×

Analyte sensor apparatuses comprising multiple implantable sensor elements and methods for making and using them

  • US 10,327,678 B2
  • Filed: 04/08/2014
  • Issued: 06/25/2019
  • Est. Priority Date: 07/31/2008
  • Status: Active Grant
First Claim
Patent Images

1. An apparatus for monitoring an analyte in a patient, the apparatus comprising:

  • a base adapted to secure the apparatus to the patient;

    a first piercing member coupled to and extending from the base;

    a first electrochemical sensor operatively coupled to the first piercing member, wherein the first electrochemical sensor comprises a plurality of working, counter and reference electrodes that are grouped together as a unit and positionally distributed in a repeating pattern of units;

    a second piercing member coupled to and extending from the base;

    a second electrochemical sensor operatively coupled to the second piercing member, wherein the second electrochemical sensor comprises a plurality of working, counter and reference electrodes that are grouped together as a unit and positionally distributed in a repeating pattern of units; and

    wherein;

    the plurality of working electrodes, the plurality of counter electrodes and the plurality of references electrodes in the first electrochemical sensor and the second electrochemical sensor are clustered together in repeating units consisting essentially of one working electrode, one counter electrode and one reference electrode;

    at least one physiological characteristic monitored by the first or the second electrochemical sensor comprises a concentration of a naturally occurring analyte in the patient;

    the first and second piercing members are disposed on the base in a configuration selected so that the first piercing member disposes the first electrochemical sensor in a first tissue compartment of the patient and the second piercing member disposes the second electrochemical sensor in a second tissue compartment of the patient; and

    the first and second piercing members are disposed on the base in a configuration selected to avoid a physiological response that can result from implantation of the first electrochemical sensor from altering a sensor signal generated by the second electrochemical sensor.

View all claims
  • 0 Assignments
Timeline View
Assignment View
    ×
    ×