Automated device for biologic drug distribution

• US 10,318,712 B2
• Filed: 03/22/2016
• Issued: 06/11/2019
• Est. Priority Date: 09/14/2011
• Status: Active Grant

• Current Assignee: Mirror Biologics, Inc.
• Original Assignee: Immunovative Therapies Ltd
• Inventors: Har-Noy, Michael
• Primary Examiner(s): Patel, Ramesh B
• Application Number:
  US15/077,493
• Publication Number:
  US 20160203295A1
• Time in Patent Office: 1,176 Days
• Field of Search: None
• CPC Class Codes: G05B 15/02 electric
• CPC Class Codes: G06Q 10/08 Logistics, e.g. warehousing, loading or distribution; Inventory or stock management
• CPC Class Codes: G06Q 50/22 Social work or social welfare, e.g. community support activities or counselling services
• CPC Class Codes: G07F 17/0092 for assembling and dispensing of pharmaceutical articles medical dispensers for private use, A61J7/00
• CPC Class Codes: G07F 9/105 Heating or cooling means, for temperature and humidity control, for the conditioning of articles and their storage dispensers for food articles requiring a processing by temperature treatment or conditioning before they are ready for dispensing G07F17/0064
• CPC Class Codes: G16H 10/40 for data related to laboratory analysis, e.g. patient specimen analysis
• CPC Class Codes: G16H 20/13 delivered from dispensers

Abstract

An apparatus stores and dispenses biologic drug compositions. The apparatus is an automated device that stores a biologic drug under the desired conditions. When authorized, the automated device processes the stored biologic drug by performing the desired processing steps to prepare the biologic drug for administration to a patient. The automated device includes a computing system to transmit patient information to a remote location and receive authorization from a remote location.

Claims

1. An automated device comprising:

a storage chamber in a cooling unit for storing one or more doses of a biologic drug;

a processing compartment within the automated device comprising one or more chambers for processing the one or more doses of the biologic drug, wherein the processing compartment comprises apparatus and materials in the one or more chambers for formulation of the biologic drug prior to administration to a patient and wherein the one or more chambers comprises a mixing chamber for mixing the biologic drug with activating agents;

a system for receiving authorization to move the one or more doses of the biologic drug from the storage chamber to the one or more chambers of the processing compartment; and

a dispensing chamber for receiving the biologic drug from the processing compartment after formulation.

2. The device of claim 1 wherein the cooling unit comprises a freezer for maintaining the biologic drug.

3. The device of claim 2 wherein the freezer maintains the biologic drug at about −

70°

C.

4. The device of claim 1 wherein the biologic drug comprises T-cells and the activating agents comprise agents that cross-link the CD3 and CD28 cell surface proteins of the T-cells.