Monitoring system

• US 10,327,665 B2
• Filed: 08/18/2016
• Issued: 06/25/2019
• Est. Priority Date: 07/01/2005
• Status: Active Grant

• Current Assignee: ImpediMed Limited
• Original Assignee: ImpediMed Limited
• Inventors: Chetham, Scott, Ward, Andrew William, Kennedy, James McFarlane
• Primary Examiner(s): Eiseman, Adam J
• Application Number:
  US15/240,555
• Publication Number:
  US 20160354008A1
• Time in Patent Office: 1,041 Days
• CPC Class Codes: A61B 2562/08 Sensors provided with means for identification, e.g. barcodes or memory chips
• CPC Class Codes: A61B 2562/166 the sensor is mounted on a specially adapted printed circuit board
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/0535 Impedance plethysmography for measuring blood flow A61B5/0295
• CPC Class Codes: A61B 5/0537 Measuring body composition by impedance, e.g. tissue hydration or fat content
• CPC Class Codes: A61B 5/6801 specially adapted to be attached to or worn on the body surface
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F
• CPC Class Codes: A61B 5/7257 using Fourier transforms
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: A61B 5/7495 using a reader or scanner device, e.g. barcode scanner

Abstract

Apparatus for performing impedance measurements on a subject. The apparatus includes a first processing system for determining an impedance measurement procedure and determining instructions corresponding to the measurement procedure. A second processing system is provided for receiving the instructions, using the instructions to generate control signals, with the control signals being used to apply one or more signals to the subject. The second processing system then receives first data indicative of the one or more signals applied to the subject, second data indicative of one or more signals measured across the subject and performs at least preliminary processing of the first and second data to thereby allow impedance values to be determined.

Claims

1. A system for performing impedance measurements on a subject, the system comprising:

a plurality of electrodes configured to be placed in contact with the skin of the subject;

a signal generator coupled to at least a first subset of the plurality of electrodes;

a sensor coupled to at least a second subset of the plurality of electrodes; and

a first processing system configured to;

receive configuration data from an external system, the configuration data being indicative of at least one feature, the configuration data comprising instructions representing applications software or firmware;

generate control signals to cause the signal generator to generate one or more alternating signals which are applied to the subject via the first subset of the plurality of electrodes;

receive an indication of sensed signals through the subject from the sensor; and

wirelessly communicate information relating to the indication of sensed signals to a second processing system after receiving the indication of sensed signals; and

,

a housing, the housing comprising at least the signal generator, the sensor, and the first processing system, and wherein the system is configured to measure and record at least one of;

changes in fluid levels, body composition and diagnosis of the presence, absence or degree of at least one of oedema, pulmonary oedema, lymphodema, and cardiac function.

2. The system of claim 1, wherein the second processing system comprises a smart phone.

3. The system of claim 1, wherein the first processing system is configured to perform at least preliminary processing of the indication of sensed signals, and wherein the second processing system is configured to communicate information regarding the processing of the indication of sensed signals to the first processing system.

4. The system of claim 1, wherein the first processing system comprises:

a processor;

a memory; and

an input/output device.

5. The system of claim 1, wherein the first processing system includes programmable hardware, the operation of which is controlled using instructions, and wherein the instructions are stored within inbuilt memory on the first processing system or downloaded from the second processing system.

6. The system of claim 1, wherein the first processing system comprises a Field Programmable Gate Array (FPGA).

7. The system of claim 1, wherein the signal generator includes a current circuit and the sensor includes a voltage circuit, and wherein the system further comprises:

a current ADC configured to;

receive signals from the current circuit; and

,

provide the indication of the one or more signals applied to the subject to the first processing system;

a voltage ADC configured to;

receive signals from a voltage circuit; and

,

provide the indication of the one or more signals measured from the subject to the first processing system; and

a control signal DAC configured to;

receive the control signals from the first processing system; and

,

provide analogue control signals to a current circuit to thereby cause one or more current signals to be applied to the subject in accordance with the control signals.

