Two-stage collapsible/expandable prosthetic heart valves and anchoring systems

• US 10,299,919 B2
• Filed: 03/22/2017
• Issued: 05/28/2019
• Est. Priority Date: 09/28/2007
• Status: Active Grant

• Current Assignee: St. Jude Medical (Abbott Laboratories Incorporated)
• Original Assignee: St. Jude Medical (Abbott Laboratories Incorporated)
• Inventors: Alkhatib, Yousef F.
• Primary Examiner(s): Gherbi, Suzette J
• Application Number:
  US15/466,182
• Publication Number:
  US 20170189180A1
• Time in Patent Office: 797 Days
• Field of Search: 623 21- 219
• CPC Class Codes: A61F 2/2403 with pivoting rigid closure members check valves with hinged closure members in general F16K15/03
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2433 using balloon catheter
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0076 ellipsoidal or ovoid
• CPC Class Codes: A61F 2250/006 modular
• CPC Class Codes: A61F 2250/0069 Sealing means

Abstract

A prosthetic heart valve includes a stent having an expanded configuration and a collapsed configuration, the stent in the expanded configuration having a longitudinal axis, an inflow end, an outflow end, a first portion adjacent the inflow end and a second portion adjacent the outflow end. The first portion includes a plurality of collapsible cells each having a perimeter and an open center; and the second portion includes a plurality of struts spaced from one another in an annular direction of the stent, the second portion of the stent being devoid of structure between annularly adjacent ones of the struts, whereby the annularly adjacent ones of the struts are not directly connected to one another. A valve assembly is supported by the stent.

Claims

1. A prosthetic valve, comprising:

a stent having an expanded configuration and a collapsed configuration, the stent in the expanded configuration having a longitudinal axis, an inflow end, an outflow end, a first portion adjacent the inflow end, and a second portion adjacent the outflow end, the first portion including a plurality of collapsible cells each having a perimeter and an open center, and the second portion including a plurality of struts spaced from one another in an annular direction of the stent, each of the struts extending from the first portion to a free end not connected to any structure, the second portion of the stent being devoid of structure between annularly adjacent ones of the struts, whereby the annularly adjacent ones of the struts are not directly connected to one another; and

a valve assembly supported by the stent.

2. The prosthetic valve as claimed in claim 1, wherein the second portion of the stent bulges radially outwardly relative to the first portion of the stent.

3. The prosthetic valve as claimed in claim 1, wherein the first portion of the stent in the expanded configuration defines a first radius from the longitudinal axis, and the second portion of the stent in the expanded condition defines a second radius from the longitudinal axis, the second radius being greater than the first radius.

4. The prosthetic valve as claimed in claim 1, wherein the first portion of the stent inclines radially outwardly in a direction toward the inflow end.

5. The prosthetic heart valve as claimed in claim 1, wherein the stent includes a first stent section separable from a second stent section, the second stent section being adapted for engagement with the first stent section in an assembled position.

6. The prosthetic valve as claimed in claim 5, wherein the second stent section includes a plurality of circumferentially spaced commissure post structures.

7. The prosthetic valve as claimed in claim 5, wherein the second stent section includes a plurality of projections, each projection extending radially outwardly into a respective one of the cells in the assembled position.

8. The prosthetic valve as claimed in claim 5, wherein the valve assembly includes a plurality of leaflets.

9. The prosthetic valve as claimed in claim 8, wherein the plurality of leaflets includes three leaflets.

10. The prosthetic valve as claimed in claim 8, wherein the valve assembly further includes a fabric cuff positioned between the plurality of leaflets and the second stent section in the assembled position.

11. The prosthetic valve as claimed in claim 8, wherein the valve assembly further includes a fabric cuff positioned around the outside of the first portion of the stent.

12. The prosthetic valve as claimed in claim 8, wherein the plurality of leaflets are made of a material selected from the group consisting of biological tissue, metals, polymers and mesh-reinforced polymers.

13. The prosthetic valve as claimed in claim 8, wherein the plurality of leaflets are formed from biological tissue.

14. The prosthetic valve as claimed in claim 8, further comprising:

an annular cuff secured to at least one of the stent or the valve assembly.