Monitoring system and probe

• US 10,307,074 B2
• Filed: 04/17/2008
• Issued: 06/04/2019
• Est. Priority Date: 04/20/2007
• Status: Active Grant

• Current Assignee: ImpediMed Limited
• Original Assignee: ImpediMed Limited
• Inventors: Ward, Leigh Cordwin
• Primary Examiner(s): Hindenburg, Max F
• Application Number:
  US12/596,833
• Publication Number:
  US 20100152605A1
• Time in Patent Office: 4,065 Days
• Field of Search: 600547
• CPC Class Codes: A61B 2562/0215 Silver or silver chloride containing
• CPC Class Codes: A61B 2562/0217 Electrolyte containing
• CPC Class Codes: A61B 2562/043 in a linear array
• CPC Class Codes: A61B 5/0537 Measuring body composition by impedance, e.g. tissue hydration or fat content
• CPC Class Codes: A61B 5/4878 Evaluating oedema

Abstract

A probe for use in performing impedance measurements on a subject. The probe includes a housing for being held by an operator in use, a contact surface for contacting the subject and a connector for connecting the contact surface to a measuring device.

Claims

1. An apparatus comprising:

a signal generator;

a sensor;

a pair of first electrodes coupled to the signal generator, the pair of first electrodes independently positionable on different limbs of a subject; and

a pair of second electrodes coupled to the sensor, the pair of second electrodes positionable on different limbs of the subject,

wherein the pair of second electrodes includes a probe for use in performing impedance measurements on a subject, the probe comprising;

a) a housing configured to be held by an operator in use;

b) a contact surface for contacting the subject, wherein the contact surface includes a moving member for moving relative to the subject, and wherein the moving member is movably mounted to the housing and is configured to roll within the housing and along a tissue surface of the subject;

c) a connector for connecting the contact surface to the apparatus; and

,

d) a position sensor for sensing movement of the moving member, wherein the position sensor is configured to transmit information indicative of the position of the probe; and

wherein, in use, the probe is moved along a segment of the subject to thereby allow an impedance profile representing variations in impedance along the segment to be determined.

2. The apparatus according to claim 1, wherein the housing is an elongate housing, the contact surf ace is provided at a first end of the housing and the connector is provided at a second opposing end of the housing.

3. The apparatus according to claim 1, wherein the housing is formed from an insulating material.

4. The apparatus according to claim 1, wherein the housing is formed from a poly(methyl) methacrylate tube.

5. The apparatus according to claim 1, wherein the contact surface has a convex shape.

6. The apparatus according to claim 1, wherein the moving member is a roller ball, and wherein the housing includes a shaped mounting for receiving the roller ball.

7. The apparatus according to claim 1, wherein the moving member is a cylindrical roller mounted on an axle.

8. The apparatus according to claim 1, wherein the probe includes a contact for electrically connecting the moving member to the connecter.

9. The apparatus according to claim 8, wherein the contact is a spring.

10. The apparatus according to claim 1, wherein the position sensor for sensing movement of the moving member includes at least one of:

a) an optical sensor; and

b) moving elements in contact with the moving member.

11. The apparatus according to claim 1, wherein the connector is for connecting to a lead of the apparatus.

12. The apparatus according to claim 1, wherein, in use, the probe is connected to a processing system for:

a) causing at least one electrical signal to be applied to the subject via the pair of first electrodes provided on the subject; and

b) determining an indication indicative of at least one second electrical signal measured via the second pair of electrodes positioned on the subject including via the probe.

17. The apparatus according to claim 1, wherein the probe is for use in diagnosing oedema in a body segment of the subject.

13. A method of performing impedance measurements on a subject using an apparatus, the apparatus comprising:

a signal generator;

a sensor;

a pair of first electrodes coupled to the signal generator, the pair of first electrodes independently positionable on different limbs of a subject; and

a pair of second electrodes coupled to the sensor, the pair of second electrodes positionable on different limbs of the subject,

wherein the pair of second electrodes includes a probe comprising a housing configured to be held by an operator in use, a contact surf ace for contacting the subject wherein the contact surface includes a moving member for moving relative to the subject and wherein the moving member is movably mounted to the housing and is configured to roll within the housing and along a tissue surface of the subject, a connector for connecting the contact surface to the apparatus, and a position sensor for sensing movement of the moving member wherein the position sensor is configured to sense rolling motion of the moving member with respect to the housing,

the method, comprising;

a) positioning the probe in contact with a segment of the subject, the segment being on a limb of the subject;

b) causing the apparatus to perform a sequence of impedance measurements; and

c) moving the probe along the segment during the sequence of impedance measurements so that the apparatus;

i) determines positional information along different positions on the segment using the position sensor;

ii) determines impedance measurements along different positions on the segment, at least some of the impedance measurements correlated with positional information; and

iii) uses the impedance measurements to determine an impedance profile.

