Fluidic optical cartridge
First Claim
1. An apparatus configured to engage with a host structure, the apparatus comprising:
- a base plate;
a fluidic structure that includes;
a channel having a cross-section dimension through which objects can travel along respective paths during operation of the apparatus, the channel having at least one transparent wall;
a first end portion affixed to the base plate, and comprising an inlet coupled to a first end of the channel, wherein the inlet is configured to engage a pipettor tip;
a second end portion coupled to a second end of the channel, the second end of the channel positioned opposite the first end of the channel, the second end portion having a cross-section dimension larger than the cross-section dimension of the channel; and
a flange coupled to the second end portion and configured to reversibly engage with the host structure;
at least one optical component affixed to the base plate and disposed in a fixed spatial relationship with the fluidic structure, and disposed in a path of measurement light, the measurement light passing from the optical component into the fluidic structure through the transparent wall to the objects traveling through the channel, output light emanating from the objects traveling in the channel in response to the measurement light and passing out of the fluidic structure through the transparent wall; and
at least one optical filter assembly positioned directly in contact with the at least one transparent wall.
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Accused Products
Abstract
Embodiments are directed to an apparatus that includes a fluidic structure and optical components. The fluidic structure includes a transparent channel through which objects in an analyte fluid can travel along respective paths during operation of the apparatus. The optical components are configured to provide measurement light to the objects traveling through the transparent channel. The fluidic structure is configured to reversibly engage with a host structure. The host structure includes a source of the measurement light and electronics to receive and process output light emanating from the objects traveling in the channel. The fluidic structure makes an air-tight seal when engaged with the host structure.
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Citations
17 Claims
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1. An apparatus configured to engage with a host structure, the apparatus comprising:
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a base plate; a fluidic structure that includes; a channel having a cross-section dimension through which objects can travel along respective paths during operation of the apparatus, the channel having at least one transparent wall; a first end portion affixed to the base plate, and comprising an inlet coupled to a first end of the channel, wherein the inlet is configured to engage a pipettor tip; a second end portion coupled to a second end of the channel, the second end of the channel positioned opposite the first end of the channel, the second end portion having a cross-section dimension larger than the cross-section dimension of the channel; and a flange coupled to the second end portion and configured to reversibly engage with the host structure; at least one optical component affixed to the base plate and disposed in a fixed spatial relationship with the fluidic structure, and disposed in a path of measurement light, the measurement light passing from the optical component into the fluidic structure through the transparent wall to the objects traveling through the channel, output light emanating from the objects traveling in the channel in response to the measurement light and passing out of the fluidic structure through the transparent wall; and at least one optical filter assembly positioned directly in contact with the at least one transparent wall. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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Specification