Antibody agents specific for human CD19 and uses thereof
First Claim
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1. An antibody agent that specifically binds human cluster of differentiation 19 (CD19), wherein the antibody agent comprises heavy chain variable region (HCVR) of 131-260 segment of SEQ ID NO:
- 42 and light chain variable region (LCVR) of 1-109 segment of SEQ ID NO;
42.
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Abstract
Described herein are human antibody agents and multi-specific binding agents that specifically bind human CD 19, in particular, native human CD 19. Also provided herein are methods of using the same or compositions thereof for the detection, prevention and/or therapeutic treatment of diseases characterized by CD 19 expression, in particular, B cell lymphomas and leukemias.
11 Citations
19 Claims
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1. An antibody agent that specifically binds human cluster of differentiation 19 (CD19), wherein the antibody agent comprises heavy chain variable region (HCVR) of 131-260 segment of SEQ ID NO:
- 42 and light chain variable region (LCVR) of 1-109 segment of SEQ ID NO;
42. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
- 42 and light chain variable region (LCVR) of 1-109 segment of SEQ ID NO;
Specification