Systems and methods for measuring oxygenation
First Claim
1. A method for optoacoustically determining oxygenation of a subject, the method comprising:
- emitting a first light having a first wavelength to tissue of the subject;
emitting a second light having a second wavelength to the tissue, the second wavelength being different from the first wavelength;
emitting a third light having a third wavelength to the tissue, the third wavelength being different from the first and second wavelengths;
detecting a first amplitude of acoustic pressure generated by the tissue in response to the first emitted light;
detecting a second amplitude of acoustic pressure generated by the tissue in response to the second emitted light;
detecting a third amplitude of acoustic pressure generated by the tissue in response to the third emitted light; and
determining oxygenation of the subject based on a first differential between the first and second amplitudes and a second differential between the first and third amplitudes.
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Accused Products
Abstract
Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.
69 Citations
30 Claims
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1. A method for optoacoustically determining oxygenation of a subject, the method comprising:
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emitting a first light having a first wavelength to tissue of the subject; emitting a second light having a second wavelength to the tissue, the second wavelength being different from the first wavelength; emitting a third light having a third wavelength to the tissue, the third wavelength being different from the first and second wavelengths; detecting a first amplitude of acoustic pressure generated by the tissue in response to the first emitted light; detecting a second amplitude of acoustic pressure generated by the tissue in response to the second emitted light; detecting a third amplitude of acoustic pressure generated by the tissue in response to the third emitted light; and determining oxygenation of the subject based on a first differential between the first and second amplitudes and a second differential between the first and third amplitudes. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A system for optoacoustically determining oxygenation of a subject, the system comprising:
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a light source configured to emit to tissue a first light having a first wavelength, a second light having a second wavelength different from the second wavelength, and a third light having a third wavelength different from the first and second wavelengths; an acoustic transducer configured to detect first, second, and third amplitudes of acoustic pressure generated by the tissue in response to the first, second and third emitted lights, respectively; and a processor configured to determine oxygenation of the subject based on a first differential between the first and second amplitudes and a second differential between the first and third amplitudes. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification