/0093 Umbrella-shaped, e.g. mushroom-shaped

Abstract

A clot retrieval device (9501) for removing clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration.

Claims

1. A method of removing clot from a vessel, the method comprising:

delivering a clot retrieval device across the clot, wherein the clot retrieval device includes;

an inner body having a collapsed delivery configuration and an expanded deployed configuration; and

an outer body extending along a longitudinal axis and at least partially overlying the inner body, wherein the outer body comprises

a first scaffolding section,

a second scaffolding section connected distal of the first scaffolding section by a hinged strut element, and

a clot inlet mouth between the first and second scaffolding section;

the first and second scaffolding sections of the outer body being expandable to a radial extent which is greater than the radial extent of the inner body in the deployed configuration to define a clot reception space between the inner body and the separate first and second scaffolding sections;

expanding the clot retrieval device so that one or both of the first scaffolding section and the second scaffolding section longitudinally urge at least a portion of the clot through the clot inlet mouth into the clot reception space; and

inhibiting migration of the clot into the inner body to allow a flow of blood through the inner body in the expanded deployed configuration.

2. The method of claim 1, wherein the outer body further includes a third scaffolding section positioned between the first scaffolding section and the second scaffolding section, wherein the third scaffolding is connected distal of the first scaffolding section by a second hinged strut element.

3. The method of claim 2, wherein the clot inlet mouth is a first clot inlet mouth, the first clot inlet mouth being positioned between the first scaffolding section and the third scaffolding section, the outer body further defining a second clot inlet mouth positioned between the third scaffolding section and the second scaffolding section.

4. The method of claim 3, wherein expanding the clot retrieval device includes expanding the clot retrieval device so that at least one of the first scaffolding section, the third scaffolding section, and the second scaffolding section deform at least a portion of the clot, the deformation forcing a portion of the clot through at least one of the first clot inlet mouth and the second clot inlet mouth into the clot reception space.

5. The method of claim 1, wherein a distal end of the outer body includes a distal capture net.

6. The method of claim 1, wherein a diameter of the first and second scaffolding sections of the outer body in the deployed configuration is between 2 and 18 times larger than a diameter of the first and second scaffolding sections of the outer body in the collapsed delivery configuration.

7. The method of claim 1, wherein each of the first scaffolding section and the second scaffolding section comprise a plurality struts in the form of closed cells.

8. A method of removing clot from a vessel, the method comprising:

delivering a clot retrieval device across the clot, wherein the clot retrieval device includes;

an inner body having a collapsed delivery configuration and an expanded deployed configuration; and

an outer body extending along a longitudinal axis and positioned at least partially about the inner body, wherein the outer body comprises

a first scaffolding section,

a second scaffolding section connected distal of the first scaffolding section by a hinged strut element, and

a clot inlet mouth between the first and second scaffolding section;

the first and second scaffolding sections of the outer body being expandable to a radial extent which is greater than the radial extent of the inner body in the deployed configuration to define a clot reception space between the inner body and the separate first and second scaffolding sections;

urging the clot in a direction along the longitudinal axis of the clot retrieval device so as to direct at least a portion of the clot through the clot inlet mouth into the clot reception space; and

inhibiting migration of the clot into the inner body to allow a flow of blood through the inner body in the expanded deployed configuration.

9. The method of claim 8, wherein the outer body further includes a third scaffolding section positioned between the first scaffolding section and the second scaffolding section, wherein the third scaffolding is connected distal of the first scaffolding section by a second hinged strut element.

10. The method of claim 9, wherein the clot inlet mouth is a first clot inlet mouth, the first clot inlet mouth being positioned between the first scaffolding section and the third scaffolding section, the outer body further defining a second clot inlet mouth positioned between the third scaffolding section and the second scaffolding section.

11. The method of claim 10, wherein urging the clot in a direction along the longitudinal axis of the clot retrieval device includes urging the clot in a direction along the longitudinal axis of the clot retrieval device so as to direct at least a portion of the clot through at least one of the first clot inlet mouth and the second clot inlet mouth into the clot reception space.

12. The method of claim 8, wherein a distal end of the outer body includes a distal capture net.

13. The method of claim 8, wherein urging the clot in a direction along the longitudinal axis of the clot retrieval device includes deforming the clot.

14. The method of claim 8, wherein a diameter of the first and second scaffolding sections of the outer body in the deployed configuration is between 2 and 18 times larger than a diameter of the first and second scaffolding sections of the outer body in the collapsed delivery configuration.

15. The method of claim 8, wherein each of the first scaffolding section and second scaffolding section comprise a plurality struts in the form of closed cells.

16. A method of removing clot from a vessel, the method comprising:

delivering a clot retrieval device across the clot, wherein the clot retrieval device includes;

an inner body having a collapsed delivery configuration and an expanded deployed configuration; and

an outer body extending along a longitudinal axis and at least partially overlying the inner body, wherein the outer body comprises

a first scaffolding section,

a second scaffolding section connected distal of the first scaffolding section by a first hinged strut element,

a first clot inlet mouth between the first and second scaffolding sections;

a third scaffolding section connected distal of the second scaffolding section by a second hinged strut element,

a second clot inlet mouth between the second and third scaffolding sections;

the scaffolding sections of the outer body being expandable to a radial extent which is greater than the radial extent of the inner body in the deployed configuration to define a clot reception space between the inner body and the scaffolding sections;

expanding the clot retrieval device so that one or more of the first, third, and second scaffolding sections deform at least a portion of the clot, the deforming forcing a portion of the clot through at least one of the first and second clot inlet mouths into the clot reception space; and

inhibiting migration of the clot into the inner body to allow a flow of blood through the inner body in the expanded deployed configuration.

17. The method of claim 16, wherein a distal end of the outer body includes a distal capture net.

18. The method of claim 16, wherein a diameter of the first, second, and third scaffolding sections of the outer body in the deployed configuration is between 2 and 18 times larger than a diameter of the first, second, and third scaffolding sections of the outer body in the collapsed delivery configuration.

19. The method of claim 16, wherein each of the first scaffolding section and second scaffolding section comprise a plurality struts in the form of closed cells.