8. The system of claim 7, further comprising:

at least one buffer circuit configured to;

receive voltage signals from a voltage electrode;

filter and amplify the voltage signals; and

,

transfer the filtered and amplified voltage signals to the voltage ADC via a differential amplifier;

at least one current source circuit configured to;

receive one or more control signals;

filter and amplify the control signals to thereby generate one or more current signals;

apply the current signals to a current electrode; and

transfer an indication of the applied signals to the current ADC.

9. The system of claim 8, wherein the first processing system is configured to:

receive signals from the current and voltage ADCs; and

perform preliminary processing of the signals.

10. The system of claim 9, wherein the preliminary processing includes at least one of:

extracting ECG signals; and

filtering the signals.

11. The system of claim 1, wherein the configuration data is indicative of at least one feature and wherein the system is configured to:

determine, using the configuration data, instructions representing the at least one feature; and

,

cause, using the instructions, at least one of;

at least one impedance measurement to be performed; and

,

at least one impedance measurement to be analysed.

12. The system of claim 11, wherein the second processing system receives configuration data and uses the configuration data to update instructions used by the first processing system.

13. The system of claim 1, wherein the second processing system:

analyses impedance values determined by the first processing system; and

determines one or more biological parameters using the analysis.

14. The system of claim 1, wherein the second processing system:

determines an impedance measurement procedure; and

,

at least one of;

analyses impedance measurements in accordance with the impedance measurement procedure; and

,

causes the first processing system to perform impedance measurements in accordance with the impedance measurement procedure.

15. The system of claim 14, wherein the second processing system includes a store for storing profiles representing predetermined impedance measurement procedures, the second processing system being coupled to an input device to thereby determine one of the impedance measurement procedures in accordance with input commands from an operator.

16. The system of claim 1, wherein the first processing system:

receives an indication of the one or more signals applied to the subject from the signal generator;

receives an indication of one or more signals measured across the subject from the sensor; and

,

performs at least preliminary processing of the indications to thereby allow impedance values to be determined.

17. An apparatus for performing impedance measurements on a subject, the apparatus including:

a signal generator coupled to electrodes configured to be placed on a subject;

a sensor coupled to electrodes configured to be placed on a subject;

a processing system configured to;

perform configuration by;

receiving configuration data from an external system, the configuration data being indicative of at least one feature, the configuration data comprising instructions representing applications software or firmware;

determining, using the configuration data, instructions representing the at least one feature; and

,

causing, using the instructions, at least one of;

at least one impedance measurement to be performed; and

,

at least one impedance measurement to be analysed; and

perform impedance measurements by;

generating control signals to thereby cause the signal generator to generate one or more alternating signals which are applied to the subject via the drive electrodes;

receiving an indication of sensed signals through the subject from the sensor; and

,

determining impedance values at least in part using the indication of the sensed signals.

18. The apparatus of claim 17, wherein the processing system is configured to:

determine an indication of the at least one feature using the configuration data; and

,

determine the instructions using the indication of the at least one feature.

19. The apparatus of claim 17, wherein the processing system is configured to decrypt received configuration data.

20. The apparatus of claim 17, wherein the processing system is configured to:

determine a device identifier associated with the measuring device;

determine, using the device identifier, a key; and

,

decrypt the received configuration data using the key.

21. The apparatus of claim 17, wherein the processing system is configured to:

receive instructions from a second processing system, the instructions selected using the configuration data; and

generate the control signals using selected instructions.

22. The apparatus of claim 17, wherein the processing system is configured to:

receive instructions from a second processing system;

or

access the instructions from a store in response to a communication from a second processing system.

23. The apparatus of claim 17, wherein the processing system receives the configuration data from at least one of a computer system and a communications network.

24. The method of claim 17, wherein receiving configuration data from an external system comprises receiving the configuration data via a wireless connection with an external system.

25. The method of claim 17, wherein receiving configuration data from an external system comprises receiving the configuration data via a wired connection with an external system.