14. The method according to claim 13, wherein the method further includes displaying a representation of the impedance profile to thereby allow the impedance profile to be used in determining a presence, absence, degree or location of oedema in the subject.

15. The method according to claim 13, wherein the method includes:

a) causing a sequence of first electrical signals to be applied to the subject via the pair of first electrodes provided on the subject connected to the signal generator; and

b) determining an indication of a sequence of second electrical signals measured via the pair of second electrodes positioned on the subject including via the probe.

16. The method according to claim 15, wherein the method includes:

using an indication of the first and second signals to determine the impedance profile, the impedance profile representing variations in measured impedance along the segment.

18. A method of diagnosing oedema in a body segment of a subject using a measuring device, the measuring device comprising:

a signal generator;

a sensor;

a pair of first electrodes coupled to the signal generator, the pair of first electrodes independently positionable on different limbs of a subject; and

a pair of second electrodes coupled to the sensor, the palf of second electrodes positionable on different limbs of the subject,

wherein the pair of second electrodes includes a probe, the probe comprising a housing configured to be held by an operator in use, a contact surface for contacting the subject wherein the contact surface includes a moving member for moving relative to the subject and wherein the moving member is movably mounted to the housing and is configured to roll within the housing and along a tissue surf ace of the subject, a connector for connecting the contact surf ace to the measuring device, and a position sensor for sensing movement of the moving member wherein the position sensor is configured to sense rolling motion of the moving member with respect to the housing,

the method comprising;

a) positioning the probe in contact with a segment of the subject, the segment being on a limb of the subject;

b) causing the measuring device to perform a sequence of impedance measurements;

c) moving the probe along the segment during the sequence of impedance measurements sothat the measuring device;

i) determines positional information along the segment using the position sensor; and

,

ii) determines impedance measurements along the segment; and

d) determining an impedance profile using the sequence of impedance values and the positional information, the impedance profile being indicative of a presence, absence, degree or location of oedema in the subject.

19. An apparatus for use in performing impedance measurements on a

subject, the apparatus comprising:

a) a probe including;

i) a housing configured to be held by an operator in use;

ii) a contact surface for contacting the subject, wherein the contact surface includes a moving member for moving relative to the subject, and wherein the moving member is movably mounted to the housing and is configured to roll within the housing and along a tissue surf ace of the subject;

iii) a connector for connecting the contact surface to a measuring device; and

,

iv) a positional sensor for sensing movement of the moving member, wherein the position sensor is configured to sense rolling motion of the moving member with respect to the housing,

b) a measuring device including a processing system for performing a sequence of impedance measurements as the probe is moved along a segment of the subject, so that the measuring device determines positional information along the segment using the position sensor, and determines impedance measurements along the segment and uses the impedance measurements and positional information to determine an impedance profile, the impedance profile representing variations in measured impedance along the segment.

20. The apparatus according to claim 19, wherein the housing is an elongate housing, the contact surf ace is provided at a first end of the housing and the connector is provided at a second opposing end of the housing.

21. The apparatus according to claim 19, wherein the housing is formed from an insulating material.

22. The apparatus according to claim 19, wherein the housing is formed from a poly(methyl) methacrylate tube.

23. The apparatus according to claim 19, wherein the contact surface has a convex shape.

24. The apparatus according to claim 19, wherein the moving member is a roller ball, and wherein the housing includes a shaped mounting for receiving the roller ball.

25. The apparatus according to claim 19, wherein the moving member is a cylindrical roller mounted on an axle.

26. The apparatus according to claim 19, wherein the probe includes a contact for electrically connecting the moving member to the connecter.

27. The apparatus according to claim 26, wherein the contact is a spring.

28. The apparatus according to claim 19, wherein the position sensor for sensing movement of the moving member includes at least one of:

a) an optical sensor; and

,

b) moving elements in contact with the moving member.

29. The apparatus according to claim 19, wherein the connector is for connecting to a lead of the measuring device.

30. A method of performing impedance measurements on a subject using an apparatus comprising:

a) a probe including;

i) a housing configured to be held by an operator in use;

ii) a contact surface for contacting the subject, wherein the contact surface includes a moving member for moving relative to the subject, and wherein the moving member is movably mounted to the housing and is configured to roll within the housing and along a tissue surf ace of the subject;

iii) a connector for connecting the contact surface to a measuring device; and

,

iv) a position sensor for sensing movement of the moving member, wherein the position sensor is configured to sense rolling motion of the moving member with respect to the housing,

b) a measuring device including a processing system, the method including;

i) positioning the probe in contact with a segment of the subject;

ii) causing a measuring device to perform a sequence of impedance measurements;

iii) moving the probe along the segment during the sequence of impedance measurements so that the measuring device determines impedance measurements along the segment and the position sensor senses motion of the moving member;

iv) determining positional information using the position sensor; and

v) using the impedance measurements and positional information to determine an impedance profile, the impedance profile representing variations in measured impedance along the segment.

