Device for harvesting, processing and transferring adipose tissue

• US 10,300,183 B2
• Filed: 02/02/2016
• Issued: 05/28/2019
• Est. Priority Date: 05/30/2012
• Status: Active Grant

• Current Assignee: Lifecell Corporation (Abbvie Incorporated)
• Original Assignee: Lifecell Corporation (Abbvie Incorporated)
• Inventors: Park, Sangwook, Connor, Jerome, Barere, Aaron
• Primary Examiner(s): Kwak, Dean
• Application Number:
  US15/013,111
• Publication Number:
  US 20160144086A1
• Time in Patent Office: 1,211 Days
• Field of Search: 422534, 422536, 422547, 422 681, 422535, 604540, 604542, 604 401, 604 609, 604319, 436174, 436175, 436177, 436178, 4353081, 435325, 210348, 424520
• CPC Class Codes: A61M 1/63 with means for emptying the suction container, e.g. by interrupting suction
• CPC Class Codes: A61M 1/79 Filters for solid matter specially adapted for dental use A61C17/065
• CPC Class Codes: A61M 1/892 with treatment of the collected fat
• CPC Class Codes: A61M 1/895 with means for reinjection of collected fat
• CPC Class Codes: A61M 2202/08 Lipoids
• CPC Class Codes: A61M 2205/75 with filters
• CPC Class Codes: A61M 5/00 Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests vaccination appliances for veterinary use A61D1/025 ; tube connectors, tube couplings, valves or branch units specially adapted for medical use A61M39/00; containers specially adapted for medical or pharmaceutical purposes A61J1/00; combinations of vial and syringe for mixing or transferring their contents A61J1/20; holders for containers for collecting, storing or administering blood or medical fluids A61J1/16

Abstract

The present disclosure provides devices and methods for harvesting and processing tissue from patients for grafting. The devices can include a tissue collection chamber for ascetically collecting, processing, and/or re-implanting adipose tissue.

Claims

1. A device for preparing tissue, the device comprising:

a main container having at least one inner surface and a bottom wall;

a filter comprising a sloped wall and a peripheral rim portion, wherein the filter is positioned within the main container such that the peripheral rim portion engages the at least one inner surface of the main container to define a first tissue collection chamber and a second filtrate collection chamber, and wherein the filter sloped wall is attached to the bottom wall;

at least one port passing through a portion of the bottom wall and in fluid communication with the first tissue collection chamber and an exterior of the main container, the at least one port having an opening within the first tissue collection chamber; and

a flexible membrane having a periphery, the periphery of the flexible membrane attached to at least one of the filter and the at least one inner surface of the main container to define the first tissue collection chamber as a space between the flexible membrane and the sloped wall of the filter, and wherein the flexible membrane has sufficient flexibility to allow expansion of the flexible membrane into the first tissue collection chamber to force at least a portion of a tissue that may be contained in the first tissue collection chamber through the at least one port.

2. The device of claim 1, further comprising at least one port in fluid communication with a space between the flexible membrane and the at least one inner surface of the main container.

3. The device of claim 1, further comprising at least one additional port having an opening located within the second filtrate collection chamber.

4. The device of claim 3, further comprising a negative pressure source in fluid communication with the at least one additional port.

5. The device of claim 4, wherein the negative pressure source is a vacuum.

6. The device of claim 3, further comprising a negative pressure source in fluid communication with the second filtrate collection chamber.

7. The device of claim 1, wherein the at least one port in fluid communication with the first tissue collection chamber comprises a valve configured to enable bidirectional flow.

8. The device of claim 1, further comprising a pressure measuring element.

9. The device of claim 1, wherein the sloped wall of the filter comprises a rigid material.

10. The device of claim 9, wherein the sloped wall of the filter comprises a material selected from a group consisting of medical grade plastic, biocompatible plastic, fiberglass, or medical grade metals.

11. The device of claim 10, wherein the sloped wall of the filter comprises stainless steel.

12. The device of claim 1, wherein the sloped wall of the filter has a downwardly sloped side surface angled towards a center of the main container.

13. The device of claim 1, wherein the flexible membrane comprises an elastomeric material.

14. The device of claim 1, wherein the flexible membrane is made from silicone.

15. The device of claim 1, further comprising a tissue suction instrument operably connected to the first tissue collection chamber.

16. The device of claim 1, further comprising a tissue transfer or delivery instrument operably connected to the device.

17. The device of claim 16, wherein the tissue transfer or delivery instrument comprises a flexible tube that is operably connected to the device.

18. The device of claim 1, wherein the tissue transfer or delivery instrument comprises a syringe that is operably connected to the device.

19. The device of claim 1, further comprising a tissue washing fluid source in fluid communication with the first tissue collection chamber.

20. The device of claim 19, wherein the tissue washing fluid source includes a material selected from a group consisting of ringer'"'"'s lactate, detergent, collagenase, or pH buffers.

21. The device of claim 16, wherein the tissue transfer or delivery instrument comprises a cannula that is operably connected to the device.