26. A system for performing impedance measurements on a subject, the system including:

a first processing system coupled to a signal generator and a sensor, the signal generator and the sensor being coupled to respective electrodes provided in contact with the subject in use, the first processing system configured to;

receive configuration data from an external system, the configuration data being indicative of at least one feature;

determine, using the configuration data, instructions representing the at least one feature; and

generates control signals which causes the signal generator to generate one or more alternating signals which are applied to the subject via the electrodes, and the sensor configured to determine voltage across or current through the subject, using the electrodes, and transfer appropriate signals to the first processing system; and

a second processing system in wireless communication with the first processing system, the second processing system configured to analyze the impedance values based on an indication of the signals which are applied to the subject and the voltage across or current through the subject, and wherein the system is configured to measure and record at least one of;

changes in fluid levels, body composition and diagnosis of the presence, absence or degree of at least one of oedema, pulmonary oedema, lymphodema, and cardiac function.

27. The system of claim 26, wherein the second processing system comprises a smart phone.

28. The system of claim 26, wherein the apparatus is configured to

cause, using the instructions, at least one of:

at least one impedance measurement to be performed; and

,

at least one impedance measurement to be analyzed.

29. A system for performing impedance measurements on a subject, the system comprising:

a plurality of electrodes configured to be placed in contact with skin of the subject;

a signal generator coupled to at least a first subset of the plurality of electrodes;

a sensor coupled to at least a second subset of the plurality of electrodes; and

a first processing system configured to;

receive configuration data from an external system, the configuration data being indicative of at least one feature, the configuration data comprising instructions representing applications software or firmware;

generate control signals to cause the signal generator to generate one or more alternating signals which are applied to the subject via the first subset of the plurality of electrodes;

receive an indication of sensed signals through the subject from the sensor; and

communicate information relating to the indication of sensed signals to a second processing system after receiving the indication of sensed signals, the second processing system comprising a smart phone, and wherein the system is configured to measure and record at least one of;

changes in fluid levels, body composition and diagnosis of the presence, absence or degree of at least one of oedema, pulmonary oedema, lymphodema, and cardiac function.

30. A system for performing impedance measurements on a subject, the system comprising:

a plurality of electrodes configured to be placed in contact with the skin of the subject;

a signal generator coupled to at least a first subset of the plurality of electrodes;

a sensor coupled to at least a second subset of the plurality of electrodes; and

a first processing system configured to;

receive configuration data from an external system, the configuration data being indicative of at least one feature, the configuration data comprising instructions representing applications software or firmware;

generate control signals to cause the signal generator to generate one or more alternating signals which are applied to the subject via the first subset of the plurality of electrodes;

receive an indication of sensed signals through the subject from the sensor; and

wirelessly communicate information relating to the indication of sensed signals to an external processing system after receiving the indication of sensed signals, wherein the system is configured to measure and record changes in fluid levels.

31. A system for performing impedance measurements on a subject, the system comprising:

a plurality of electrodes configured to be placed in contact with the skin of the subject;

a signal generator coupled to at least a first subset of the plurality of electrodes;

a sensor coupled to at least a second subset of the plurality of electrodes; and

a first processing system configured to;

receive configuration data from an external system, the configuration data being indicative of at least one feature, the configuration data comprising instructions representing applications software or firmware;

generate control signals to cause the signal generator to generate one or more alternating signals which are applied to the subject via the first subset of the plurality of electrodes;

receive an indication of sensed signals through the subject from the sensor; and

wirelessly communicate information relating to the indication of sensed signals to an external processing system after receiving the indication of sensed signals, wherein the system is configured to record diagnoses of the presence, absence or degree of at least one of oedema, pulmonary oedema, lymphodema, and cardiac function.

32. A system for performing impedance measurements on a subject, the system comprising:

a plurality of electrodes configured to be placed in contact with the skin of the subject;

a signal generator coupled to at least a first subset of the plurality of electrodes;

a sensor coupled to at least a second subset of the plurality of electrodes; and

a first processing system configured to;

receive configuration data from an external system, the configuration data being indicative of at least one feature, the configuration data comprising instructions representing applications software or firmware;

generate control signals to cause the signal generator to generate one or more alternating signals which are applied to the subject via the first subset of the plurality of electrodes;

receive an indication of sensed signals through the subject from the sensor; and

wirelessly communicate information relating to the indication of sensed signals to an external processing system after receiving the indication of sensed signals, wherein the system is configured to measure and record changes in body composition.