31. A method according to claim 30, wherein the method includes, in the measuring device, displaying a representation of the impedance profile to thereby allow the impedance profile to be used in determining a presence, absence, degree or location of oedema in the subject.

32. A method according to claim 30, wherein the method includes, in the measuring device:

a) causing a sequence of first electrical signals to be applied to the subject via first electrodes provided on the subject; and

,

b) determining an indication of a sequence of second electrical signals measured via a second electrode positioned on the subject, and via the probe.

33. A method according to claim 32, wherein the method includes, in the measuring device, using an indication of the first and second signals to determine the impedance profile.

34. A method according to claim 32, wherein the method includes in the processing system:

a) causing a sequence of first signals to be applied to the subject via first electrodes provided on the subject;

b) determining an indication indicative of a sequence of second electrical signals measured via second electrodes provided on the subject; and

,

c) determining the sequence of impedance values using indications of the sequences of first and second signals.

35. A method according to claim 34, wherein one of the second electrodes is a probe, and wherein the method includes determining an indication of at least some of the second electrical signals as the probe is moved along the segment.

36. A method according to claim 30, wherein the method includes, in the processing system:

a) determining one or more impedance parameter values from measured impedance values; and

,

b) determining the impedance profile using the impedance parameter values.

37. A method according to claim 36, wherein the impedance parameter values include at least one of:

a) an impedance at infinite applied frequency (Ref;

));

b) an impedance at zero applied frequency (R0); and

,

c) an impedance at a characteristic frequency (Zc).

38. A method according to claim 37, wherein the method includes, in the processing system, determining the impedance parameter values at least in part using the equation:

39. A method according to claim 31, wherein the representation includes at least one of:

a) a baseline impedance profile for the segment;

b) a reference impedance profile derived from a normal population; and

,

c) an impedance profile for a contra-lateral segment.

40. A method according to claim 39, wherein the method includes, in the processing system:

a) determining one or more subject details; and

,

b) selecting a reference at least partially in accordance with the subject details.

41. A method according to claim 40, wherein the subject details include at least one of:

a) limb dominance;

b) ethnicity;

c) age;

d) sex;

e) weight; and

,

f) height.

42. An apparatus for use in diagnosing oedema in a body segment of a subject, the apparatus comprising:

a) a probe including;

i) a housing configured to be held by an operator in use;

ii) a contact surface for contacting the subject, wherein the contact surface includes a moving member for moving relative to the subject, and wherein the moving member is movably mounted to the housing and is configured to roll within the housing and along a tissue surf ace of the subject;

iii) a connector for connecting the contact surface to a measuring device; and

,

iv) a position sensor for sensing movement of the moving member, wherein the position sensor is configured to sense rolling motion of the moving member with respect to the housing,

b) a measuring device including a processing system for performing a sequence of impedance measurements as the probe is moved along a segment of the subject, so that the measuring device determines positional information along the segment using the position sensor, determines impedance measurements along the segment and uses the impedance measurements and positional information to determine an impedance profile, the impedance profile representing variations in measured impedance along the segment.

43. A method of diagnosing oedema in a body segment of a subject using apparatus comprising:

a) a probe including;

i) a housing configured to be held by an operator in use;

ii) a contact surface for contacting the subject, wherein the contact surface includes a moving member for moving relative to the subject, and wherein the moving member is movably mounted to the housing and is configured to roll within the housing and along a tissue surf ace of the subject;

iii) a connector for connecting the contact surface to a measuring device; and

,

iv) a position sensor for sensing movement of the moving member, wherein the position sensor is configured to sense rolling motion of the moving member with respect to the housing,

b) a measuring device including a processing system, the method including;

i) positioning the probe in contact with a segment of the subject;

ii) causing a measuring device to perform a sequence of impedance measurements;

iii) moving the probe along the segment during the sequence of impedance measurements so that the measuring device determines impedance measurements along the segment and the position sensor senses motion of the moving member

iv) determining positional information using the position sensor; and

v) using the impedance measurements and positional information to determine an impedance profile, the impedance profile being indicative of a presence, absence, degree or location of oedema in the subject.