Platforms for mitral valve replacement

• US 10,321,988 B2
• Filed: 12/20/2012
• Issued: 06/18/2019
• Est. Priority Date: 12/21/2011
• Status: Active Grant

• Current Assignee: Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Original Assignee: Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Inventors: Gorman, III, Joseph H., Gorman, Robert C., Gillespie, Matthew J.
• Primary Examiner(s): Templeton, Christopher L
• Application Number:
  US14/366,943
• Publication Number:
  US 20140358222A1
• Time in Patent Office: 2,371 Days
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00606 Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/2445 Annuloplasty rings in direct contact with the valve annulus
• CPC Class Codes: A61F 2210/009 magnetic
• CPC Class Codes: A61F 2220/0025 Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
• CPC Class Codes: A61F 2230/0095 Saddle-shaped
• CPC Class Codes: A61F 2250/006 modular

Abstract

A mitral valve prosthesis is percutaneously and/or transapically deployed in at least two stages. In a first stage, a mitral annular ring platform adapted for percutaneous delivery is delivered to and anchored in the mitral valve annulus. In the second stage, a valved-stent mitral valve prosthetic device adapted for percutaneously delivery is delivered to the mitral valve annulus for mounting in the mitral annular ring platform. This approach provides a consistent platform for accepting valved-stent mitral valve prosthetic devices from different vendors to be used.

Claims

1. A mitral valve prosthesis comprising:

a mitral annular ring platform device adapted for percutaneous and/or transapical delivery to and anchoring in a mitral valve annulus of a subject, the mitral annular ring platform device comprising

left and right discs configured to straddle the subject'"'"'s atrial septum when said platform is deployed to the subject'"'"'s heart,

a bridge region that extends from an outermost circumferential rim of the left disc and that is interposed between the left disc and a mitral annular ring-shaped or oval-shaped platform portion, the mitral annular ring-shaped or oval-shaped platform portion extending from a side of the bridge region opposite the left disc and being adapted to lie across the subject'"'"'s mitral valve annulus, wherein the mitral annular ring platform device is configured for delivery and

implantation from a compressed state by deployment from a catheter; and

a valved-stent mitral valve prosthetic device adapted to be percutaneously and/or transapically delivered to the mitral valve annulus for mounting in said mitral annular ring-shaped or oval-shaped platform.