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Chromatographic system temperature control system

  • US 10,324,069 B2
  • Filed: 02/24/2017
  • Issued: 06/18/2019
  • Est. Priority Date: 02/24/2017
  • Status: Active Grant
First Claim
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1. A chromatographic system, comprising:

  • a first chromatographic component selected from the group consisting of a transport line, a valve, a sample loop, a column, and a detector;

    a second chromatographic component selected from the group comprising a transport line, a valve, a sample loop, a column, and a detector;

    a first electrically-controlled heating element associated with the first chromatographic component;

    a second electrically-controlled heating element associated with the second chromatographic component;

    a first temperature sensor associated with the first chromatographic component, the first temperature sensor generating a first temperature sensor signal;

    a second temperature sensor associated with the second chromatographic component, the second temperature sensor generating a second temperature sensor signal;

    a power supply;

    a temperature controller, the temperature controller having a processor, a first electrically-controlled heating element output, a second electrically-controlled heating element output, a first temperature sensor input, and a second temperature sensor input;

    the processor adapted to receive the first temperature sensor signal at the first temperature sensor input and to construct a first actual time-temperature profile;

    the processor adapted to receive the second temperature sensor signal at the second temperature sensor input and to construct a second actual time-temperature profile;

    the processor adapted to receive a first time-temperature profile for the first chromatographic component;

    the processor adapted to receive a second time-temperature profile for the second chromatographic component selected from the group of the first time-temperature profile and the first actual time-temperature profile of the first chromatographic component;

    the processor having a first power supply control for controlling a first output from the power supply to the first electrically-controlled heating element output;

    the processor having a second power supply control for controlling a second output from the power supply to the first electrically-controlled heating element output;

    the processor adapted to alter the first output from the power supply so the first actual time-temperature profile approaches the first time-temperature profile;

    the processor adapted to alter the second output from the power supply so the second actual time-temperature profile approaches the second time-temperature profile.

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