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Sensors for analyte detection and methods of manufacture thereof

  • US 10,314,527 B2
  • Filed: 08/02/2016
  • Issued: 06/11/2019
  • Est. Priority Date: 06/25/2010
  • Status: Active Grant
First Claim
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1. A sensor comprising:

  • a first tape;

    a second tape;

    the second tape being opposedly disposed on the first tape and in contact with the first tape; and

    one or multiple working electrodes, one or multiple reference electrodes and one or multiple counter electrode, each being disposed between the first tape and the second tape;

    where the working, reference and counter electrode are continuous along the length of the first tape and the second tape;

    the working, reference and counter electrodes not being in contact with one another;

    wherein a cross-sectional area of a first end of the sensor in a longitudinal direction that comprises a section of the working electrode, a section of the reference electrode and a section of the counter electrode is exposed to, contacts and detects analytes and a second end of the sensor in a longitudinal direction is not exposed to analytes;

    the working electrodes are etched to increase their surface area and catalytic nanoparticles are directly disposed and activated onto the etched surfaces to afford increase electro catalytic activity against H2O2 sensing;

    a thin film of permselective membrane is directly disposed onto said catalytic nanoparticles of the working electrodes to increase selectivity against H2O2 sensing, while retaining significant amount of the original nanoparticle sensitivity;

    a variety of analyte specific enzymes is directly disposed onto said permselective membrane to render the working, reference and counter electrodes operative to detect a variety of analytes via an electrochemical oxidation or reduction reaction; and

    wherein an old section of the sensor that contacts the analyte can be severed off to expose a new section of the sensor to detect the analyte.

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